The necessity of integrated navigation complexes (INC) construction is substantiated. It is proposed to include in the complex the following inertial systems: inertial, satellite and visual. It helps to increase the accuracy of determining the coordinates of unmanned aerial vehicles. It is shown that in unfavorable cases, namely the suppression of external noise of the satellite navigation system, an increase in the errors of the inertial navigation system (INS), including through the use of accelerometers and gyroscopes manufactured using MEMS technology, the presence of bad weather conditions, which complicates the work of the visual navigation system. In order to ensure the operation of the navigation complex, it is necessary to ensure the suppression of interference (noise). To improve the accuracy of the INS, which is part of the INC, it is proposed to use the procedure for extracting noise from the raw signal of the INS, its prediction using neural networks and its suppression. To solve this problem, two approaches are proposed, the first of which is based on the use of a multi-row GMDH algorithm and single-layer networks with sigm_piecewise neurons, and the second is on the use of hybrid recurrent neural networks, when neural networks were used, which included long-term and short-term memory (LSTM) and Gated Recurrent Units (GRU). Various types of noise, that are inherent in video images in visual navigation systems are considered: Gaussian noise, salt and pepper noise, Poisson noise, fractional noise, blind noise. Particular attention is paid to blind noise. To improve the accuracy of the visual navigation system, it is proposed to use hybrid convolutional neural networks.