Mint Extract Research Articles

Antifungal activity of cinnamon and mint extracts against white and basal rot of garlic

Antifungal activity of cinnamon and mint extracts against white and basal rot of garlic

Antioxidant and Elastase, Tyrosinase, α-Glucosidase Inhibitory Effects of Five Types of Mint Extracts

Purpose: This study evaluated the biological activity of five types of mints (Peppermint, Spearmint, Chocomint, Applemint, Pineapplemint).Methods: Five types of mints were extracted with an ethanol solvent to compare the total polyphenol and total flavonoid content, scavenging activities of DPPH and ABTS radical, SOD-like activity, and inhibitory effects of elastase, tyrosinase, and α-glucosidase.Results: All five types of mint extracts were confirmed to be effective significantly in concentration. The total polyphenol content was found to be effective in the order of peppermint>spearmint>chocomint>pineapplemint>applemint, and the total flavonoid content was found to be effective in the order of peppermint> chocomint>spearmint>pineapplemint>applemint. The DPPH radical scavenging activity was found to be in the order of peppermint>spearmint>chocomint> pineapplemint>applemint, and the ABTS radical scavenging activity was found to be in the order of peppermint>chocomint>spearmint>pineapplemint>applemi nt. The SOD-like activity was found to be in the order of peppermint>chocomint> spearmint> pineapplemint>applemint. The inhibitory effects of elastase, tyrosinase, α-glucosidase were found to be in the order of peppermint>spearmint>chocomint> pineapplemint>applemint.Conclusion: As above results, all five types of mint extracts were verified to be effective significantly in concentration. In particular, peppermint indicated the highest total polyphenol, total flavonoid, DDPH and ABTS radical scavenging activity, and SOD-like activity, while chocomint displayed the highest tyrosine, elastase, and α-glucosidase inhibitory effects.

Physical Quality Evaluation of Toothpaste Preparation with a Combination of Siwak Wood (Salvadora persica) and Mint Leaf (Coleus amboinicus L.) Extracts

Oral health, which includes dental health, is a condition in which the oral cavity, teeth and other supporting tissue structures are free from bacteria and pain so that they can function optimally. Oral health can be maintained by regularly brushing your teeth using a toothpaste that has an antibacterial effect. Natural ingredients that have an antibacterial effect are siwak wood and mint leaves. Siwak wood contains salvadorine, which has shown to have an antibacterial effect on cariogenic bacteria such as Streptococcus mutans. Mint leaves can be used as an antibacterial and can provide a fresh taste in the mouth. This study aims to determine the results of the evaluation of the physical quality of toothpaste with a combination of siwak wood (Salvadora persica) and mint (Coleus amboinicus L.) extracts. It is included as observational research. The physical quality evaluation results are it is a light brown toothpaste, has a mint aroma, has a slightly spicy sweet taste with a semi-solid dosage form, it is homogeneous with pH 6, and spreadability of 4.28 cm.

Active edible coating based on guar gum with mint extract and antibrowning agents for ber (Ziziphus mauritiana) fruits preservation

Active edible coating based on guar gum with mint extract and antibrowning agents for ber (Ziziphus mauritiana) fruits preservation

Antimicrobial activity of the mint extract against campylobacter jejueni isolated from chicken sample

Foodborne infectious diseases are seen around the world. One of the most common contaminants found in chicken meat products is Campylobacter jejuni. This study tries to: To assess the utilization of Mint extract in various concentrations as natural antimicrobial against C. jejueni, 100 chicken samples were collected From the city center of AL- Diwaniyah, 50 samples of fresh poultry meat and 50 samples of frozen poultry meat, and the evaluation was done on them after preparation.The antimicrobial activity of methanolic, ethanolic, and aqueous extracts of mint was evaluated in multi-well micro-titer plates using the well diffusion method. Mint extract was evaluated for antimicrobial property against C. jejuni at different concentrations (80%, 40%, and 20%), and the highest inhibitory effect was observed in the ethanolic extract of mint, followed by the methanolic extract, while the aqueous extract was active only at a high concentration of 80% using the well diffusion method. Due to the biologically active properties of the compounds in mint, which are antimicrobial, antibacterial, anti-inflammatory, anticancer, antioxidant, and antifungal, mint extracts exhibit biological activity against C. jejueni.

