The review covers urgent domestic and foreign researches of psychogenetic factors of aggressive behavior. The authors consider cytogenetic mechanisms providing mental activity and behavioural activity of the person, offer the concept of the control system of information coding, and specify features of a genotype-environmental interaction in forming aggressive behavior. Classification of forms of aggression is given. Approaches to interpretation of this concept are considered. The theories explaining the nature of aggression (J. Dollard and L. Berkowitz’s frustration theory, A. Bandura’s theory of social learning, K. Lorentz and S. Freud’s theory of instinctual drives, biological theory) are analyzed.The brain mechanisms underlying different forms of aggressive behavior are described.A large number of domestic and foreign studies devoted to the problem of genetic determination of mental processes and behavior is analyzed. The authors bring forward the review of researches of genetic foundations of aggressive behavior. They describe approaches recognized insolvent today (the extra Y-chromosome theory, the “genesign” system, the “generalist genes” concept) and offer conceptions confirmed today: the role of monoamine neuromodulators (the interrelation between various forms of aggressive behavior and neurotransmitter systems of the brain), testosterone is described; the influence of the social-economic status and the environmental factors is considered. The available psychogenetic data is described from the point of view of the additive model of development. On the whole, they note a polygenic nature of the inheritance of aggression (the genes coding information of the olfactory, hormonal, mediator systems are biological factors of aggression).Perspectives of the development of this research area are outlined: the bioinformation analysis of molecular mechanisms of activity of the central nervous system by means of studying the expression of genes in brain cells; the review of the first results obtained by means of this method is offered.
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