Ethanol-water Solvent Research Articles

Effect of Ethanol on the Textural Properties of Whey Protein and Egg White Protein Hydrogels during Water-Ethanol Solvent Exchange.

This study aims at investigating the effect of ethanol (EtOH) on the textural properties of whey protein and egg white protein hydrogels. The hydrogels were produced by thermally induced gel formation of aqueous protein solutions. The water contained in the gel network was subsequently exchanged by EtOH to assess structural changes upon exposure of hydrogels to ethanolic aqueous phases. The textural properties of the hydrogel and alcogel samples were analyzed by uniaxial compression tests. For both protein sources, the hardness increased exponentially when pH and EtOH concentration were increased. This increase correlated with a shrinkage of the gel samples. The gel texture was found to be elastic at low EtOH concentrations and became stiff and hard at higher EtOH concentrations. It was found that the solvent exchange influences the ion concentration within the gels and, therefore, the interactions between molecules in the gel structure. Non-covalent bonds were identified as substantially responsible for the gel structure.

Effect of cyclodextrin types and reagents solvation on the stability of complexes between B-cyclodextrins and rutin in water-ethanol solvents

In this work, the solubility of rutin was first obtained in the water-ethanol solvents with small composition of co-solvent in the mixture at 25 °C. The results showed that the solubility of rutin improved with increasing ethanol content in the studied range 0–0.1 mol. fr. Solvation of hydroxypropyl-β-cyclodextrin in binary solvents was first studied by the method of interfacial distribution of the substance between two immiscible phases. It was found that when moving hydroxypropyl-β-cyclodextrin from water to the water-ethanol solvent, a decrease in the solvation of hydroxypropyl-β-cyclodextrin was observed. Complexation between rutin and β-cyclodextrin or hydroxypropyl-β-cyclodextrin was also studied in water and in the water-ethanol solvents. In the aqueous solution containing hydroxypropyl-β-cyclodextrin, the solubility of rutin was improved significantly and better than in the solution containing β-cyclodextrin. The stability of (rutin-hydroxypropyl-β-cyclodextrin) complex decreased with increasing the ethanol content and was determined by the sum of solvation of rutin (ΔtrGRuT) and hydroxypropyl-β-cyclodextrin (ΔtrGHPβCD). This effect was also observed for the complexation reaction between quercetin and hydroxypropyl-β-cyclodextrin in our previous study.

Investigation of the antimicrobial effects of Sapindus mukorossi on endodontic pathogens

Endodontic infections have a polymicrobial nature. Thus, eliminating the microorganisms from infected root canals without damaging healthy surrounding tissue is a major concern. Sapindus mukorossi (S. mukorossi) is a natural product with potential antimicrobial effects. The aim of this study was to evaluate whether various extract solutions of S. mukorossi have an antimicrobial activity against specific endodontic pathogens. Extracts were obtained from S. mukorossi fruit pericarps using methanol, ethanol, butanol and distilled water solvents. The inhibition zone, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) were determined with disc diffusion assay, broth microdilution assay and agar dilution assay. Antimicrobial inhibitory activity was observed with all four different solvent extracts of S. mukorossi against Fusobacterium nucleatum American Type Culture Collection (ATCC) 25586, Porphyromonas gingivalis ATCC 33277 and Actinomyces odontolyticus (clinical isolate). The MIC values were ranged 10.24-10.24, 0.01-0.64 and 1.28- 2.56 mg/mL, respectively. The MBC value was not detected for Fusobacterium nucleatum ATCC 25586. The MBC values were 0.02-1.25 and 2.56-5.12 mg/ mL for Porphyromonas gingivalis ATCC 33277 and Actinomyces odontolyticus (clinical isolate), respectively. Antifungal activities were also observed with the four different solvent extracts of S. mukorossi against Candida albicans ATCC 10231 and C. albicans clinical isolates 1, 2 and 3. The inhibition zone diameter values were in the range of 18-21 mm. The MIC values for C. albicans ATCC 10231 and C. albicans clinical isolates 1, 2 and 3 were 0.2-0.4 and MFC values were 0.4-0.8 mg/mL, respectively. The antimicrobial effects of the S. mukorossi fruit pericarp extract inhibited the growth of P. gingivalis, A. odontolyticus, F. nucleatum, and especially the C. albicans strains. S. mukorossi extract has interesting potential as an antimicrobial agent against endodontic pathogens.

