Effects Of Energy Drinks Research Articles

Effect of Energy Drink on the Pancreas of Adult Male Albino Rat and the Possible Protective Role of Avocado Oil. Histological and Immunohistochemical Study

Introduction: Energy drinks are widely used among youth as boosters to increase their concentration. Many Health disorders associated with energy drinks have been reported. Avocado oil is a natural oil extracted from avocado fruit and possess an antioxidant and anti-inflammatory effects. Aim of the work: This work was conducted to investigate the effect of energy drink on the histological structure of the pancreas of adult male albino rat and to evaluate the possible protective role of avocado oil.Materials and Methods: Forty adult male albino rats were divided equally into 4 groups; control group, avocado oil-treated group (0.4 mg/100 gm body weight), energy drink-treated group (1.5 mg/100 gm body weight) and both avocado oil and energy drink treated group. All animals were orally administrated once daily for 4 weeks. Pancreatic specimens were processed for light and electron microscopy. Immunohistochemical study was performed using insulin and caspase-3 antibodies. Results: Energy drink-treated group revealed focal disturbed architecture of the exocrine and endocrine parts of pancreas. The exocrine pancreas appeared with cytoplasmic vacuolations and deeply stained nuclei of the acinar cells in addition to congested blood vessels. Ultrastructural examination revealed both acinar and islet cells with cytoplasmic vacuolations, swollen mitochondria with disrupted cristae, dilated rough endoplasmic reticulum in addition to shrunken condensed nuclei with dilated perinuclear cisternae. The immunohistochemical study showed a significant decrease in the insulin immunoreaction of β cells associated with a significant increase in caspase-3 immunoreaction in acinar and islet cells. In contrast, minimal changes were observed in rats treated concomitantly with avocado oil and energy drink with a non-significant change in the immunohistochemical reaction. Conclusion: Energy drink induced structural changes in the pancreas of rats and the concomitant intake of avocado oil could to some extent ameliorate such changes

Effect of Energy Drinks on Microsurgical Hand Tremor.

Effect of Energy Drinks on Microsurgical Hand Tremor.

Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytes

Consumption of energy drinks has been associated with adverse cardiovascular effects; however, little is known about the ingredients that may contribute to these effects. We therefore characterized the chemical profiles and in vitro effects of energy drinks and their ingredients on human induced pluripotent stem cell (iPSC)-derived cardiomyocytes, and identified the putative active ingredients using a multivariate prediction model. Energy drinks from 17 widely-available over-the-counter brands were evaluated in this study. The concentrations of six common ingredients (caffeine, taurine, riboflavin, pantothenic acid, adenine, and L-methionine) were quantified by coupling liquid chromatography with a triple quadrupole mass spectrometer for the acquisition of LC-MS/MS spectra. In addition, untargeted analyses for each beverage were performed with a platform combining LC, ion mobility spectrometry and mass spectrometry (LC-IMS-MS) measurements. Approximately 300 features were observed across samples in the untargeted studies, and of these ~100 were identified. In vitro effects of energy drinks and some of their ingredients were then tested in iPSC-derived cardiomyocytes. Data on the beat rate (positive and negative chronotropy), ion channel function (QT prolongation), and cytotoxicity were collected in a dilution series. We found that some of the energy drinks elicited adverse effects on the cardiomyocytes with the most common being an increase in the beat rate, while QT prolongation was also observed at the lowest concentrations. Finally, concentration addition modeling using quantitative data from the 6 common ingredients and multivariate prediction modeling was used to determine potential ingredients responsible for the adverse effects on the cardiomyocytes. These analyses suggested theophylline, adenine, and azelate as possibly contributing to the in vitro effects of energy drinks on QT prolongation in cardiomyocytes.

Effect of Energy Drinks on Color Stability of Different Restorative Materials

Background: The purpose of this in vitro study was to evaluate the effect of finishing/polishing procedures on color stability of three restorative materials: Nano-hybrid resin composite (NRC), silver glass ionomer cement (SGI), and resin-modified glass ionomer cement (RMGI) exposed to different staining of energy drinks: Barbican, Bison, and Red bull.