Comparative Study and Analysis of Structural and Optical Properties of Zinc Oxide Nanoparticles using Neem and Mint Extract prepared by Green synthesis method

This work reports the comparative analysis and study of synthesis of Zinc oxide (ZnO) Nanoparticles by using Neem and Mint leaves’ extract by green synthesis method. Green synthesis is a non-toxic, eco-friendly, and low-cost approach to synthesize Nanoparticles. Leaves of Neem and Mint are used for synthesis of ZnO Nanoparticles by boiling at temperature 60°C. The synthesized ZnO NPs (of both extracts) are then characterized separately by using XRD (X-Ray diffraction) confirms the hexagonal (wurtzite) structure of the ZnO nanoparticles with crystalline size 25.51 nanometer and 26.29 nanometer for Neem and Mint respectively, FTIR (Fourier transform infrared spectroscopy) shows the highest peak at 1047cm-1 and 3295cm-1 for Mint and Neem respectively. UV spectroscopy shows the absorption peak for ZnO nanoparticles at 366 nm and 356 nm for Mint and Neem respectively.

Green synthesis and characterization of copper nanoparticles for investigating their effect on germination and growth of wheat.

Today, different types of nanoparticles (NPs) are being synthesized and used for medical and agricultural applications. In this study, copper nanoparticles (CuNPs) were synthesized using the aqueous extract of mint (Mentha longifolia L.). For the characterization of CuNPs, UV-visible spectroscopy, scanning electron microscopy, X-ray diffraction, and Fourier transform infrared spectrometry were used. The UV-Visible absorption peak at 558 nm confirmed the formation of CuNPs. The XRD pattern confirmed the phase-centered crystalline nature of CuNPs. FTIR analysis showed the O-H, Cu-H and C-C bonds, indicating the active role of these functional groups as reducing agents of Cu ions to CuNPS. The synthesized NPs were found to have an almost spherical shape with an average size of 23 nm. When applied to wheat, a condition dependent effect of CuNPs was found. Variety 18-Elite Line 1, Elite Line 3, and 18-Elite Line 6 showed maximum germination and growth rate at 50 mg CuNPs/L, while variety 18-Elite Line 5 showed that increase at 25 mg CuNPs/L. Beyond these concentrations, the seed germination and growth of wheat declined. In conclusion, the application of CuNPs showed a beneficial effect in improving the growth of wheat at a certain concentration.

Does Mint have Antifungal and Antibacterial effect

Introduction: Patients undergoing fixed appliance treatment have many attachments on their teeth that act as an active site as plague retention sites for the attachment of food particles and subsequently microorganisms which later cause caries and periodontal diseases Orthodontic patients have an increase in the microorganisms because of the active sites for the plaque accumulation. Almost all conventional mouth freshners contain alcohol and fluoride, which are toxic (even lethal) if used in large amounts. This is often not the case with natural herbal mouth rinses. Mouth rinse comes into direct contact together with your mucosa and may be absorbed directly into your bloodstream. Mint which is a perennial plant has antimicrobial property and can be used as a mouth wash for these patients. Aim: To evaluate the efficacy of aqueous extracts of Mint on Candida albicans and Streptococcus mutans by evaluating their zone of inhibition. Methodology: Cell suspension with 108 cells were prepared using candida albicans and Streptococcus mutans. Using sterile micro tip, wells were made which was about 8mm in diameter. Lawn culture was made on appropriate media.