The influence of Propylene glycol/Water and Ethanol/Water Binary Solvents on the in vitro Permeation of Garcinia mangostana L. Pericarp Extract across Shed Snakeskin

Garcinia mangostana pericarp (GMP) has antioxidant activity thus may be developed into a topical antioxidant formulation. This research aimed to study the topical delivery of GMP extract. Initially, some commonly used topical solvents, i.e., water and binary solvents of propylene glycol (PG)/water and ethanol/water (0; 10; 20 and 40%), were used to dissolve GMP extract and further tested on GMP extract in vitro skin permeation using shed snakeskin. The influence of solvents' effects was evaluated based on radical DPPH scavenging activity and expressed as radical scavenging activity equivalent GMP Extract (RSGMPE). The results showed that RSGMPE could be delivered into shed snakeskin. The extent of RSGMPE shed snakeskin retention was similar among water and all PG/water or ethanol/water binary solvents. RSGMPE was also found in the receptor phase from all PG/water binary solvents, whereas that from ethanol/water solvents only shown from 20% ethanol/water solvent even though all ethanol-water solvents produced significantly higher RSGMPE compared to water and PG/water binary solvents

Improvements in hydrogen production from methane dry reforming on filament-shaped mesoporous alumina-supported cobalt nanocatalyst

The mesoporous gamma-alumina (γ-Al2O3) synthesized via evaporation-induced self-assembly method (EISA) using inorganic salt, Al(NO3)3·9H2O precursor and water-ethanol solvent mixture was implemented as a support for Co catalyst in methane dry reforming at 973–1073 K under 1 atm. The γ-Al2O3 support possessed filament-shaped morphology with surface area of 173.4 m2 g−1 and cobalt nanoparticles were successfully dispersed on support with small crystallite size of 7.8 nm. The stability of 10%Co/Al2O3 was evident for CH4 and CO2 conversions at 1023 and 1073 K. CH4 conversion could reach to 76.2% while 81.6% was observed for CO2 conversion at 1073 K. Although graphitic and amorphous carbons were unavoidably formed on used catalyst, 10%Co/Al2O3 exhibited an outstanding performance comparable to noble metals with the desired ratio of H2/CO for downstream Fischer-Tropsch process.

Host–guest inclusion complex of β-cyclodextrin and benzoic acid in water–ethanol solvents: spectroscopic and thermodynamic characterization of complex formation

In this study, an inclusion complex of benzoic acid with β-cyclodextrin (BA-βCD) was obtained from water–ethanol solvents. The yield of complex synthesis in binary mixtures is greater than in water and reaches maximum value at 0.10 mol fraction of ethanol. Results of FTIR spectroscopy analysis showed that the main difference in the spectra of the acid and inclusion complex was observed in the frequency ranging from 2500 to 3100 cm−1, corresponding to aromatic hydrogen vibrations. These vibrations are highly attenuated in complex. Phase solubility and differential scanning calorimetry studies revealed that the inclusion complex was obtained with 1:1 stoichiometric ratio and the solubility of benzoic acid increased with an increase in β-cyclodextrin concentrations in water. The logarithm of stability constant in water was found to be lgK = 1.99. The thermodynamic parameters for the reaction of (BA-βCD) complex formation in H2O–EtOH solvents were determined from calorimetric experiments carried out by means of the calorimetric titration system TAM III (TA Instruments) at T = 25 °C. The heat effects of mixing β-cyclodextrin solutions with benzoic acid were obtained from water–ethanol mixed solvents containing X(EtOH) = (0.00, 0.10, 0.20 and 0.30) mole fraction at pH = 3.6 and T = 25 °C. However, at X(EtOH) = 0.30 mol fraction, according to the calorimetric titration data, no complex formation occurs. When transferring from H2O to H2O–EtOH solvents, complex stability decreases from lgK = 2.4 to lgK = 0.7, wherein the reaction exothermicity increases from − 12.2 kJ mol−1 to − 44.3 kJ mol−1. An increase in the exothermicity of complexation is accompanied by a decrease in the entropic contribution to the change in the reaction Gibbs energy.