Effects of Energy Drink on Glomerular Parameters and its Conservation by Vitamin D3

Objective: Use of energy drinks is increasing now a days and red bull is common brand used by youth that causes nephrotoxicity. Therefore present study was conducted to observe conservative effect of vitamin D3 on renal histomorphological changes induced by EDs. Study design: Laboratory based experimental study. Place and duration of study: The research was carried out from 1st august to 30th September 2019 at National institute of health (NIH), Islamabad. Material and Method: Total thirty adult male albino rats were divided into 3 groups, each group containing ten rats. Group A was control group while rats in group B received 3.57ml/kg body weight red bull that corresponds to one can of ED (250ml) in humans orally for 8 weeks. Rats in group C received 3.57ml/kg body weight red bull along with 5000 IU/kg body weight vitamin D3 orally for 8 weeks. After completion of 8 weeks rats were sacrificed their right kidneys were removed and Slides were prepared using PAS stain. Readings were taken through image j software and results were analyzed by SPSS. Results: The results demonstrated that in group B use of red bull for 8 weeks resulted in decrease in radius and diameter of glomerular along with widening of bowman capsule space. In group C radius of glomerulus, diameter of glomerulus and bowman capsule space was near to control group. This showed that vitamin D3 conserved glomerulus histology significantly in group C and prevented renal damage (P≤0.05). Conclusion: In conclusion, vitamin D3 is having noticeable conservative effect in preventing renal histomorphological changes caused energy drink.

Sociodemographic differences, prevalence, and patterns of energy drink consumption among Jazan university students, Saudi Arabia

Energy drinks are beverages containing a high amount of caffeine and other substances. Studies on the side effects of energy drink consumption among college students in Saudi Arabia are limited. In this cross-sectional study, we aimed to determine the consumption patterns and effects of energy drinks among college students. The study was conducted using a self-administered questionnaire about sociodemographic differences, prevalence, and patterns of energy drink consumption. A total of 458 stude

Procena efekata energetskih napitaka na kardiovaskularni sistem kod studenata medicinskih nauka

Introduction: Energy potion is non-alcoholic drink, which is mostly used by young people to achieve wanted effects. But, these drinks can cause unwanted effects as well, such as cardiovascular disorder, CNS disorder and gastro-interstinal system disorder. The aim of the study was to assess the frequency of consumption of energy drinks and the knowledge of medical students regarding possible side effects, as well as to determine the acute effects after consuming energy drinks on arterial blood pressure, hemoglobin oxygen saturation, pulse and respiration. Material and methods: This study was conducted as an analytical, observational cross-sectional study at the Faculty of Medicine in Novi Sad. The Questionnaire on the level of knowledge and experience about the desired and unwanted effects of energy drinks was used as a research instrument. Results: Students consume energy drinks (80%) and have knowledge of possible side effects (88%). After consuming the energy drink, the differences between the average values of systolic and diastolic blood pressure, hemoglobin oxygen saturation and respiration rate were determined. Conclusion: The results of the study show that most students, although they have knowledge about side effects, still consume energy drinks. Changes in cardiorespiratory function after consuming an energy drink were most pronounced in the values of arterial blood pressure.

Investigation into the Negative Effects of Energy Drinks on Liver Efficiency and Lipid Metabolism in Rats

Investigation into the Negative Effects of Energy Drinks on Liver Efficiency and Lipid Metabolism in Rats

Adverse Effects of Energy Drinks, a Challenge for Medicine: A Case Report.

In Mexico, an estimate of the monthly average consumption of these drinks was 36,240,000 liters [1]. The use of these products is to increase energy levels during physical activity or exam periods to avoid sleep. Despite the increase in its use, there is ignorance in its consumers about its level of safety in its consumption [2]. Energy drinks (ED) appeared on the market as a mixture of carbohydrates, vitamins, and caffeine. Later, alcohol blends were made for cocktails, so their popularity increased. The high consumption of ED is due to the mental stimulating effect by the high levels of caffeine, taurine and glucuronolactone [3].

