Distribution Of ABO Blood Groups Research Articles

Distribution of ABO and Rh-D Blood Group Antigens Among Blood Donors in the Amhara Regional State, Ethiopia.

BackgroundThe ABO and Rh blood group systems are the most commonly used blood group systems in clinical settings. They are clinically significant for blood transfusion, organ transplantation, genetic studies, forensic determinations, and medico-legal issues. Therefore, this study aimed to determine the distribution of ABO and Rh-D blood groups among blood donors in the Amhara regional state, Ethiopia.MethodsA cross-sectional study was conducted from March 2016 to September 2018 among blood donors in the four blood bank districts (Gondar, Bahir Dar, Debre Markos, and Dessie) of the Amhara regional state, Ethiopia. A total of 1040 blood donors aged from 18 years old to 60 years old were included using a simple random sampling technique. A structured questionnaire and a data collection sheet were used to obtain the socio-demographic data and blood group types of study participants. The ABO and Rh-D blood groups were typed using commercially prepared antisera after 1 mL of blood was taken from blood bags. The data was cleared by Epi-Info Version 7 and extracted into SPSS version 25 for analysis. The distribution of data was checked by using the Shapiro–Wilk test. Then, the data was presented in tables and figures.ResultsIn this study, out of 1040 study participants, 55.6% were males with a median age of 20 years (IQR = 19–24 years). In this study, the distribution of ABO blood types O, A, B, and AB was 41.6% (433/1040), 28.7% (298/1040), 22.2% (229/1040), and 7.7% (80/1040), respectively. On the other hand, the Rh-D positivity was 92.5% (962/1040).ConclusionThe overall predominant ABO blood group in the Amhara regional state was O (41.6%), and the least was AB (7.7%). Besides, the overall Rh-D negative blood distribution was 7.5%, which ranged from 4.46% to 9.6%. Therefore, this information would be useful to the blood banks, especially in the planning of blood transfusion programmers.

Blood Group Distribution Characteristics of COVID-19 Patients in Xinjiang

To analyze and summarize ABO and Rh(D) blood group distribution and related indicators of COVID-19 patients, and understand the relationship between blood group and disease course of COVID-19 patients in Xinjiang. A total of 831 patients with confirmed or asymptomatic COVID-19 infection treated in People's Hospital of Xinjiang Uygur Autonomous Region from July 2020 to August 2020 were enrolled as study group, and 2 778 healthy people in a third Grade A hospital in the region during the same period were selected as control group. ABO and Rh(D) blood group antigens were identified, and relevant medical data were collected for statistical analysis. The proportion of O-type population and Rh(D) positive population in the study group was 24.79% and 96.27%, which were lower than those in the normal control group (29.73% and 97.73%) (P<0.05). The proportion of AB type and Rh(D) negative population was 14.20% and 3.73%, which was higher than that in control group (10.62% and 2.27%) (P<0.05). The proportion of female patients in Type O group was lower than that in control group. The proportion of female patients in AB group was higher than that in control group (P<0.01), while the proportion of type O patients in the age group less than or equal to 45 years old and greater than 60 years old was lower. Different blood groups of Uygur population showed their own characteristics in different sex, but there was no statistical significance due to the limited sample (P>0.05). Moreover, the course of disease and clinical diagnosis of COVID-19 patients were different among different blood groups (P<0.05). This study found that the blood type distribution of COVID-19 patients in Xinjiang has its own characteristics, and the blood type is related to the course and clinical diagnosis of COVID-19. In the future, the data can be widely included in people from different ethnic groups and different regions to improve relevant studies.

Distribution and Frequency of ABO and Rhesus (D) Blood Groups in Somalia: A Retrospective Study on Students of Jazeera University, Mogadishu-Somalia.

Background There are differences in the distribution and frequency of ABO and D blood groups in different populations of the world. Relatively very little information is available about blood group distributions in the Somali population. Objectives: To identify the distribution and frequency of ABO and D blood groups among the Somali people. Methods A retrospective cross-sectional study of 1811 enrolled students of Jazeera University was conducted in Jazeera University diagnosis and research center, Mogadishu-Somalia from December 2017 to December 2020. The result was presented as the frequency of each blood group with percentage. A Fisher's exact test was carried out to test the significant association of the ABO blood group with sex and D antigen with sex. Results Blood group O was the most prevalent (61%), followed by A (27%), B (10%), and AB (2%). The D-antigen was present in 97% of participants and 3% were D-negative. The distribution of O+, A+, B+, AB+ among D-positive subjects were 62%, 27%, 9% and 2.0% while that of O-, A-, B- and AB- among D-negative subjects were 57%, 27%, 12% and 3%, respectively. The frequencies of ABO and D-antigens in both male and female subjects were O > A > B > AB. However, this study found no significant difference of ABO with Sex and D-antigens with sex (P-value>0.05). Conclusions The frequency of ABO and D blood groups among the Somalia population was found to be O > A > B > AB which was similar to those reported from most East African populations.