Evaluation of Reverse Osmosis Membranes in Concentration of Beetroot Peel Extract

Recovery of valuable products from organic wastes with conventional extraction method plus modern separation technology is becoming popular in solid waste management. The major attention of this project was to test the efficiencies of two different types of reverse osmosis membranes (RO99 and X20) on juice concentration extracted from peel of beetroot which is "waste". The extractions of beetroot peel were completed using water and ethanol-water (15 v/v%) solvents at 22 °C for 60 minutes. The applied transmembrane pressure, temperature, and recirculation flow rate of membrane separation process were 40 bars, 30 °C, and 400 L/h, respectively. Quantifications of valuable compounds were detected using spectrophotometer. The permeate flux profiles were investigated and lower permeate flux was experienced with RO99 compared to X20 in both methods. Additionally, from the aspect of efficiency, RO99 outstripped X20 membrane on concentration of some compounds such as betalains, and phenolic components. Betaxanthin, betacyanin, antioxidant and TPC contents in final retentates of RO99 membrane concentration were as follow: 292.47±1.93 mg/L, 499.03±1.3 mg/L, 1133.15±25.74 mg/L,1243.96±106.56 mg/L (water solvent) and 337.26±4.31 mg/L, 585.2±5.83 mg/L, 698.55±22.53 mg/L, 1268.87±48.69 mg/L (ethanol-water solvent), respectively. From this experiment, expectation can be made that membrane technology can widen its applications in food and pharmaceutical industries.

Hydrogen-Bonding Interactions in Hybrid Aqueous/Nonaqueous Electrolytes Enable Low-Cost and Long-Lifespan Sodium-Ion Storage.

Although "water-in-salt" electrolytes have opened a new pathway to expand the electrochemical stability window of aqueous electrolytes, the electrode instability and irreversible proton co-insertion caused by aqueous media still hinder the practical application, even when using exotic fluorinated salts. In this study, an accessible hybrid electrolyte class based on common sodium salts is proposed, and crucially an ethanol-rich media is introduced to achieve highly stable Na-ion electrochemistry. Here, ethanol exerts a strong hydrogen-bonding effect on water, simultaneously expanding the electrochemical stability window of the hybridized electrolyte to 2.5 V, restricting degradation activities, reducing transition metal dissolution from the cathode material, and improving electrolyte-electrode wettability. The binary ethanol-water solvent enables the impressive cycling of sodium-ion batteries based on perchlorate, chloride, and acetate electrolyte salts. Notably, a Na0.44MnO2 electrode exhibits both high capacity (81 mAh g-1) and a remarkably long cycle life >1000 cycles at 100 mA g-1 (a capacity decay rate per cycle of 0.024%) in a 1 M sodium acetate system. The Na0.44MnO2/Zn full cells also show excellent cycling stability and rate capability in a wide temperature range. The gained understanding of the hydrogen-bonding interactions in the hybridized electrolyte can provide new battery chemistry guidelines in designing promising candidates for developing low-cost and long-lifespan batteries based on other (Li+, K+, Zn2+, Mg2+, and Al3+) systems.

The microstructure and magnetic properties of yttrium iron garnet film prepared using water-alcohol solvents

This study reports on the preparation of yttrium iron garnet thin films using three different solvents via a sol-gel method, followed by a spin coating technique and an annealing process at 750 °C for 2 h in the air. The three different solvents were water-ethanol, water-methanol and water. The microstructure analysis using an X-ray diffractometer revealed that the films prepared using a water-alcohol solvent crystallized into YIG single phase at a low annealing temperature (750 °C). The film thicknesses are in the range of 200 nm to 400 nm. The film prepared using a water-ethanol solvent has the smallest crystallite size. All films are soft ferrimagnetic at room temperature and the film prepared using a water-ethanol solvent exhibits the highest saturation magnetization value (162 emu/cm3).

