Although railway axles are a crucial part of railway vehicles, they are susceptible to long-term failure because of repeated loads. The aim of this research is to investigate the stress intensity factor (SIF) of a surface elliptical crack on a high-speed railway axle under various operating conditions. The study employs numerical analysis to explore the impact of press-fitting, rotary bending, stable and adverse running conditions on the SIF solutions. The main findings demonstrate that adverse running conditions, such as the press-fitting force, asymmetric vehicle weight, lateral force and wheel-rail contact force, can significantly increase the SIF values and result in axle failure. The press-fitting effect and rotary bending also have a significant impact on the SIF values, highlighting their importance in the railway axle design and analysis. The outcome of this research emphasizes the significance of accurately estimating SIF values to ensure the safe and reliable performance of railway axles in adverse operating conditions.