Study of Antioxidant Effects of Alcoholic Extract of Mentha longifolia on Fat Oxidation of High-Consumption Meat Products in Tabriz

Background: Fat peroxidation is one of the problems in food processing, cooking, and storage. Oxidative changes cause pathological effects in biological systems and reduce the taste and quality and ultimately spoil food. Using aromatic plants and vegetables with antioxidant properties can play an important role in preventing these adverse effects. The antioxidant effects of Mentha longifolia have been considered in recent years.This study aimed to investigate the antioxidant activity of the peppermint plants and determine its protective effect on lipid oxidation of high-consumption meat products in Tabriz. Methods: To this end, aqueous-alcoholic extract of mint leaves and twigs with concentrations of 0.1%, 1%, 5% with homogeneous mixtures of 10%, 90% meat hamburger products, and 45% sausages were exposed. Lipid oxidation was measured by measuring malondialdehyde using the TBARS method on day 0 and after 42 days of exposure to peppermint extract at 0-4 °C and was compared with the control group. Results: The results showed that increasing the shelf life of meat mixtures significantly increases fat peroxidation (P = 0.05). Also, increasing the concentration of peppermint extract in meat solution samples significantly reduces the amount of malondialdehyde (P = 0.05). The results showed the antioxidant activity of peppermint during the storage time of meat products and its benefits can be used in the food industry. Conclusion: The present study showed that peppermint extracts have strong antioxidant activity and can be used in food and biological systems and can be used as a substitute for synthetic antioxidants to reduce their harmful effects on health.

Introducing Three New Fruit-Scented Mints to Farmlands: Insights on Drug Yield, Essential-Oil Quality, and Antioxidant Properties

Mint species are one of the most traded medicinal plants with a wide array of applications in the food, pharmaceutical, and perfumery industries. Here, a field experiment based on completely randomized block design (RCBD) aimed to compare drug yield, antioxidant properties, and essential-oil (EO) quality of three newly introduced mints (i.e., ginger mint, pineapple mint, and grapefruit mint) with a chiefly cultivated one (i.e., peppermint). The results manifested that dry-weight yield and EO yield of grapefruit mint (310 g/m2 and 5.18 g/m2, respectively) was approximately 2 times more than that of others. The highest EO content (i.e., 3.12%, v/w)) was obtained from the ginger mint; however, there were no significant differences among the other three mints. The highest total flavonoids content and 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity of both methanolic and ethanolic extracts were found in pineapple and grapefruit mint. Methanolic extract of ginger mint yielded the highest total polyphenol content, whereas the ethanolic extract of pineapple mint showed the highest total polyphenol content. According to mean comparisons, the EO of ginger mint exhibited the highest antioxidant activity (EC50 value = 2.23 µL/mL), while EO of peppermint showed the lowest antioxidant activity (EC50 value = 48.23 µL/mL). Gas chromatography analysis identified four EO types among these mints: (i) grapefruit mint EO rich in linalool (51.7%) and linalyl acetate (28.38%); (ii) ginger mint EO rich in linalool (59.16%); (iii) pineapple mint EO rich in piperitone oxide (77.65%); and (iv) peppermint EO rich in menthol (35.65%). The findings of the present study provide new insights into the cultivation of preferable mints possessing desired characteristics for food and drug industries.

Pectin-containing phytodrinks of adaptogenic action as an essential factor of development of sustainable systems of agrarian-and-food production

This article presents the results of research on samples of raw materials for the production of phytodrinks: hawthorn, Chinese lemongrass, rosehip, mountain ash, a mixture of mint and thyme leaves. The content of pectin substances, vitamins, micro and macronutrients, and the mass concentration of polyphenolic compounds were determined. Based on the obtained data, phytodrinks of the PHYTO PECTO series were developed and studied, containing liquid apple pectin, extracts from the studied fruits, stevia extract, mint and thyme leaf extract. The obtained results prove that the developed samples of phytodrinks contain a high amount of biologically active compounds and can be recommended for the diet of modern humans.