AKTIVITAS ANTIOKSIDAN KECIBELING, BAKAU MERAH, DAN KATUK PADA METODE EKSTRAKSI DAN RASIO EKSTRAK YANG BERBEDA

<em></em><em><em>Indonesian medicinal plants, such as </em>Strobilanthes crispa<em> (L.) Blume (locally known as kecibeling), red mangrove (</em>Rhizophora stylosa<em> Griff.) and star gooseberry {</em>Sauropus androgynus<em> (L.) Merr.} contain active compounds that act as antioxidants. The study aimed to determine the effect of extraction methods (maceration and infusion) on the antioxidant activity of both single extract and several combination ratios of the extracts mixture of kecibeling leaves, red mangrove leaves and star gooseberry stems. Dried powdered of the samples of a 40 mesh size were extracted using 96 % ethanol solvent (maceration method) and water solvent (infusion method). A single extract or a combination of the three-single extracts (1: 1: 1; 1: 1: 2; 1: 2: 1; and 2: 1: 1) were then evaluated for their antioxidant activity based on the free radical method 2,2-diphenyl-1-picrylhydrazyl (DPPH). In general, extraction method using ethanol (maceration) was better than water (infusion). Antioxidants activities from ethanol extracts of the kecibeling leaves showed the strongest activity with an inhibitory concentration (IC<sub>50</sub>) value of</em> <em>37.65 ppm than the infusion extracts. The combination of a single ethanol extract from the three plants at a ratio of 2: 1: 1 was synergistic, which indicated by its strongest antioxidant activity (IC<sub>50</sub> = 18.78 ppm). However, it still below the antioxidant activity of vitamin C (IC<sub>50</sub> = 4.24 ppm). Ethanol extract of kecibeling leaves singly or combined with the ethanol extracts of red mangrove leaves and star gooseberry stems can be developed as a potential antioxidant.</em><br /></em>

Micellization and Solvation Properties of Newly Synthesized Imidazolium- and Aminium-Based Surfactants

This work aimed to study the solvation properties of newly synthesized cationic surfactants: 1-hexyl-1-methyl-1H-imidazol-1-ium bromide (R6Im), 1-dodecyl-1-methyl-1H-imidazol-1-ium bromide (R12Im), N,N,N-tributylhexan-1-aminium bromide (R6N4), and N,N,N-tributyldodecan-1-aminium bromide (R12N4) in water and ethanol–water solvents with a 0.237 mole fraction of ethanol at 298.15 K using conductivity, refractive index, surface tension, and density measurements. Critical micelle concentration (CMC) for the synthesized surfactants was determined and discussed. Thermodynamic parameters including association constant, molal volume, and polarizability were calculated and discussed. Some surface properties of surfactants including excess surface concentration and minimum area per molecule were also calculated and discussed. A good agreement was found between the CMC values obtained from different techniques, such as conductivity, refractive index, and surface tension. Imidazolium surfactants had been proved to decrease the CMC and increase the association constant with the increase of ethanol mole fraction, while tributylamine had been proved to increase the CMC and decrease the association constant with the increase of ethanol mole fraction. Also, imidazolium surfactants had been proved to have higher CMC than tributylamine, which may be related to higher solvation of imidazolium surfactants than that of tributylamine. Both surfactants (R12Im) and (R12N4) were proved to have lesser CMC.

The Effect on Composition of EtOH : H2O Solution on the Stability of Cobalt(II) Glycylglycinate Complexes

The stability constants of cobalt(II) glycylglycinate complexes in water–ethanol solvent of variable composition are determined potentiometrically at 298 K and an ionic strength of the solutions (NaClO4) of 0.1. The stability of cobalt(II) complexes with glycylglycinate ion is found to increase with ethanol content in the solution. The resulting stability constants of cobalt(II) glycylglycinate are compared to the literature data on the stabilities of nickel(II) and copper(II) complexes with glycylglycine ion. The contributions of resolvation of the reagents to changes in the Gibbs free energy of cobalt(II) glycylglycinate formation in water–ethanol solvent are evaluated. The increase in stability of the complexes with glycylglycinate ion is mainly caused by weakening of ligand solvation as one proceeds from water to water–ethanol solvents.

Analysis of Mineral Compound of Plant Anthemis pseudocotula Boiss with Different Solvents by Ion Chromatography

This aim of this study was to determine the mineral contents in the plant of anthemis pseudocotula boiss with several solvents by Ion Chromatography , that the plant Anthemis pseudocotula Boiss commonly native and collected from their natural place from Hawdian’s village soran/Erbil, North Iraq.The extract of five solvent as (distilled water, ethanol, distilled water: ethanol, hexane: ethanol and hexane) with both technique of microwave and conventional extraction. It was shown that fifteen mineral ion compounds were identified in the suppressed IC technique. Our results were detected eight mineral ions as (F, Cl-, PO 4 +, SO 4 +, NH 4 , K+, Mg and Ca+) from 15 ions in our plant according to solvent extract and method technique. The concentrations of mineral ion compounds were the results showed high amounts of K+ (71.370ppm), Ca+ (71.420ppm), PO 4 + (24.164ppm), SO 4 + (28.127 ppm), Cl- (17.548 ppm) and Mg (10.279ppm) were found by microwave extraction with distilled water and ethanol with other solvents respectively. Furthermore, the results showed that mineral values of the K+ (43.277 ppm), SO 4 + (26.761 ppm), Cl- (18.028 ppm) were high concentration by conventional extraction with distilled water and water-ethanol solvents, respectively. These results were compatible with quantitative measurements. This study showed that the technique of microwave with distilled water and ethanol: distilled water solvents were important for the minerals content of Anthemis pseudocotula Boiss, a precious plant.