Energy Drink Effects on Hemodynamics and Endothelial Function in Young Adults

Introduction: Cardiovascular side effects associated with energy drink consumption may be related to effects on vascular endothelial function, heart rate, blood pressure, and electrocardiogram parameters. We sought to measure them following energy drink consumption. Methods: Forty-four healthy non-smoking young volunteer medical students, at an average age of 24.7 years (range 23–27 years, 34 males), with an average BMI of 23.4, received electrocardiograms and had their heart rates and blood pressures taken. Subjects then underwent baseline testing of endothelial function using the technique of endothelium-dependent flow-mediated dilatation (FMD) with high-resolution ultrasound. The subjects then drank an energy drink (24 oz Monster Energy Drink®). Hemodynamic measurements were repeated 15 and 90 min later. FMD and the electrocardiogram were repeated 90 min later. The FMD was calculated as the ratio of the post-cuff release and the baseline diameter. Results: Energy drink consumption resulted in a significantly attenuated peak FMD response (mean ± SD): baseline 5.1 ± 4.1% versus post-energy drink (2.8 ± 3.8%; p = 0.004). In addition, systolic and diastolic blood pressures and heart rate increased after 15 min. Diastolic blood pressure and heart rate remained increased 90 min following energy drink consumption. There were no significant changes in electrocardiogram parameters. Conclusion: Energy drink consumption was associated with an acute significant impairment in endothelial function in young healthy adults as well as with significant hemodynamic changes. As energy drinks are becoming more popular, it is important to study their effects to better determine safe consumption patterns.

Morphometric Study on the Energy Drink Induced Pancreatitis on Wistar Albino Rats

Objective: To assess the effects of energy drinks on the micrometric measurements of pancreas of Wistar Albino rats. Methods: This experimental study was conducted in the Department of Anatomy, in collaboration with the animal house of Basic Medical Sciences Institute (BMSI), Jinnah postgraduate medical center (JPMC), Karachi from September to October 2018. Thirty adult male Wistar Albino rats were equally divided into three groups (Group A as control, while groups B and C were administered 7.5ml and 15ml orally for four weeks, respectively. Pancreas was dissected out at the end of study. After tissue processing, slides were made and stained with hematoxylin and eosin stain (H&E) to observe the morphology and cytoarchitecture of the tissue. Results: The findings of the study revealed that the mean diameter of pancreatic acini and islets were significantly lower in Group B (12.70 +- 1.20), (63.52 +- 8.98) as compared to Group A (26.29 +- 4.37), (123.66 +- 22.08) respectively, p-value <0.05. Diameter of pancreatic acini and islets were significantly less in Group C (10.06 +- 0.89), (44.58 +- 7.66) as compared to both Groups A (26.29 +- 4.37), (123.66 +- 22.08) and Group B (12.70 +- 1.20), (63.52 +- 8.98) respectively, p-value <0.01. The parenchyma of the observed organ was also damaged with loss of normal cytoarchitecture as observed on microscopy. Conclusion: The results obtained in the current study suggest that consumption of energy drinks seriously damages the regular anatomy of the pancreas of Wistar Albino rats.