ABO blood group and Rh factor distributions in patients with epilepsy

ObjectiveWe investigated the ABO blood group and Rh factor distributions in patients with epilepsy (PWE) in comparison with a comparator population. MethodsWe recruited patients who were admitted to the epilepsy ward at Namazi hospital in Shiraz, Iran, in 2021. We classified epilepsies into two categories: focal vs. generalized. We also used the anonymous data from Fars Blood Transfusion Organization from 15th June to 30th June, 2021, as the comparator population (to estimate the frequencies of various blood types in the cohort from which PWE were recruited). ResultsOverall, 390 PWE were included [131 (33.6%) with generalized and 259 (66.4%) with focal epilepsy]. We also included 7672 blood donors [from Fars Blood Transfusion Organization data]. The O phenotype had the highest frequencies in both PWE and the comparator population, followed by A, B, and AB blood groups. Similar patterns were observed in patients with focal and generalized epilepsy. With regard to Rh blood group, the Rh-positive phenotype was more prevalent in all groups. The differences between the groups were not significant in any of the comparisons. ConclusionWhile we did not observe any significant associations between blood group and epilepsy in the current study, previous studies have demonstrated compelling evidence that risks of some neuropsychiatric disorders are related to the chemistry of blood, including blood group classification. The issue of the association between epilepsy and blood group should be investigated in large and well-designed studies in the future.

ABO blood group in aneurysmal subarachnoid haemorrhage—a pilot study

To evaluate the distribution and impact of ABO blood group on the baseline characteristics and clinical outcomes of patients presenting with aneurysmal subarachnoid haemorrhage (aSAH). Retrospective, single-centre study of patients admitted to a neurosurgical department in the UK, with a diagnosis of spontaneous subarachnoid haemorrhage between May 2014 and January 2020. Patients were categorised by ABO blood type and by Rhesus status. Clinical outcomes such as initial bleeding, rebleeding, delayed cerebral ischaemia (DIND) and venous thromboembolism were analysed in relation to the size of their association with ABO blood type. Hospital mortality rate, Glasgow Outcome Score (GOS) - at discharge and 3months post-ictus, requirement for ventriculoperitoneal shunt insertion, discharge destination and inpatient length of stay were also considered. Four-hundred twelve adult patients admitted with aSAH were included in our analysis. The distribution of ABO group or Rhesus status in our cohort did not differ significantly from the general population in the UK. Blood group A patients had a significantly increased risk of developing DIND, compared with non-blood group A patients (OR, 1.88 [95% CI: 1.10-3.21]). ABO blood type appears to influence aSAH sequelae. Blood group A patients are at highest risk of DIND following aSAH.

DISTRIBUTION OF ABO BLOOD GROUP AMONG SOCIO-ECONOMICALLY BACKWARD COMMUNITY OF BIRAUL BLOCK OF DARBHANGA DISTRICT, BIHAR, INDIA

The demand for blood and blood products has increased due to advances in medical science, Population growth and increased life expectancy. Due to this the aim of present study to determine the ABO blood group system of various community of Biraul block. Blood samples were collected by door to door survey. The frequencies of ABO blood group distribution indicated blood group B was predominant in three Castes i.e. Dusadh, Chamar and Pasi followed by O, A and AB respectively. While in Brahman and Mallah, blood group O was predominant followed B,A and AB respectively. This study helps us to know the exact distribution of blood group in various castes of Biraul block of Darbhanga.