Solubility measurement and thermodynamics modelling for potassium dihydrogen phosphate in a water-ethanol system from 293.2 to 323.2 K

The phase equilibrium and thermodynamic properties of potassium dihydrogen phosphate (KDP) in the binary water-ethanol system are of critical significance for the salting-out crystallization of KDP production using ethanol as anti-solvent. The solubility of KDP in water-ethanol solvent was determined by the static equilibrium method under constant pressure at temperatures ranging from 293.2 to 323.2 K, with the molar fraction of water varying between 0.3885 and 1.0. The solubility of KDP significantly decreased with the addition of ethanol and increased with rising temperature. A new group of parameters (middle-range interaction) of the mixed-solvent electrolyte model (MSE model) of KDP in the water-ethanol system were obtained by regressing all experimental solubility data. The MSE model with the newly acquired parameters was successfully used to simulate the KDP precipitation process in KH2PO4/C2H5OH/H2O systems and could predict the distribution of ion speciation and activity coefficients. This paper provides fundamental thermodynamic properties and a prediction model for the anti-solvent crystallization process for KDP production.

Ethanol addition during aqueous phase recirculation for further improving bio-oil yield and quality

The increase of nitrogen content caused by the re-polymerization of nitrogenous compounds remains an important challenge during aqueous phase recirculation in the water solvent. In this work, aqueous phase recirculation was conducted in the ethanol-water solvent to evaluate the feasibility of ethanol addition in inhabiting the re-polymerization of nitrogenous compounds. The present study provides a comprehensive comparison of yield and quality between bio-oils derived from aqueous phase recirculation in the water solvent and ethanol-water solvent. The results showed that the addition of ethanol in aqueous phase recirculation displayed higher promotion in bio-oil yield (7%) compared with water solvent (3.55%). The energy recovery efficiency of bio-oil from ethanol-water solvent reached 87.43% after recirculation for three times, while that from the water solvent was 74.61%. The elemental analysis and gas chromatography-mass spectrometry analysis indicated that ethanol addition could inhibit the re-polymerization of nitrogenous compounds and thus decrease the nitrogen content in bio-oil. This resulted in lower NO and HCN emission peaks during the combustion process. Besides, the addition of ethanol increased the content of light molecular weight fractions and decreased the coke formation, which contributed to complete combustion and resulted in lower CO emission peaks. Overall, this work provides a feasible way for further improving the bio-oil yield and fuel quality through ethanol addition in solvent during aqueous phase recirculation.

Impact of heat treatment on anti-oxidative and anti-colon cancer activities of the soluble extracts from black mulberry (Morus nigra L.) using water and ethanol-water solvents.

Black mulberry (Morus nigra L.) is an edible fruit with various health functions in the body. In this study, the lyophilized black mulberry was extracted using water and 75% (v/v) ethanol–water, respectively; afterwards, the soluble extracts were subjected to these treatments like ethanol removal, heat treatment at 100 °C for various times, or activated carbon-mediated dephenolization. The assaying results indicated that the used heat treatment led to decreased anthocyanin but increased total phenol and flavonoid contents for the water- and ethanol-extracts, while the dephenolized extracts after the heat treatment also had increased total phenol and flavonoid contents. The performed heat treatment decreased anti-oxidative activities of the water- and ethanol-extracts, resulting in reduced scavenging activities to the DPPH and hydroxyl radicals and lower reducing power for Fe(iii) ions. However, the results from cell experiments also demonstrated that the heat treatment at 100 °C for 45 min caused the water- and ethanol-extracts or dephenolized extracts with higher anti-cancer activity against human colon cancer HCT-116 cells. Overall, the heated extracts were more effective than the unheated counterparts to inhibit cell growth, alter cell morphology, generate more intracellular reactive oxygen species, enhance intracellular Ca2+ level, and reduce mitochondrial membrane potential of the cells. It is thereby concluded that the heat treatment of black mulberry might reduce its anti-oxidation but increase its anti-colon cancer effect due to the occurrence of the Maillard reaction and other unidentified reactions, which will deepen our present knowledge and provide a scientific basis to optimize storage or processing conditions of plant-based foods.

