The emergence of infectious diseases and global pandemics necessitates continuous advancements in health surveillance and preparedness strategies. This article explores the innovations in global health that leverage technology to enhance disease surveillance and improve pandemic preparedness. The study investigates the role of various technological solutions, including artificial intelligence, data analytics, mobile applications, and digital communication platforms, in strengthening global health systems. The article reviews recent case studies and initiatives where technology has been successfully employed for disease surveillance, early detection of outbreaks, and rapid response to emerging health threats. It examines how digital tools facilitate real-time data collection, analysis, and dissemination, enabling more effective monitoring of infectious diseases globally. Additionally, the article discusses the integration of wearable devices, telemedicine, and other remote health technologies in enhancing the resilience of health systems during pandemics. Furthermore, the challenges and ethical considerations associated with the implementation of technological innovations in global health are critically assessed. Privacy concerns, data security, and the need for global collaboration are addressed to ensure the responsible and ethical use of technology in disease surveillance. The article concludes by highlighting the potential of technology to revolutionize global health practices, emphasizing the importance of collaborative efforts among governments, international organizations, and the private sector. As the world faces ongoing and emerging health threats, the adoption of innovative technological solutions becomes paramount for building robust disease surveillance systems and improving overall pandemic preparedness on a global scale.