Association of ABO Blood Group Status in Patients with Breast Lesions and Emphasis on Invasive Breast Carcinoma

Introduction: The ABO blood group antigens are expressed on the erythrocyte membrane and on the surface of other normal and pathological cells. Recently, there has been an increasing research interest in the association between ABO blood group antigens and certain type of human cancers. Aim: To determine the association of ABO blood group and Rh blood type in patients with breast lesions. Materials and Methods: It was a retrospective observational study done at a rural tertiary care referral institute, PES Institute of Medical Sciences and Research (PESIMSR), Kuppam, Andhra Pradesh, India, from January 2015 to December 2018. Apparently healthy female voluntary blood donors constituted the control group (n=222). Patients with breast lesions constituted the study group (n=125). The association of the breast lesions with ABO blood group and Rh blood type was analysed. Frequencies, Chi‑square test and crosstabs were the statistical tools used for data analysis. All the statistical calculations were performed through Statistical Software for Data Science (STATA) version 14.1. Results: Total 125 cases of breast lesions were analysed. Neoplastic lesions 113 (90.4%) were more common than the non neoplastic lesions 12 (9.6%). Blood group “O” was the most common blood group in malignant neoplasms and was statistically significant (p=0.045). Blood group B was the most common blood group in grade II invasive breast carcinoma and was statistically just significant (p=0.05). Conclusion: A definite change in the pattern of distribution of ABO blood group was observed in grade II malignant neoplasms. It may be hypothesised that knowing the blood group of breast cancer patients may be beneficial in order to triage the patients for the purpose of efficient management.

Frequency and distribution of ABO and Rhesus (D) blood groups: A tertiary care hospital experience

Frequency and distribution of ABO and Rhesus (D) blood groups: A tertiary care hospital experience

The effect of ABO blood group on COVID-19 in pregnancy

Background: The COVID-19 virus has spread throughout the world and has been declared as a global pandemic by WHO. Some population groups are more susceptible to COVID-19, and one of them is pregnant women. Pregnancy increases risks of the COVID-19, especially thrombotic complications. The SARS-CoV-2 infection may vary widely from asymptomatic to severe infection. Some studies have shown that ABO blood group can be a marker of susceptibility to some disease progression. Objective:This study aims to investigate relationships between the ABO blood group, the COVID-19 infection and its complications in pregnant women at Dr. Moewardi Hospital, Surakarta.Methods: This study was an observational analytic study with a cross-sectional study design involving 40 pregnant women infected with COVID-19 at Dr. Moewardi Hospital, Surakarta. COVID-19 PCR swabs on the women were administered on their oropharynx and nasopharynx, and laboratory examination of the ABO blood group in all samples was performed. Comparative data distribution of blood groups in the population and the global population distribution were calculated by Chi Square Goodness of Fit. Comparative data between ABO blood group distributions, blood parameters and complications (respiratory, thrombotic, other infections, and death) were calculated by Chi square test and then by One-Way ANOVA. Next, correlation tests for the complications of the blood group and the ages applied a multinomial regression.Results: There were significant differences of thrombotic complications on the blood group of pregnant women infected with COVID-19 (p=0.027). Blood type B significantly tended to experience thrombotic complications when compared to other blood groups (p=0.022).Conclusion: The ABO blood group could affect the complication levels in the pregnant women infected with the COVID 19.

ABO blood group distribution and risk of malignancy in patients undergoing resection for intraductal papillary mucinous neoplasm (IPMN)

BackgroundThe ABO blood type has been associated with risk of development of several malignancies, including pancreatic cancer. Data regarding IPMN is equivocal. To investigate this further, we analyzed the association between the ABO blood group and the presence of malignancy in a large cohort of resected IPMN and its influence in survival. Methods819 patients who underwent pancreatic resection for IPMN in the Massachusetts General Hospital (MGH) and Cambridge University Hospitals NHS Foundation Trust (CUH) from January 1993 to December 2020 were identified from prospective institutional databases. Pathological characteristics and blood type were correlated. ResultsThe distribution of blood types A, B, AB and O was 384 (47%), 92 (11%), 44 (5%) and 299 (37%), respectively. This blood type distribution was different than the reference population of the MGH and the CUH, which is 55% non-O blood group, and 45% type O. There was a significant predominance of non-O blood types when compared with O-blood type in patients with malignant IPMN (i.e. patients with high-grade dysplasia and invasive cancer) (67% vs 33%, OR 1.31 95%CI: 0.98–1.75, p = 0.069). The association was stronger for IPMN with invasive cancer (OR 1.43 95%CI: 1.01–2.02, p = 0.039). Blood group did not influence survival. ConclusionNon-O blood type is associated with need for resection in IPMN and with presence of invasive carcinoma.

ABO and Rhesus Blood Groups in Acute Puumala Hantavirus Infection.