Hydrogel films of methanolic Mentha piperita extract and silver nanoparticles enhance wound healing in rats with diabetes Type I

Poor wound healing is considered an obstacle in diabetics, which requires effective therapy. Our goal was to investigate the combined effect of mint and silver nanoparticle hydrogel films as wound-healing agents in diabetic rats. Thirty rats were arranged into five groups. The hydrogel films were prepared through an eco-friendly method, excluding toxic solvents and diluents. Gel 1 and fucidin showed complete wound-healing effect on the 22nd day, while Gel 2 showed a faster effect on the 16th day, all compared to group 1 which healed in 25 days. Diabetic rats in group 2 healed beyond 25 days. Moreover, Gel 1 and Gel 2 decreased the fasting blood glucose. Gel 2 enhances wound healing in diabetic rats via multiple mechanisms of action, possibly due to the ability of mint and silver nanoparticles to sustain their concentration at the wound site with limited toxicity. Abbreviations: CO: castor oil; CS: corn starch; DIW: deionized water; H: hydrogel film; H-MME: hydrogel film developed with CS, PVA, CO and MME; H-SMME: hydrogel film developed with CS, PVA, CO and MME/ SNP; MME: methanolic mint extract; PVA: polyvinyl alcohol; SNP: silver nanoparticles; STZ: streptozotocin

DPPH Assay and Reducing Power Activity ofWater Extract of (Mentha longifolia) Mint

Antioxidative properties of plants may be associated with oxidative stress defence in different human diseases. Oxidative stress and free radicals can be neutralized by antioxidants which are of great significance in preventing the expansion of these diseases. Many studies have investigated the toxic effect of synthetic antioxidants, thus to avoid these toxic effects new antioxidants of natural origin have been deliberated in recent years. Mint (Mentha longifolia) is extensively used as medicine, spice, food and flavouring. In the current work, an aqueous extract of mint leaves was determined using the DPPH assay and reducing power activity. Strapping and sound antioxidant effects were observed in 2,2-diphenyl-1- picrylhydrazyl radicals at concentrations of 0.1-0.5 mg/ml, ranging from 20.32 ± 0.35 % to 65.75 ± 1.5 %, while standard antioxidant BHT possess % Inhibition (DPPH) 30.41 ± 0.65 % to 83.50 ± 2.3 % at same concentration. A similar effect was found in the reducing power assay, which exhibited absorbance of M. longifolia water extract ranging from 0.1501 ± 0.010 to 0.5845 ± 0.042 and BHT exhibited 0.3221 ± 0.026 to 0.8197 ± 0.124 at 700 nm. The conclusion recommends that M. longifolia has confirmed vital benefits due to high concentration of antioxidants and has vast impending for claim in the preparation of useful food entities.

FORMULATION AND IN VITRO EVALUATION OF ETHANOLIC EXTRACT OF POLYHERBAL FACE CREAM

Objective: The aim of the present research work was to formulate and evaluate polyherbal face cream using ethanolic extracts of Aloe Vera gel, Neem, Turmeric and Mint.
 Methods: Extraction was done by the cold maceration technique. The cream was prepared by using the slab technique for homogeneous mixing of all the excipients and the herbal extracts. Three formulations of Oil in Water (O/W) type herbal cream were developed, namely F1, F2, and F3.
 Results: All the formulations were evaluated for various physical characteristics viz. pH 6.1-6.3, Spreadability 5-7.5gcm/sec, Viscosity 591-638 Cps, Extrudibility 2564-5102 g/cm2, good appearance and no phase separation was observed. Based on the results, F1 was found to be an optimized formulation with a smooth texture, good spreadability, extrudability and adequate viscosity. Stability studies as per ICH (International Council on Harmonisation) guidelines, revealed that the optimized formulation was stable at 25 °C±1 °C and 6% RH.
 Conclusion: Based on the results and discussion, the prepared formulations were found to be yellow in colour with a pleasant odour and smooth texture. All the formulations had almost constant pH, homogenous, emollient and non-greasy. As single plant extract possibly cannot increase the extent of efficiency of medicinal and cosmetic property compared to polyherbal plant extract. Considering that, we mixed polyherbal extracts to improve the cosmetic properties of the prepared polyherbal face cream. Hence it can be concluded that the cream was stable and can be safely used topically.

