The article presents the data of an empirical study of the features of the adaptation resources of the population living under the conditions of the armed conflict. The study involved 723 people of both genders living in the immediate area of the armed conflict, their age ranging from 17 to 75 years old. It is empirically shown that the respondents of the first group (areas of low-intensity shelling) are generally characterized by high activity, cheerfulness, calmness, healthy optimism, they are active and satisfied with life; these indicators are more pronounced in women aged 19-35 years. It is established that in the first group almost half of the respondents show a high level of neuropsychic resistance; a higher level of it being observed in men. It has been determined that the respondents of the second group (areas of intensive shelling) are characterized by displays of irritability, anxiety, and also depression, despair. They are characterized by fast fatigue, low working capacity, lethargy, reduced energy potential and emotional stability, moral normalization. This group of people shows an average neuropsychic resistance, there are signs of stress and mental disadaptation (mainly in women aged 35-60 and older), they are less satisfied with life on the whole than the respondents of the first group, and they also give a lower estimate of their personal success. Most pronounced these indicators were in women 19-35 years old and in men 35-60 years old. It is also established that the subjects of both groups reveal a high level of personal adaptation potential, as evidenced by their rapid adaptation to the new reality conditions. The most adaptive in the first and second groups are young people aged 17-19, and also women aged 19-35. The main conclusions of this study are as follows: long-term residence in the area of the armed conflict, especially in the areas of intense shelling, significantly affects the adaptation capacity of a person, activates his life resources, on the one hand, and, on the other hand, it may have negative consequences for the mental health and lead to disadaptation, and a decrease in the adaptation potential.