Puumala hantavirus (PUUV) causes hemorrhagic fever with renal syndrome. We aimed to evaluate whether ABO and rhesus blood groups associate with the susceptibility or the severity of PUUV infection. We analyzed blood groups in 289 adult patients treated in Tampere University hospital due to PUUV infection during the years 1982–2017. Patients’ blood group distribution was compared to that of healthy, voluntary blood donors living in the Tampere University Hospital responsibility area (n = 21,833). The severity of PUUV infection, as judged by the severity of acute kidney injury (AKI), thrombocytopenia, inflammation, capillary leakage, and the length of hospital care, was analyzed across the groups. The ABO and rhesus blood group distributions did not differ between the patients and blood donors. Patients with non-O blood groups had lower systolic blood pressure compared to patients with blood group O, but there was no difference in other markers of capillary leakage or in the severity of AKI. Minor deviations in the number of platelets and leukocytes were detected between the O and non-O blood groups. To conclude, patients with blood group O may be less susceptible to hypotension, but otherwise blood groups have no major influences on disease susceptibility or severity during acute PUUV infection.

ABO blood groups and risk of human immunodeficiency virus infection: A systematic review and meta-analysis.

The last few decades have seen a pandemic of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), which continues to cause substantial morbidity and mortality. ABO blood groups are anthropological and genetic characteristics of a population whose associations with HIV infection are still controversial. This systematic review with meta-analysis was undertaken to investigate whether certain blood groups may have associations with HIV infection. PubMed, Scopus and Web of Science databases were systematically searched as of 6 September 2021. Grey literature was identified through screening Google Scholar, and reference lists of relevant studies. All observational studies providing data on ABO blood group distribution among HIV-infected and uninfected participants were included. Using a random effect model, risk ratios (RR) and 95% confidence intervals (CIs) were pooled to quantify this relationship. Fifty eligible studies with a total of 3,068,244 participants and 6508 HIV-infected cases were included. The overall analysis found that blood group AB increased the risk of HIV infection by 19% as compared with non-AB blood groups (RR=1.19, 95% CI: 1.03-1.39, p=0.02). Pooled estimates for other blood groups failed to reach statistical significance. Subgroup analyses identified a positive relationship between AB blood group and HIV infection within Asia, patient populations (as opposed to blood donors and general populations), studies with lower sample sizes, high-income countries and studies with a moderate quality score. The sequential omission and re-analysis of studies within sensitivity analyses produced no change in the overall pooled effect. In conclusion, this study identified that blood group AB carriers were more susceptible to HIV infection. Future investigations should be directed toward clarification of the exact role of ABO blood groups in HIV infection and the possible underlying mechanisms.

Variations of prothrombin time among ABO blood groups in healthy adults

Background and objectives: ABO blood group distribution defers with racial and geographic variations. They are related with diseases like cardiovascular diseases, cerebral thromboembolism. Prothrombin time may varies among ABO blood group system which may increase the future risk of thrombosis. The present study is to assess prothrombin time among ABO blood groups in healthy adults. Materials and methods: A prospective type of analytical cross-sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2019 to June 2020. After obtaining ethical clearance, a total 190 healthy adults were selected from different areas of Dhaka city based on inclusion and exclusion criteria, with age ranging from 18-45 years. The subjects were interviewed and detailed history regarding personal, family, medical and drug were taken. Prior to sample collection, informed written consent was taken from the participants. Individuals of blood group A was selected as group A, blood group B as group B, blood group AB as group AB and blood group O as group O. Prothrombin time was measured in the Department of Hematology and BMT Unit, Dhaka Medical College Hospital, Dhaka. Blood grouping was done in the Department of Physiology, Dhaka Medical College, Dhaka.For statistical analysis, One way ANOVA followed by Bonferroni test were considered using SPSS 25.0 version. Results: In this study, blood group B was most common (33.2%). Prothrombin time was lower in blood group A (12.93±0.30 sec), B (12.92±0.61 sec), AB (12.98±0.54 sec) than blood group O (13.08±0.39 sec) which was not statistically significant. Conclusion: It can be concluded that blood group A, B, AB individuals may have more chance of thrombosis due to lower prothrombin time than blood group O individuals.

Distribution of ABO and Rhesus Blood Group Phenotypes Among Blood Donors at Bahir Dar Blood Bank, Amhara, Northwest Ethiopia: A Retrospective Cross-Sectional Study.

