This article talks about position of the EU in the Global politics, European integration process, EU challenges, such is refugees wave, Brexit, Ukraine and Syrian crisis, Russian foreign policy towards the EU, a new challenges after US president election. Мongolia’s tradional parners, Central and East European 8 states (Czech, Hungary, Latvia, Lithuania, Estonia, Poland, Slovak and Slovenia) are were ready to join the EU in 2004. Romania and Bulgaria joined the EU from 1st, 2007 and Croatia in July 1st of 2013. By the enlargement of the EU, 15 members of state changed to 28 (after Brexit 27) and the EU comined population reached more than 500 million. The main root of the EU enlargement was to put European mutual interests in the first priority. Mongolia’s tradional partners East European countries that joined the EU can be beneficial to Mongolia’s export expansion, investments and the group that supports Mongolia from the EU. Mongolia and the EU partnership and cooperation: origins, development and expended, etc.,