The transformation of scientific and technological achievements of universities is of great importance for regional economic development and the development of scientific and technological innovation. Based on three aspects — the input of innovative resources, the output of scientific and technological achievements and the transformation of scientific and technological achievements — this study selected 13 indicators, such as scientific and technical expenditures, the number of scientific and technical personnel, the results of publication activities, intellectual activity, patents, contracts and income from the transformation of scientific and technological achievements, to build an indicator system for the transformation of scientific and technological achievements of colleges and universities; at the same time 7 indicators were selected, such as the number of scientific and technological personnel, funding, the number of patents and scientific and technological business-incubators, to build a regional system for assessing scientific and technical potential, a system for assessing regional scientific and technical innovation potential. Based on the factor analysis method, the transformation scores of scientific and technological achievements of universities and regional scientific and technological innovations in each region of China in 2019–2021 were calculated; secondly, using the Coupling coordination degree model, the degree of relationship and coordination between the university system of transformation of scientific and technological achievements and the regional scientific and technological innovation system in different regions of China was calculated. The study showed that the level of scientific and technological achievements is uneven and not high; points of innovative development of Chinese regions have been identified. Thus, the transformation of scientific and technological achievements of universities is a necessary path for the scientific, technological and economic development of regions, when it is necessary to combine the needs of regional development, take measures to strengthen support for scientific and technological personnel, create platforms for sharing resources, and improve policies in the field of intellectual property in order to promote the industrialization of scientific and technological achievements, promote regional scientific and technological innovations and develop regional industry.
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