Anesthetic Pharmacology of the Mint Extracts L-Carvone and Methyl Salicylate

Introduction: Hydrocarbons with sufficient water solubility allosterically modulate anesthetic-sensitive ion channels. Mint extracts L-carvone and methyl salicylate water solubility exceeds modulation cutoff values for γ-amino butyric acid type A (GABAA) receptors, N-methyl-D-aspartate (NMDA) receptors, and type-2 voltage-gated sodium (Nav1.2) channels. We hypothesized that mint extracts modulate these channels at concentrations that anesthetize rats. Methods: Channels were expressed separately in frog oocytes and studied using 2-electrode voltage clamp techniques at drug concentrations up to 10 mM. Normalized current effects were fit to Hill equations. Mint compounds were formulated in a lipid emulsion and administered IV to rats. When unresponsive to the tail clamp, rats were exsanguinated, and plasma drug concentrations were measured. Results: Both mint compounds caused concentration-dependent inhibition of all channels except for methyl salicylate which inhibited GABAA receptors at low concentrations and potentiated at high concentrations. Plasma drug concentrations in anesthetized rats were 7.9 mM for L-carvone and 2.7 mM for methyl salicylate. This corresponded to ≥53% NMDA receptor inhibition and ≥78% Nav1.2 channel inhibition by both compounds and 30% potentiation of GABAA receptors by methyl salicylate. Conclusion: L-Carvone and methyl salicylate allosterically modulate cell receptor targets important to molecular actions of conventional anesthetics at concentrations that also induce general anesthesia in rats.

Design of an Artificial Intelligence of Things Based Indoor Planting Model for Mentha Spicata

In recent years, many large-scale plantings have become refined small-scale or home plantings. The rapid progress of agriculture technologies and information techniques enables people to control the growth of agricultural products well. Hence, this study proposes an Artificial Intelligence of Things (AIoT) based Plant Pot Design for planting edible mint in an office setting, which is called APPD. APPD is composed of intelligent gardens and a cloud-based service platform. An intelligent garden is deployed an Arduino with multiple sensors to monitor and control plant pots of the edible mint, Mentha spicata. The cloud-based service platform provides a Case-Based Reasoning (CBR) inference engine with a database for adjustment influence factors. This study discusses eight growing statuses of Mentha spicata with different illumination, photometric exposure, and moisture content, designed for an office environment. Evaluation results indicate that Mentha spicata with 16 h red–blue lighting and 50% moisture content makes a maximum 5% mint extract of the total weight of the mint leaves. Finally, APPD can be a reference model for researchers and engineers.

A comparative study to evaluate the effectiveness of raw ginger and mint extract on dysmenorrheal symptoms among nursing students of selected nursing college, Hubballi

A comparative study to evaluate the effectiveness of raw ginger and mint extract on dysmenorrheal symptoms among nursing students of selected nursing college, Hubballi

In vitro antioxidant and antimicrobial activities of herbal combinations of Rosemarinus officinalis (rosemary) and Mentha piperita (peppermint)

Herbal products are of interest to many patients and health care practitioners as about 70% of population worldwide rely on herbal medicines for part of their primary health care. When herbs are used in combination, the effects can be complicated as various interactions can occur among the individual components. The most desirable interactions are those which can result in additional therapeutic benefit. The present study aims at investigating the antioxidant and antimicrobial potentials of herbal combination of Rosemary and Mint extracts. This study was conducted to investigate the relationship between total phenolic content, antioxidant activity and antimicrobial properties of different herbal combinations. Our results demonstrated the antioxidant potential of herbal combination of hydroalcoholic extract of Rosmary:Mint::70:30 was highest and Rosemary:Mint::10:90 was lowest. Similarly antibacterial effect was maximally exhibited by Rosemary:Mint::70:30 combination and minimally exhibited by Rosemary:Mint::10:90 using two Gram positive and Gram negative strains. Our results suggested that hydroalcoholic extracts of Rosemary:Mint in the ratio of 70:30 had highest antioxidant potential and antibacterial property. Hence this combination is best suited for further analysis.

