‘‘Audiobook” is a multimedia-based reading technology that has emerged in recent years. Realizing the alignment of e-book text and book audio is the most important part of its processing. This article describes an audio and text alignment algorithm using deep learning and neural network technology to improve the efficiency and quality of audiobook production. The algorithm first uses dual-threshold endpoint detection technology to segment long audio into short audio with sentence dimensions and recognizes it as short text. The threshold is calculated by AIC-FCM optimized based on simulated annealing genetic algorithm. Then the algorithm uses Doc2vec optimized by the threshold prediction method based on the average length of the short text to calculate the text similarity. Finally, proofread and output the text sequence and audio segment aligned in the time dimension to meet the needs of audiobook production. Experiments show that compared to traditional audio and text alignment algorithms, the proposed algorithm is closer to the ideal segmentation result in long audio segmentation, and the alignment effect is basically the same as Doc2vec and the time complexity is reduced by about 35%.