BackgroundAmong the blood group antigens identified, ABO and Rhesus are the most important in transfusion medicine. ABO blood group antigens are the most immunogenic followed by Rhesus (D antigen). These blood groups’ frequency distribution varies among different regions and races of the world. This study aimed to identifying the frequency distribution of ABO blood group and rhesus factors among blood donors in Ethiopia.Methods and MaterialsAretrospective cross-sectional study was conducted from September 12/2019 to March 18/2021 at Bahir Dar blood bank service. After getting a permission letter from the blood bank, data were collected from the blood bank donor data registration system, and descriptive statistical results were presented in number (frequency) and percentage. A Chi-square test was used to show the difference in the frequency distribution of ABO and Rh blood groups among sex and blood donation site.ResultsFrom 40,053 blood donors, 67.7% were males and younger donors (within the age range of 18–24 years) account for 63.7%. All donations were from voluntary non-remunerated blood donors. The most common blood group was blood group O (41.5%) followed by A (29.8), B (23.2%), and AB (5.5%). Considering ABO and Rh blood group altogether blood group O positive with 37.9% was the predominant blood group followed by A positive (27.2%), B positive (21.4%), AB positive (5%), O negative (3.6%), A negative (2.6%), B negative (1.8%), and AB negative (0.4%). The majority of study participants were 91.5% Rh (D) positive.ConclusionThis study showed that blood group O was the predominant followed by A, B, and AB and most of the blood donors’ blood groups were Rh-positive (91.5%). About 68.9% of the total donations were from the first time donor.

Could the ABO Blood Group Types be Associated with COVID-19 Mortality?

Aim: Currently, it is still a matter of debate whether a particular blood types is associated with an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In the present study, we aimed to evaluate the relationship between the ABO blood group types and mortality in patients hospitalized with the diagnosis of Coronavirus disease-2019 (COVID-19). Methods: This cross-sectional study included 427 patients diagnosed with COVID-19 between March 2020 and June 2020. SARS-CoV-2 ribonucleic acid was investigated in the naso/oropharyngeal swab samples of the patients by polymerase chain reaction. The blood group types, clinical and demographic data of the cases were obtained from the hospital automation system and patient files. Results: The age range of the patients was between 18 and 96, and 53.4% (228/427) of them were male. The ABO blood group distribution was 47.1% A, 29.5% O, 15.9% B, 7.5% AB. The overall mortality rate of COVID-19 cases was 16.9%. COVID-19 mortality risks were not significant in any of the ABO blood group types. Conclusion: We did not find a significant relationship between blood group types and mortality in patients who were hospitalized with a diagnosis of COVID-19 and received treatment and follow-up. [ABSTRACT FROM AUTHOR] Copyright of Medical Bulletin of Haseki / Haseki Tip Bulteni is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Genotyping of ABO and Duffy blood groups among malaria patients in Thailand.

ABO blood groups have been proposed to influence malaria parasite infection and disease severity in individuals residing in different geographical areas. In Thailand, genetic polymorphisms of blood groups and susceptibility to malaria infection have rarely been investigated. The aim of this study was to assess the genotype frequencies of ABO and Duffy blood groups and susceptibility to malaria infection in two populations residing in malaria-endemic areas of Thailand. 1100 malaria samples and an identical number of samples from healthy subjects were collected from Thai-Malaysian and Thai-Myanmar areas. Genotyping of ABO and Duffy blood groups was performed by sequence specific primer-polymerase chain reaction. The distribution of ABO and Duffy blood groups was similar in malaria-positive and negative subjects. Blood group O was prevalent in both populations followed by blood group B (BO genotype) and A (AO genotype), respectively. In Plasmodium falciparum infections, blood group A frequency was significantly higher in Thai-Malaysian samples (P = 0.042) whereas blood group B frequency was significantly higher in Thai-Myanmar samples (P = 0.022). FY*A/*A frequency was significantly higher in Plasmodium vivax infection (P = 0.036) while FY*A/*B frequency was significantly higher in healthy subjects (P = 0.005). The different ABO blood group frequencies in the two populations may contribute to susceptibility to P. falciparum infection and the high prevalence of FY*A/*A can confer a risk of P. vivax infection. Further research in various ethnic groups is needed to clarify the association between blood groups and pathogenesis of malaria.

