A novel concept for the americium-containing target, which consists of (Th,Am)O2-x and molybdenum support material, is proposed that can fulfill several requirements such as reduction of the environmental burden and effective use of natural resources. In particular, deployment of recovered molybdenum from the spent nuclear fuel is highlighted and its nuclear effects are focused on in comparison to other types of molybdenum, namely natural and enriched ones. A preliminary investigation for effects of molybdenum isotopic composition on fast reactor core characteristics were carried out using nuclear calculation codes. The results indicated the feasibility of the fast reactor core loaded with the present target by optimizing its amount and composition. Moreover, several additional gains were indicated such as possible use of the radioactive waste and production of a new energy source, 233U.