DC breakers and their associated control are seen as important lever for the DC grid expansion. In complement to dynamic studies, as intermediate step towards on-site implementation, factory tests using real control and protection hardware enable to fine tune control sequences, to check the software implementation and then test the coordination and interaction between different devices connected to the same grid.This article presents a hardware-in-the-loop setup for testing industrial DCCB controllers and their interoperability with converter controllers. A hybrid DCCB model suitable for real-time simulation has been developed and then validated against offline model. Industrial DCCB controller functions are described. A set-up of three-terminal DC grid with physical controllers for one MMC converter station and 12 DCCBs is described. The results of two application cases including cable energization and fault clearance are presented and discussed.