The necessity of developing a system of regulators to ensure the sustainability of reproductive processes in industrial fruit growing is substantiated. An assessment of the efficiency of fruit production in the Russian Federation is given. The factors influencing the decrease in the stability of reproductive processes in industrial fruit growing are identified: an increase in the cost of purchased resources; high cost of finished products; a reduction in the share of subsidies in the created cost of planting; the insufficiency of agricultural producers’ own financial resources for carrying out planned plantings renovations, updating production infrastructure funds and carrying out current production activities. Functional imbalances in the organization of reproductive processes in industrial fruit growing have been identified: internal structural imbalances, high resource intensity of production and technological processes, non-compliance with optimal comparability of production and economic indicators. Generalizing criteria for the sustainability of reproductive processes are systematized: the ability of the system to withstand negative impacts of an economic and natural nature; increasing the possibilities of expanded reproduction of all used resources; ensuring qualitative changes in the production, socio-economic, environmental parameters of the system; increasing the conditions for subsequent improvements, preventing production declines. The article characterizes and evaluates the effectiveness of existing regulators to ensure the sustainability of reproductive processes in industrial fruit growing (macroeconomic, technical, technological and economic). A system of regulators has been developed to ensure the stability of reproductive processes in industrial fruit growing in functional areas of influence. An algorithm is proposed to substantiate the necessary dimensionality of regulators to ensure the stability of reproductive processes in industrial fruit growing.