The purpose of the current research was to evaluate the impact of various denture cleaners on the surface hardness of permanent silicone denture lines. In the present study, 124 specimens were included comprising of soft liners made of permanent silicone, which were made from the 15 mm x 10 mm custom metal mold dimensions, where 62 samples were made of Molossil™ and 62 other of Voco™ which are commercially available liners for permanent dentures. These samples were then divided into 4 groups of equal specimen numbers (n=32) depending on the cleansing treatments. Group I specimens were cleaned with water daily, and Group II Polident™ Group III was given SecureTM denture cleaning solution, while Group IV was given PeriogardTM denture cleaning solution. The samples were assessed at 1st week, 1st month, and 6th month after cleanser use. The study results showed that at the 6th-month follow-up after the use of denture cleansers, all of the samples had considerably increased surface hardness compared to the baseline. Statistically significant results were seen with Periogard™, Secure™, and Polident™ compared to Group I controls. In Voco™ denture liners, minor changes were seen compared to Molossil™ soft liners with time in all the groups. The results of this investigation are significantly well cleansing action is seen with Voco™ soft denture lining material compared to Mollosil™ soft denture lining material, and surface hardness is least affected by Polident™ denture cleanser compared to Secure™ and Periogard™ denture cleansing agents.
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