Prognostic relevance of ABO blood group system in non-metastatic renal cell carcinoma: An analysis of two independent European cohorts with long-term follow-up

BackgroundThe ABO blood group system has been previously discussed as a risk factor to develop, as well as a prognostic factor in non-metastatic renal cell carcinoma (RCC). Controversial findings have been reported in different populations of RCC patients with rather short follow-up periods. In this study, we aimed to clarify the distribution and prognostic role of ABO blood groups upon 15 years of median follow-up in non-metastatic RCC patients. Materials and methodsWe evaluated the distribution and prognostic significance of ABO blood group system in two independent cohorts (n = 405 and n = 1473) of non-metastatic RCC patients, who underwent curative (partial or total) nephrectomy between 1998 and 2012 at two tertiary academic centers. Cancer-specific survival, metastasis-free survival, as well as overall survival (OS) were assessed using the Kaplan-Meier method, univariable- and multivariable Cox regression models were applied, respectively. ResultsIn the two cohorts, blood groups were not associated with any clinical endpoints (for cohort 2: Cancer-specific survival (HR = 1.233; 95%CI 0.998–1.523, P = 0.052), metastasis-free survival (HR = 1.161; 95%CI 0.952–1.416, P = 0.142) and OS (HR = 1.037; 95%CI 0.890–1.208, P = 0.641), respectively). Compared to 250.298 healthy blood-donors of the Styrian state, the distribution of blood groups was (624 (42.4%) versus 106.861 (42.7%) in group A, 191 (13%) vs. 34.164 (13.7%) in group B, 575 (39%) versus 93.579 (37.4%) in group O and 83 (5.6%) vs. 15.694 (6.3%), P = 0.467). ConclusionIn this large study with the longest period of follow-up reported to date, the ABO blood group system could not be validated as a prognostic factor in predicting important clinical endpoints in non-metastatic RCC patients.

ABO and Rhesus Blood Group Distribution and Blood Donation Willingness Among First-Year Health Students in a Saudi University.

BackgroundUnderstanding the distribution of blood groups and blood donation willingness in a population is crucial in managing blood banks and transfusion services. Moreover, awareness of one’s own blood group is essential especially in emergencies that mandate blood donation. This study aimed to determine the distribution of ABO and Rhesus (Rh) blood groups among health students, the students’ knowledge about their blood group, and their willingness to donate blood.MethodsThis cross-sectional study included all newly accepted health students in a large university in the Eastern Province of Saudi Arabia (N=1145) during August 2020. The data included a self-administered questionnaire and the serology results of ABO and Rh factors. Chi-squared and Fisher’s exact tests were performed followed by a multivariable binary logistic regression analysis which identified the predictors of willingness of blood donation.ResultsBlood group O was the most frequent type among students (51.1%), followed by group A (24.5%) and B (20.4%). The majority (93.3%) of students had Rh-positive factor. When we compared students’ answers with their sample results, most students (75.5%) correctly reported their ABO and Rh blood groups. Male students and those with a previous history of blood donation correctly reported their blood group more than others. Of the total sample, 47.3% were willing to donate blood within the next year. Positive predictors of the willingness of student to donate blood included being male, and those with a history of blood donation. Interestingly, students with a family member in the healthcare field were significantly less likely to donate blood.ConclusionBlood group O and Rh positive were the most frequent blood groups. Most students had a good knowledge about their blood groups, and about half of students were willing to donate blood. Efforts to encourage the young population to participate in blood donation are crucial.

Relationship between ABO blood groups and gestational hypertensive disorders: A protocol for systematic review and meta-analysis.

Background:The distribution of ABO blood group is related to the incidence of various diseases. Gestational hypertensive disorders (GHD) is one of the most important risk factors during pregnancy, which has certain heredity. It is reported that ABO blood type is associated with the risk of GHD. However, the results are still controversial. In this study, we conducted a systematic review and meta-analysis to clarify the relationship between ABO blood group and GHD.Methods:All eligible studies come from Embase, Cochrane Library, Pubmed, Chinese databases SinoMed, Chinese National Knowledge Infrastructure, Chinese Scientific Journals Database, and Wanfang Data. The retrieval time is from the establishment of the database to March 2021. The language will be limited to Chinese and English. The 2 reviewers will be responsible for the selection of the study, the extraction of data, and the evaluation of the quality of the research. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the corresponding associations. Sensitivity analysis, publication bias assessment, and heterogeneity test were performed using STATA 16.0.Results:The results of this meta-analysis will be published in peer-reviewed journals.Conclusion:This study will provide evidence to support the relationship between ABO blood group and the risk of GHD.Ethics and dissemination:The private information from individuals will not be published. This systematic review also will not impair endangering participants’ rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences.OSF Registration number:DOI 10.17605/OSF.IO/3X9YZ.

ABO blood groups and liver cancer: prospective results from an HBsAg cohort study

ObjectiveThe association between ABO blood group and risk of liver cancer is unclear, although few studies have reported positive results. This study examined the relationship between ABO blood group and...