Development of rational methods for creating ordered two-dimensional (2D) structures with nanometer scale precision is one of the central issues in the nanoscience and nanotechnology fields because of their intrinsic physical-chemical properties which are seen in those of their equivalent bulk state. Inclusion of highly regulated nanopores into the nanosheet structure will further open the possible applications such as nanosieves, molecular/ion storage and sensor devices as well as introducing guest molecules into the nanopores tune variedly the sheet properties (electric conduction, nanoheterojunction). Utilizing molecular building units are suitable for creating such porous nanosheets because of rich variety of design and facile modification of size and shape.Here, I present a facile bottom-up synthesis of molecular nanosheets with both positional and size regulated nanopores utilizing air/liquid interfaces[1-5]. By applying liquid interfaces, growth direction of the object can be well controlled with utilizing self-assembly feature of the molecules under mild conditions. We have succeeded to tune finely the nanosheet structures by rational modification of molecular building units . The highly crystalline structure remains after transferring a solid substrate from the liquid surface as well as without any supports. Notably, such highly oriented porous crystalline structure is obtained specifically by applying bottom up synthesis at air/liquid interfaces, not by other techniques.I also present detailed insights into the formation process of electrically conductive MOF nanosheets composed of 2,3,6,7,10,11-hexaiminotriphenylene (HITP) and Ni(II) ions (HITP-Ni-NS) at the air/liquid interface [6-8]. The morphological and structural features of HITP-Ni-NS strongly depend on the standing time—the time without any external actions involved, but leaving the interface undisturbed after setting the ligand solution onto the metal-ion solution. We find that the fundamental features of HITP-Ni-NS are determined by the standing time with conductivity sensitively influenced by such pre-determined HITP-Ni-NS characteristics. These findings will lead towards the establishment of a rational strategy for creating MOF nanosheets at the air/liquid interface with desired properties, thereby accelerating their use in diverse potential applications.1. R. Makiura et al. Nature Mater. 9, 565 (2010).2. S. Motoyama, R. Makiura, O. Sakata, H. Kitagawa, J. Am. Chem. Soc. 133, 5640 (2011).3. R. Makiura, O. Konovalov, Sci. Rep. 3, 2506 (2013).4. R. Makiura et al. ACS Nano, 11, 10875–10882 (2017).5. R. Makiura et al, Coord. Chem. Rev. 469, 214650 (2022).6. R. Makiura et al, ACS Appl. Mater. Interfaces, 13, 54570 (2021).7. R. Makiura et al, J. Colloid Interface Sci. 651, 769 (2023).8. R. Makiura et al, Langmuir. 39, 8952 (2023). Figure 1
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