Energy-drink consumption is associated with asthma, allergic rhinitis, and atopic dermatitis in Korean adolescents

Few studies have evaluated the effects of energy drinks on allergic diseases. The purpose of this investigation was to evaluate the association between energy drinks and various allergic diseases, including asthma, allergic rhinitis, and atopic dermatitis, in a large representative Korean adolescent population. This cross-sectional study used data from the Korea Youth Risk Behavior Web-based Survey collected from 2015 to 2016. A total of 129,809 participants (n = 67,056 for males; n = 62,753 for females) aged 12-18 years were included and were asked about their frequency of consumption of energy drinks such as Hot6®, Redbull®, and Bacchus®. Their history of asthma, allergic rhinitis, and atopic dermatitis throughout life and in the last 12 months were obtained. The association between the frequency of energy-drink consumption and allergic diseases was analyzed using multiple logistic regression with adjustment for various covariates. Age, sex, physical activity, obesity, region of residence, economic level, paternal and maternal educational level, smoking, and alcohol consumption differed significantly according to the frequency of energy-drink consumption (each P < 0.001). Frequent energy-drink consumption (≥7 times a week) was significantly associated with asthma throughout life (odds ratio [OR] = 1.30, 95% confidence interval (CI) = 1.03-1.64, P = 0.025), asthma within the last 12 months (OR = 1.65, 95% CI = 1.16-2.35, P = 0.006), allergic rhinitis within the last 12 months (OR = 1.21, 95% CI = 1.02-1.44, P = 0.030), and atopic dermatitis within the last 12 months (OR = 1.49, 95% CI = 1.17-1.90, P = 0.001) compared to no energy-drink consumption in the full-adjusted model. Frequent energy-drink consumption is associated with allergic diseases, including asthma, allergic rhinitis, and atopic dermatitis, in Korean adolescents.

Effect of caffeinated energy drinks on the structure of hippocampal cornu ammonis 1 and dentate gyrus of adult male albino rats.

Energy drinks are available worldwide and frequently consumed to increase energy level and compensate lack of sleep. Energy drinks consumers aim to improve their cognitive functions. Red Bull is the most popular energy drink consumed in Egypt. However, the link between the impact of energy drinks on the structure of hippocampal cornu ammonis 1 (CA1) and dentate gyrus (DG), a highly vulnerable brain regions to various insults, has not yet documented. To study the effect of energy drinks on structure of hippocampal CA1 and DG of adult male albino rats. Twenty one adult male albino rats were divided into three groups; group I control group, groups II and III received Red Bull, with a dose of 3.75 ml/kg/day orally using gastric tube for four and eight consecutive weeks respectively. At the end of the experiment, brains were dissected and hippocampal specimens were processed for histopathological and immunohistochemical studies. Histopathological examination of hippocampal sections in group II revealed vacuoles, decrease thickness of pyramidal cell layer with irregular dark or ghost nuclei. However, changes were more severe in group III with cracks in pyramidal cell layer, massive vacuolation and signet ring cells. Moreover, star shaped astrocytes and glial fibrillary acidic protein immuno-reactivity were more abundant in group III than in group II. Caffeinated energy drinks produced neurodegenerative changes and reactive astrocytosis in hippocampal CA1 and DG of adult male albino rats. These changes were duration-dependent being more severe in longer duration of intake.

Effects of Energy Drink in Combination with Two Different Brands of Alcohol on Some Biochemical Parameters of Male Albino Rats

This study was carried out to ascertain the effect of energy drink and mixture of energy drink with different brands of alcohol on some biochemical parameters. Sixteen (16) male albino rats weighing 120- 160g were divided into four (4) groups. The groups were divided thus: Group 1: Control- feed and water ad libitum, Group 2: 3.75ml/kg Bullet Energy drink only, Group 3: 3.75ml/kg Bullet energy drink + 1ml/kg of 41% alcohol dry gin and Group 4: 3.75ml/kg Bullet energy drink + 1ml/kg of 5.1% alcoholic beer. The experiment lasted for 28 days after which the animals were fasted for 12 hours before they were sacrificed and their blood collected for biochemical analyses. There was a significant increase in body weight of animals in group 2-4 and also the glucose concentration was elevated. The result presented in table 2 showed that there is a statistically significant difference (p&lt;0.05) in the level of ALT and ALP in treatment groups when compared to the control group (1). Also, elevated level of cholesterol and triglycerides were also observed. From this data, we may conclude that there are high risk of constantly taking energy drink alone or in combination with alcohol.