Development of functional caramel using system packages MathLab

The article presents substantiation for expanding the market for functional food products, in particular, confectionery - caramel. Proper nutrition is an integral part of a modern person diet; due to their properties, they increase the immunity and immune status of a person. The aim of the work is to create composite mixtures for sugar-free caramel using modern software. The studies were carried out using the MathLab software package, in particular the Statistica 10.0 software. A methodology for creating recipes using system packages has been developed. To enrich the caramel, the following components were selected: apple juice, coltsfoot extract, orange juice, mint and burdock extract, cranberry and lingonberry juices. An optimal recipe has been designed and equations are presented for calculating the dosages of the components of the enriched sugar-free caramel based on a natural sweetener isomalt with the addition of plant-based additives containing macro and micronutrients necessary for the normal functioning of the human body with a diagnosis of type II diabetes mellitus.

Коррекция тревожных расстройств у детей, перенесших новую коронавирусную инфекцию

Background: currently, the term "post-COVID conditions" has been commonly used in healthcare practices. It includes impairments of multiple human organ systems. Many international and Russian researchers have mentioned in their studies that such patients, including children, are at a higher risk of developing psychoneurological disorders. Aim: to assess the clinical efficacy of a syrup, containing choline, glycine, lysine, B vitamins, zinc, magnesium, lemon balm and mint extracts to cope with the manifestations of anxiety disorders developed in children after COVID-19 infection. Patients and Methods: this prospective study involved 65 children, 7–11 years old, who had mild cases of COVID-19 and developed manifestations of anxiety disorders. All patients were given recommendations including nutritional therapy, sleep and rest routine, walking into the fresh air, and limiting the time children spend on their phones, computers and TV. 40 patients, 20 of whom were girls, of the treatment group (TG) additionally received a biologically active supplement (BAS), "Kidz Syrup with lemon balm and mint", at the dosage of 1 stick (5 ml) 3 times a day for 42 days. 25 children, 16 of whom were girls, were included in the control group (CG), receiving only routine treatment. The duration of follow-up period was 42 days. A questionnaire was filled out by children’s parents to assess the severity of asthenic syndrome. Results: after one month of treatment with the BAS added to the routine therapy, the TG patients demonstrated trends in lower severity of all symptoms of asthenic syndrome vs that at the baseline (р<0.05, unpaired t-test). Such trends were not reported in the control group (р>0.05, unpaired t-test). Parents of the TG children reported more physical activity and interest, better sleep and appetite, normalizing kids’ behavior and improving relationships. In the CG patients, receiving routine therapy, these changes were less pronounced. Seven of 40 patients did not like taking the syrup because of the unpleasant syrup taste. It was the reason why three of 40 patients declined further participation in the study. None of the children reported allergic reactions. Conclusion: a biologically active substance "Kidz syrup with lemon balm and mint" given to the primary school-aged children who survived COVID-19 and developed manifestations of anxiety disorders, helps to improve their ability to manage emotional distress, concentrate attention and memory, and has the protective effect against the increasing mental burdens. KEYWORDS: children, COVID-19, post-COVID conditions, anxiety disorders, biologically active supplement, lemon balm and mint. FOR CITATION: Sagitova G.R., Shuldais V.A., Klyueva N.V. et al. Management of anxiety disorders in children who survived the novel coronavirus infection. Russian Journal of Woman and Child Health. 2022;5(4):340–345 (in Russ.). DOI: 10.32364/2618-8430-2022-5-4-340-345.