You have accessJournal of UrologyEducation Research I (PD02)1 Sep 2021PD02-07 RESIDENT'S LEARNING CURVE OF MRI/TRUS TARGET PROSTATE FUSION BIOPSY AFTER MORE THAN 1000 PROCEDURES Enrico Checcucci, Federico Piramide, Sabrina De Cillis, Daniele Amparore, Gabriele Volpi, Alberto Piana, Stefano Granato, Angela Pecoraro, Paolo Alessio, Beatrice Carbonaro, Juliette Mézière, Giovanni Cattaneo, Francesca Ragni, Matteo Manfredi, Cristian Fiori, and Francesco Porpiglia Enrico CheccucciEnrico Checcucci More articles by this author , Federico PiramideFederico Piramide More articles by this author , Sabrina De CillisSabrina De Cillis More articles by this author , Daniele AmparoreDaniele Amparore More articles by this author , Gabriele VolpiGabriele Volpi More articles by this author , Alberto PianaAlberto Piana More articles by this author , Stefano GranatoStefano Granato More articles by this author , Angela PecoraroAngela Pecoraro More articles by this author , Paolo AlessioPaolo Alessio More articles by this author , Beatrice CarbonaroBeatrice Carbonaro More articles by this author , Juliette MézièreJuliette Mézière More articles by this author , Giovanni CattaneoGiovanni Cattaneo More articles by this author , Francesca RagniFrancesca Ragni More articles by this author , Matteo ManfrediMatteo Manfredi More articles by this author , Cristian FioriCristian Fiori More articles by this author , and Francesco PorpigliaFrancesco Porpiglia More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001966.07AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: During last years, prostate cancer (PCa) detection has been improved by the implementation of software allowing to perform MRI-transrectal ultrasonography fusion-guided prostate biopsy (MRI/TRUS fusion biopsy, FB). The aim of our study was to assess the learning curve (LC) of two urology residents in the execution of fusion biopsy (FB) considering overall prostate cancer (PCa) and clinically significant (cs) PCa detection rate (DR), based on different lesions’ characteristics at the MRI. METHODS: We extracted data from our prospectively maintained database from January 2015 to December 2019. FB was carried out with the BioJet fusion system (D&K Technologies, Barum, Germany) either by a transrectal or transperineal approach. An ANOVA test was used to assess the homogeneity of the cohort. Multivariable linear and logistic regression analysis were used to assess the correlation between operator experience and DR for PCa and csPCa. At last, the postprocedural complication rate trend was determined. RESULTS: 1005 men were enrolled in the study. During the five years of the study, the pre-biopsy characteristics of the patients enrolled did not change significantly except for the proportion of patients who previously underwent prostate biopsy (p<0.001) and the number of mpMRI performed at referral centers (p=0.002), both showing a decreasing trend over time. The overall DR of PCa was 61.2% (615/1005) [IC 0.58-0.64]; whilst DR for csPCA was 54.6% (549/1005) [IC 0.51–0.57]. Operator experience does not appear to impact the DR of overall PCa and csPCa. On the contrary, in case of lesions with diameter <8 mm, PCa and csPCa DR were significantly higher with operator experience (p=0.048 and p=0.038, respectively). Considering the suspicious tumours located in the more challenging areas of the prostate (transitional or posterolateral zone) were not significantly better diagnosed with experience improvement (p=0.34 and p=0.22 for PCa DR and csPCa DR respectively). The specific analysis focused on PI-RADS 5 lesions, mpMRI performed in referral centers, or for patients at repeated-biopsy did not reveal a significant relationship between operator experience and PCa or csPCa DR. Complication rate was stable during the whole study (p=0.75). CONCLUSIONS: A standardized FB approach demonstrated to be feasible, safe, and effective since the start of residents’ LC. PCa and csPCa DR was stable, after > 1000 biopsies. Nevertheless, in case of lesions < 8 mm, the execution of at least 100 FB is fundamental in order to correctly sample the area. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e40-e40 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Enrico Checcucci More articles by this author Federico Piramide More articles by this author Sabrina De Cillis More articles by this author Daniele Amparore More articles by this author Gabriele Volpi More articles by this author Alberto Piana More articles by this author Stefano Granato More articles by this author Angela Pecoraro More articles by this author Paolo Alessio More articles by this author Beatrice Carbonaro More articles by this author Juliette Mézière More articles by this author Giovanni Cattaneo More articles by this author Francesca Ragni More articles by this author Matteo Manfredi More articles by this author Cristian Fiori More articles by this author Francesco Porpiglia More articles by this author Expand All Advertisement Loading ...