Energy drink: the consumption prevalence, and awareness of its potential health implications among commercial drivers in the Ho municipality of Ghana

BackgroundConsumption of energy drinks has become an escalating global public health problem. The work schedule and irregular sleeping habits of commercial bus drivers make them highly susceptible to getting fatigued, hence most of them consume energy drinks as a fatigue management strategy. However, consumption of energy drinks produces numerous psychomotor side effects that if consumed among drivers puts the traveling public in danger of road accidents. This study sought to assess the prevalence of energy drink consumption and awareness of associated potential health problems among commercial long-distance bus drivers operating from the Ho municipality.MethodsThe study population comprised about 266 commercial bus drivers. This was a cross-sectional study involving 132 participants who completed a structured questionnaire on the participants’ socio-demographic characteristics, frequency of consumption and reasons for consumption. It also included questions to assess the knowledge of the ingredients and side effects of energy drinks. Respondents were selected using a convenience sampling technique. Descriptive analysis and Chi-square test of association were used to analyse the data.ResultsA majority (62.1%) of the drivers had more than 10 years of commercial driving experience. A 75% energy drink consumption prevalence was recorded with driving performance enhancement (78.8%) as the predominant reason for consumption. 7–10 bottles per week were consumed by most (32.2%) of the drivers. Also, 72.0% had poor knowledge of the side effects linked with energy drink consumption as well as the ingredients for preparation.ConclusionEnergy drinks were consumed by the majority of the drivers at the Ho main bus terminal of which most of the drivers had poor knowledge of the potential health problems linked with the consumption of these drinks. The consumption of energy drinks was observed to be higher among the drivers with lower education levels, higher monthly income and those who worked long hours in a day. The Ghana National Road Safety Commission (GNRC) in collaboration with other private road transport unions in Ghana should organize regular seminars for commercial bus drivers on the potential dangers and effects associated with energy drink consumption.

Surface degradation evaluation of different self-adhesive restorative materials after prolonged energy drinks exposure.

To evaluate the effects of energy drinks and soft beverages on the surface degradation of different self-adhesive materials. A 156 disc shaped specimens of each of the following materials were prepared: Alkasite (Cention N, CN), High viscozity glass ionomer (Equia Forte, EF), Glass Carbomer (GCP Fill, GC) (n = 52). After specimen preparations, baseline surface roughness measurements were done using a 3D non-contact optical profilometer. Then, specimens were subdivided into 4 subgroups (n = 13) and stored in petri dish containing Red Bull; Burn; Coca-Cola and Distilled water. The surface roughness of the specimens were measured after 1-day, 1-week, and 1-month of immersion in beverages. It was observed that 1-month Red Bull immersion revealed the highest roughness difference (ΔRa) for each self-adhesive restorative material and this was followed by Burn. Whereas, the lowest ΔRa values were observed after 1-day coke and distilled water immersion in all tested material groups (P < 0.05). Coke and distilled water presented the energy drinks' 1-day immersion affect, after 1-week immersion (P < 0.05). The energy drinks have a substantially damaging effect on roughness of self adhesive materials compared with soft drinks and distilled water; and this effect is increasing with exposure duration.

Effect of Energy Drinks on the Inorganic Composition of a Composite Resin Material

Composite resins are used in Dentistry to perform direct aesthetic restorations, and are a material whose properties can be influenced by the diet of the individual, especially in the face of the action of beverages with acid pH, such as energy drinks. The aim of this in vitro study was to evaluate the effect of two energy beverages on the chemical composition of a nanoparticulate composite resin, at two-time intervals. Filtek Z350XT (3M/ESPE) composite resin was used to produce thirty-six specimens (discs) of 6.0mm x 1.5mm dimensions. The specimens were initially immersed in distilled water for 24h at 37ºC and then randomly divided into two groups (n=18); according to the immersion time: 1 month (T1) and 3 months (T2); and in three subgroups (n=6) referring to immersion solutions: distilled water (control) and two energy beverages (RedBull and Monster). The inorganic composition of the specimens was measured by a spectrometry. The data were submitted to two-way ANOVA and Tukey tests. The main inorganic elements of this restorative material were respectively: zirconium (Zr), silicon (Si) and calcium (Ca), which reduced its percentage after immersion time. RedBull was the most active solution, promoting losses of the mineral Si after 1 month of immersion, of Zr, after 3 months, and of Ca after 1 month and after 3 months. Monster influenced losses only in Si, after 1 month. Distilled water did not induce significant losses. Thus, the two energy beverages reduced the inorganic percentage of the nanoparticulate composite resin evaluated in this research.

