: In this article, the Caputo Fabrizio fractal fractional order derivatives operator with an exponential kernel was employed to examine the radiative heat and mass transfer characteristics of time dependent flow with variable fluid viscosity, induced magnetic field, Soret and Dufour effects. The local mathematical model for the flow problem is formulated by take into account the impacts of thermal radiation, heat source, and viscous dissipation. The governing equations in-terms of fractal fractional model with an exponential kernel were solved numerically using finite difference method. The influence of flow variables such as induced magnetic field, concentration field, entropy rate, thermal field, and velocity field profiles against the pertinent parameters are discussed through graphs. Increase the values of magnetic Prandtl number results to rises of induced magnetic field. Higher Dufour number significantly grows the thermal field. The fractal fractional parameters enhance the velocity field, thermal field, Bejan number, entropy rate, concentration field and induced magnetic field profiles. The velocity field profiles recede with higher values of fluid variable viscosity parameter whereas the thermal field and induced magnetic field has an opposite effect. Larger Soret number amplifies the concentration field. Increase of Brinkman number, thermal radiation parameter, and magnetic Prandtl number intensifies the entropy generation rate. Increases of Brinkman number, magnetic Prandtl number, Soret number and Dufour number leads to a decrease of Bejan number whereas Bejan number rises with an increase of thermal radiation parameter and heat source