Thermodynamic Characteristics of the Resolvation of Glycylglycinate Ions and Their Contribution to the Change in Stability of Complexes with Cu(II) and Ni(II) in Aqueous–Organic Solvents

Thermodynamic characteristics (∆G, ∆Н, T∆S) of the resolvation of glycylglycine and its protonated and deprotonated forms in aqueous solutions of ethanol and dimethylsulfoxide are presented experimentally and calculated on the basis of original and literature data. The change in the Gibbs energy of the reactions of the formation of nickel(II) and copper(II) glycylglycinate complexes in water-ethanol and water-dimethylsulfoxide solvents is considered, and the solvation contributions of the reagents to the change in the stability of complex particles are estimated. Features of the changes in the thermodynamic characteristics of the solvation and complexing of glycylglycinate ions with d-metals in aqueous–organic mixtures are described.

Electrophoretic deposition of polymethylmethacrylate and composites for biomedical applications

For the first time, an electrophoretic deposition (EPD) method has been developed for the deposition of polymethylmethacrylate (PMMA) and PMMA-alumina films for biomedical implant applications. The proposed biomimetic approach was based on the use of a bile salt, sodium cholate (NaCh), which served as a multifunctional solubilizing, charging, dispersing and film-forming agent. Investigations revealed PMMA-Ch− and PMMA-alumina interactions, which facilitated the deposition of PMMA and PMMA-alumina films. This approach allows for the use of a non-toxic water-ethanol solvent for PMMA. The proposed deposition strategy can also be used for co-deposition of PMMA with other functional materials. The PMMA and composite films were tested for biomedical implant applications. The PMMA-alumina films showed statistically improved metabolic results compared to both the bare stainless steel substrate and pure PMMA films. Alkaline phosphatase (ALP) activity affirmed the bioactivity and osteoconductive potential of PMMA and composite films. PMMA-alumina films showed greater ALP activity than both the PMMA-coated and uncoated stainless steel.

Cost-effective production of organosolv lignin from woody biomass using ethanol-water mixed solvent at mild conditions

A cost-effective process has been developed for fractionating pine sawdust into lignin and cellulose fractions in an ethanol-water mixed solvent. The effects of temperature, different types of catalysts (i.e., strong acid, weak acid and alkali), and residence time, with respect to yields and purity of the crude lignin (degraded products) and crude cellulose (solid residue) were investigated. It is found that the purity of crude lignin was higher but with a lower product yield under a weak acid or alkali catalysis in comparison to strong acid treatments. According to the analysis results, the optimal conditions for fractionation process were as follows: a mixed solvent of ethanol-water (1:1, v/v), 15 % formic acid (based on dry biomass), 180 °C, and 60 min. The yield of the resulted crude lignin was 29.2 % with a purity of 54.6 %, and yield of crude cellulose was 64.6 % with a high purity of 84.3 %.

Preparation and Thermal Decomposition Kinetics of Novel Silane Coupling Agent with Mercapto Group

Using carbon disulfide and 3-aminopropyltriethoxysilane as raw materials, a novel silane coupling agent with a terminal group was synthesized for the first time. The compound was synthesized in two steps in ethanol water solvent under the action of the catalyst triethylamine and a sulfhydryl-protecting agent. The product was characterized by FT-IR, 1H NMR, and mass spectra to determine and prove its structure. The best experimental scheme was explored by a single factor experiment: a thiol-protecting agent selected iodomethane, the total reaction time was 2 hours, the two-step reaction temperature was 15°C and 10°C, respectively, and ncarbon disulfide: n3−aminopropyl three ethoxysilane=1.4:1. Under these conditions, the product yield was up to 74.28%. Secondly, using the nonisothermal decomposition method, the thermal stability and thermal decomposition enthalpy of a thiohydrazide-iminopropyltriethoxysilane coupling agent were measured by a differential scanning calorimeter (DSC). Thereby, the thermal decomposition kinetic parameters and kinetic equations of the thiohydrazide-iminopropyltriethoxysilane coupling agent were derived.