Cardiovascular Effects of Energy Drinks in the Pediatric Population.

Consumption of energy drinks in the pediatric population is correlated with more emergency department visits and causes adverse reactions, such as neurological, psychiatric, gastrointestinal, renal, and cardiovascular effects. These cardiovascular complications include increased cardiometabolic risk with high intake of sugar, short-term blood pressure increases and a decrease in cerebral blood flow due to the caffeine content, increased or decreased blood pressure from taurine, unmasked cardiac conditions, such as channelopathies, and atrial and ventral fibrillations. Cardiovascular complications can also arise when energy drinks are mixed with pharmaceutical drugs, such as amiodarone, potent CYP1A2 inhibitors, warfarin, digoxin, or corticosteroids. Combining energy drinks with alcohol also precipitates adverse cardiovascular events, posing a risk to the health of children and adolescents. This review further explores the ingredients in energy drinks and their mechanism of action in causing these cardiovascular complications.

Adverse effects of energy drink on rat pancreas and the therapeutic role of each of bone marrow mesenchymal stem cells and Nigella Sativa oil.

Energy drinks have been observed to threaten public health leading to many medical problems. Bone marrow-derived mesenchymal stem cells (BMSCs) have broad prospects in tissue regeneration. Nigella Sativa (NS) possess great therapeutic properties for the treatment of a wide range of diseases. Forty adult male albino rats were divided into: control group and treated group. The treated group was further subdivided into: energy drink subgroup 2a, BMSCs-injected subgroup 2b, NS-injected subgroup 2c. Histological, immunohistochemical and biochemical assessment was performed. Administration of energy drink revealed that it adversely affected the pancreatic cytoarchitecture. BMSCs and NS have been similarly observed to significantly ameliorate the histological, biochemical and immunohistochemical changes induced by energy drink. The extent of pancreatic regeneration, exerted by each of BMSCs and NS oil, is nearly similar but the effect of BMSCs is more superior; however, NS could be privileged to BMSCs as a line of treatment being easily accessible and of lower cost.

Hepatic &amp; Renal Toxicity of Energy Drinks, a Serious Health Risk, Wistar Albino Rats Study

The recent years have seen a significant increase in the individual consumption of energy drinks across the globe. As a result, notable concerns continue to rise both among the public and among the scientific community, concerning the health effects that energy drinks pose to individuals. This study therefore examines the adverse effects of energy drinks on health, using ten normal albino rats as specimens. The specimen was then divided into two groups consisting of five rats each, with one group was given energy drinks while the control group was given normal drinking water days for a period of 21 days. The specimen was then sacrificed and their blood samples used for biochemical and histological studies. The study findings reveal that energy drink consumption significantly increased the serum aspartate amino transferase (AST), alanine amino transferase (ALT), urea and creatinine levels when compared with the control group. In addition, the study demonstrates that energy drink consumption significantly decreased body weight and organ to body weight ratios when compared with the control group. The study further recognizes that the consumption of energy drink is associated with significant alterations in serum toxicity markers, bodyweight, organ body weight and histopathological changes. The study therefore recommends that need for public health education to educate individuals; especially youths about the risks of consuming highly caffeinated energy drinks. The study also recommends the need for further studies in order to minimize the harm excess and long-term consumption of energy drinks presented to the public.