Diabetes is one of chronic diseases in which blood glucose (sugar) level soar up high where human body are incapable to absorb it properly. It is important to have an appropriate diagnosis for proper management and treatment. The aim of this manuscript is to provide a more accurate diabetes prediction model through the new adaptive Trapezoidal Neutrosophic Teaching Learning-Based Optimization (TLBO) method. In order to address the inherent uncertainties and imprecisions in medical data, the suggested model makes use of the resilience of Trapezoidal Neutrosophic sets. The Trapezoidal Neutrosophic set theory provides a suitable basis for developing rule/knowledge-based systems in the medical field. The present investigation makes use of the dataset acquired from the Pima Indians Diabetes Database (PIDD) website, which has an extensive global collection of diabetes datasets. The performance of our model is evaluated against several existing methodologies, including Intuitionistic Neuro-Fuzzy System (INFS) Structure, Fuzzy Logic based Diabetes Diagnosis System (FLDDS), Fuzzy Verdict Mechanism (FVM) for Diabetes Decision, (Fuzzy Expert System) FES, and Hierarchical Neuro-Fuzzy Binary space partitioning System (HNFB-1). Quantitative analysis validates that proposed methodology achieves an exceptional predictive accuracy of 99.89 %, which is substantially higher than the comparative methodologies, namely INFS Structure (88.76 %), FLDDS (87.2 %), FVM for Diabetes Decision (85.03 %), FES (81.7 %), and HNFB-1 (78.26 %). These enhancements demonstrate show how well the suggested model works to lower diagnostic errors and increase dependability.