Hybrid resin block for CAD/CAM are known as useful material for clinical use. In last year, hybrid resin crown for CAD/CAM restoration in anterior teeth was approved by Japanese national health insurance. Recently we launched highly aesthetic resin block CERASMART LAYER only in Japan. CERASMART LAYER can materialize an aesthetic appearance close to natural teeth because it has three-layered composition. The purpose of this study was to evaluate aesthetic properties of the new material and other products in the marketplace. Five materials were selected for experimental and analysis, 1) CERASMART LAYER (GC Corp.), 2) KATANA AVENCIA N (Kuraray), 3) KZR-CAD HR Block4 E-VA (YAMAKIN), 4) HC HARD AN (SHOFU), 5) ENAMIC Multicolor (VITA). These blocks were evaluated by Tooth-brush test. The specimen of tooth-brush test was formed into anterior teeth shape by using Cerec inLab MC XL (Dentsply Sirona) and was recontoured and polished in accordance with instructions. The specimen was placed in silicone mold in order to define the position of abrasion by brush. The test was conducted with tooth-brush machine for 12,000 cycles. The surface morphology of specimens before and after test was investigated with laser microscope (KEYENCE) and evaluated surface roughness (Ra value). All results were analyzed by one-way ANOVA (p<0.05). The results of tooth-brush test, CERASMART LAYER showed the lowest Ra value after 12,000 cycles of tooth-brush abrasion because of uniformly dispersion and high loading of inorganic nano-filler. In addition, only CERASMART LAYER and KATANA AVENCIA N showed glossy surface in spite of after 12,000 cycles of tooth-brush test. From the results, CERASMART LAYER exhibited the lowest surface roughness and highly gloss retention. Therefore, it is expected that CERASMART LAYER is a durable and aesthetic material and may have clinical advantages.