This study aimed to determine the role of the most important practices of human resources, represented by their dimensions (training and development, career development, recruitment, and selection) in enhancing the effectiveness of the following comprehensive quality management practices (continuous development, customer focus, and continuous pursuit of customer opinions). in the Colleges of Education for Humanities and Pure Sciences. This goal was translated into a hypothesis drawing that included the study variables, the dependent variable represented by total quality management, according to the exploratory descriptive approach, and its hypotheses were formulated, and then the research hypotheses were formulated and tested using appropriate mathematical statistical methods and using the statistical package program (SPSS). Thus, the theoretical and then analytical framing was used to test the research hypotheses, where the study population consisted of employees in the College of Education for Pure Sciences and Humanities at the three administrative levels, and the sample size was (94) individuals from directors, directors of departments, divisions, units, and administrative employees. The research reached several conclusions, the most important of which was the existence of a significant correlation to the role of human resources management practices, including their dimensions, and the effectiveness of total quality management in the sample studied. Finally, the research recommendations came out with the need to pay attention to providing an appropriate basis for human resources practices for new operations by making structural changes, enhancing cooperation processes, and using appropriate sources in order to advance, maintain survival, continuity, and develop the effectiveness of total quality management