Objective: To develop and evaluate a smartphone application with web application tool, content management, that enables the study of radiographic anatomy. Study Design: Face-to-face meetings and design thinking activities were carried out to better understand the proposed problem by the research group. The application, completed in the beta version, provided satisfaction and usability questionnaires to 51 students of the dentistry course. Results: A total of 50% of students use the Android operating system; 100% of the students feel that applications can aid in the teaching of radiology, 93.20% prefer to study by photos, and 86.40% study with the cell phone connected. Regarding the satisfaction questionnaire, with the APPOLO app (app of learning on line), Cronbach alpha coefficient was applied, obtaining values above 0.7; therefore, the questionnaire is reliable. In addition, 98.04% affirmed that it the content that is made available is certainly important. A total of 64.69% of the students considered the quantity of the images satisfactory. The majority, 68.62%, feel very motivated to complement their study with this type of methodology. As for the usability of the application, 66.66% found its handling very easy. Conclusion: The APPOLO application proved to be practical and easy to understand, navigate, and use; further, it can assist in the teaching support of students of dental radiology. Objective: To develop and evaluate a smartphone application with web application tool, content management, that enables the study of radiographic anatomy. Study Design: Face-to-face meetings and design thinking activities were carried out to better understand the proposed problem by the research group. The application, completed in the beta version, provided satisfaction and usability questionnaires to 51 students of the dentistry course. Results: A total of 50% of students use the Android operating system; 100% of the students feel that applications can aid in the teaching of radiology, 93.20% prefer to study by photos, and 86.40% study with the cell phone connected. Regarding the satisfaction questionnaire, with the APPOLO app (app of learning on line), Cronbach alpha coefficient was applied, obtaining values above 0.7; therefore, the questionnaire is reliable. In addition, 98.04% affirmed that it the content that is made available is certainly important. A total of 64.69% of the students considered the quantity of the images satisfactory. The majority, 68.62%, feel very motivated to complement their study with this type of methodology. As for the usability of the application, 66.66% found its handling very easy. Conclusion: The APPOLO application proved to be practical and easy to understand, navigate, and use; further, it can assist in the teaching support of students of dental radiology.