GREAT interest has been manifested in gall-bladder disease, especially since the advent of cholecystography, for this method of diagnosis has led to a far more accurate study of affections present in the upper right quadrant of the abdomen. In the roentgenographic examination of the gall bladder, the liver shadow is usually well outlined, though heretofore little attention has been paid to actual measurements. However, in the routine gastro-intestinal roentgen examination it is usually customary, whenever possible, to report the size of the liver as being normal, slightly enlarged, moderately enlarged, or markedly enlarged, together with a statement of the number of finger-breadths or centimeters of its position below the costal margin. Since these terms are only relative, it would seem far more satisfactory, as well as accurate, if the actual measurements could be determined. In many instances the liver shadow is visualized more satisfactorily before than after the administration of tetraiodophenolphthalein; more frequently, however, the outline becomes clearer following the administration of the dye. On the other hand, the lower margin of the liver frequently shades off towards the kidney and other structures, thus making it difficult to secure proper measurements. Pfahler (1), in a recent study of liver measurements, demonstrated the average length of the right lobe to be 21.3 cm. and the average thickness 12.8 cm. In attempting to standardize this method to determine the size of the liver the following technic has been used. The subject is placed in the supine position on the Potter-Bucky diaphragm and a 14 × 17 film taken, which includes both kidneys and spleen. Two measurements are secured: one, the “length,” measured from the highest point of the upper border to the tip of the right lobe; the second measurement, “thickness,” is measured from the upper to the lower border in an oblique direction. In our study an attempt is made to compare and correlate the size of the liver with regard to the gall-bladder pathology as determined by the gall-bladder visualization test. Technic The method followed is the usual gall-bladder technic, the patient lying on the abdomen on the Potter-Bucky diaphragm. A series of films is made of the gall bladder, which also includes the liver, a method which does not require an additional examination for liver measurement. The films are taken in both inspiration and expiration and movements of the liver, together with the diaphragm, are noted during respiration. This organ will be observed to be lower in deep inspiration and higher in deep expiration. The measurement of the liver in this series is made from four fixed anatomical points, differing somewhat from that advocated by Pfahler. Only the right lobe of the liver is measured. The left lobe is not usually visualized, as it is overshadowed by other structures. (1) Vertical measurement; from the upper to the lower border in the nipple line.