The study is based on the realities of the state and prospects for the development of the national higher education system during the period of active integration processes into the European Higher Education Space and the European Research Space. The analysis of the following aspects is carried out: the current state of the Ukrainian education system, the actions of the Ministry of Education and Science of Ukraine to develop cooperation with international organizations in various areas, in particular, to promote innovation and entrepreneurship in Ukraine, which is especially relevant for the industrial region - Zaporizhzhia region, which concentrates such strategic sectors of the Ukrainian economy as metallurgy, mechanical engineering, electricity. It is emphasized that the legislation of Ukraine on education sets such a goal - development, effective functioning of the education quality assurance system in Ukraine, implementation of a constant and consistent process of improving the quality of education and it is noted that the development strategy of Zaporizhzhia National University (hereinafter ZNU) is to develop and consolidate leading positions aimed at training highly qualified specialists, development of scientific research, increasing the role of the innovative component in the activities of ZNU and its integration into the European and world educational space. It is proved that the restructuring of higher education institutions in Ukraine helps to increase the efficiency of their operation. The changes that took place in the process of joining the Zaporizhzhia State Academy of Engineering (hereinafter ZSIA) to ZNU and as a result of the creation of a structural unit - Engineering Educational and Scientific Institute (hereinafter EESI), which has a non-faculty structure and consists of fifteen departments of different areas of training, are analyzed. The article substantiates the strategic advantages of the project of joining ZSIA to ZNU, which made it possible to diversify the educational programs of Bachelors and Masters educational levels in economics and management with the aim of curricula modern updating and further training of highly qualified specialists for industrial regions, in particular for industrial enterprises, in the fields of mechanical engineering, electric power and small and medium-sized businesses serving "large" industrial enterprises in the region. The results of work on improving the quality of higher education in EESI ZNU in the areas of non-formal and informal education, academic mobility, dual education, creating unique learning conditions for privileged categories of students and students with special needs, further integration of economic and managerial education in engineering education are analyzed.