At the beginning of the fourth wave of memory studies, the relationship with design appears poorly explored, although the memory project is fundamental for the contemporary and interdisciplinary past reframing. From this perspective, the article proposes an intrinsic but not yet evident link between memory studies and communication design for the territory, a young discipline that has taken up the “stratified place” as its own specific dimension, focusing on its valorization and visual translation. This novel connection is highlighted by the mnemotopic approach in which place and memory coexist in a unique meaning formation, supporting the remembrance of the territorial experience. Through a lexical transfer of the term mnemotope, generally used in other fields of knowledge (e.g. cultural anthropology), to design, it becomes a performative concept integrated into processes and artifacts as an active part of project development. The mnemotope as a plural object of territorial interpretation, sailing from Nora’s lieux de memoire, passing through Assmann’s cultural memory reflections, and landing in communication design, can be adopted as an alternative interpretative criterion that not only proposes a resematization of the memory of places but can be considered as a real medium for exploring the past that can also operate on a didactic level by being included in experimental design courses. In this context, the article will show how the mnemotopic approach has been developed during my personal doctoral journey and pedagogically implemented by the DCxT research group of the Design Department of Politecnico di Milano.