This paper concerns an analysis of the accuracy of the estimated parameters Ω (Φ, Λ, ω) which define the tectonic plate motions. The study is based on the velocities of station positions in the IERS (International Earth Rotation and Reference Systems Service) which has published new realization of the International Terrestrial Reference System—ITRF2008 for Doppler Orbitography by Radiopositioning Integrated on Satellite DORIS technique. Eurasian, African, Australian, North American, Australian, Pacific, Antarctic and South American plates were used in the analysis. The influence of the number and localization of stations on the plate surface on the estimation accuracy of the tectonic plate motion parameters were discussed. The results were compared with the APKIM 2005 IGN model and our earlier estimation for the SLR technique. In general, a remarkable concurrent agreement between the present and the APKIM 2005 solutions was found.