The article deals with materials science issues concerning the application areas in dental engineering. The monograph aims to present the results of the Author’s work against the background of general achievements, indicating the engineering aspects of dental implant-prosthetic treatment. They include clinical cases, most often concerning complete edentulism, with a detailed discussion of the methodology of the material, technological, and structural design of dental prosthetic restorations, especially the impact of additive manufacturing conditions and surface engineering technology on the mechanical properties and structure of prosthetic restorations.The monograph covering the engineering and technical activities of implant prosthetic treatment includes the Author's aspects concerning the development of the methodology of computer-aided design of dental prosthetic restorations and surgical guides ensuring their correct installation in the oral cavity of patients, along with virtual modelling of treatment plans, modelling of the load status of individual elements of implant-prosthetic systems, development of the methodology of computer-aided production of elements of the prosthetic restoration system as well as implants and implant-scaffolds with the use of milling technology in CNC centres and additive manufacturing by selective laser sintering, the results of research on the influence of additive manufacturing conditions on the structure and properties of titanium and its alloy Ti6Al4V and cobalt alloy Co25Cr5W5MoSi containing studies of biochemical properties for applications for implant-prosthetic purposes in dentistry, the results of tests on the influence of ALD atomic layer conditions on the structure and surface properties of metals and their alloys used in implant-prosthetic treatment in dentistry and the results of tests of prosthetic fillings used in the treatment of Tooth decay.The basis for all the described achievements of the monograph are the comprehensive results of research related to the study of the structure and properties of engineering materials, especially titanium and cobalt alloys used in dentistry, subjected to additive manufacturing using the Selective Laser Sintering SLS method and surface treatment using the Atomic Layer Deposition ALD method, as a domain of materials engineering, in the context of the Industry Integrated Idea 3xI 4 model. 0/5.0 and the 6xE 6 Expectation Principle, which there is a paradigm for materials science. What is important in the approach are the results of biological tests of materials produced in such a way, leading to numerous applications in the Author’s clinical practice in cooperation with dentists and the development of a general concept of a research, design, and production centre for prosthetic restorations and virtual acquisition of diagnostic data from cooperating dental clinics.The article is a monographic study referring to numerous of the Author’s publications, patents, and presentations at scientific conferences and invention fairs, in which very extensive source information is provided concerning both a very large number of literature items and extensive factual material, including the results of materiallographic studies and descriptions of clinical cases, although this study also presents numerous aspects not yet published in any previous works.The study presents, among others, detailed prosthetic and implant-prosthetic solutions implemented by the Author of the study and successfully used by patients. Although the study is formally qualified in the engineering and technical sciences in materials engineering, it has strong links with biomedical engineering and the applied area of interventional dentistry.Numerous original publications, patent solutions, completed projects, and awards at the International Innovation Fair discussed in the monograph, as well as clinical experience related to the treatment of thousands of dental patients in our Author’s clinic, confirm the originality of the approach and indicate the innovative nature of the achievements presented in the article so far. Many years of experience have led to the launch of a constantly developed production centre for prosthetic restorations and a virtual structure for obtaining diagnostic data from cooperating dental clinics. The article addresses scientists dealing with materials engineering applied in interventional dentistry and dental engineers in practice dealing with this issue.