Extract Of Coriandrum Sativum Research Articles

Anti-stress and Nootropic Activity of Ethanolic Extract of Coriandrum sativum Aerial Parts

The swimming endurance test, anoxic tolerance test, and basal activity by actophotometer were used to assess the antistress activity of a seven-day therapy (200 and 400 mg/kg, p.o.) of the ethanolic extract of Coriandrum sativum (EECS) aerial parts. A method for measuring the in vitro antioxidant activity of hydroxyl radicals was used. In all of the examined models, Coriandrum sativum at both doses demonstrated antistress effects. In the anoxic tolerance test, swimming endurance test, and duration of stay on the rotarod, the EECS treated rats demonstrated enhanced swimming time, duration, and anoxic tolerance time, respectively. The C. sativum's potential to scavenge free radicals, which enhanced the cognitive effect, was utilized to determine the in vitro antioxidant activity. The results demonstrated clearly that the extract's in vivo adaptogenic performance and cognitive improvement were caused by its in vitro antioxidant activity. The EECS treated animals showed increase locomotor scores in basal activity by Actophotometer. The plant secondary metabolites flavonoids, glycosides, triterpenoids, and phenolic components may be accountable for the animals' improved swimming endurance, stress tolerance, and overall performance. This study gave evidence that the ethanolic extract of Coriandrum sativum has antioxidant, anti-stress, and nootropic activity, and that utilizing them by humans as nutraceuticals is beneficial and scientific. By stress reduction in animals, the antioxidant effect provides the pharmacological basis for supporting a healthy memory.

Synergistic antioxidant activity of selected medicinal plants in Brunei Darussalam and its application in developing fortified pasta.

Developing functional foods by utilizing plants can often lead to compromised sensory properties. Thus this study investigates the combination of plants to produce synergistic effects and to incorporate these plant powders into a pasta formulation without affecting its sensory acceptance. Six common Brunei medicinal plants were evaluated for their in vitro antioxidant activity determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (IC50 ), ferric reducing antioxidant power (FRAP) assay and 2,2'-azino-bis(3-ethylbenziazoline-6-sulfonic acid) (ABTS) radical scavenging assay. Aqueous extracts of Amaranthus tricolor, Breynia androgyna, Manihot esculenta, Polygonum minus, Apium graveolens and Coriandrum sativum were prepared. Breynia androgyna had the highest FRAP value of 74.3 ± 5.33 mg g-1 ascorbic acid equivalents (AAE), with DPPH IC50 antioxidant activity of 70.3 ± 3.14 μg mL-1 and ABTS scavenging activity of 44.0 ± 2.80 mg g-1 AAE. This correlates well with the total flavonoid, flavonol and phenolic content (50.5 mg g-1 gallic acid equivalents (GAE), 50.6 mg g-1 GAE and 24.3 mg g-1 GAE, respectively). Plant species powders were combined in pairs and evaluated for their synergistic antioxidant properties. With potential synergistic plant mixtures, fortification of these mixtures into functional food can be developed to improve its overall antioxidant capacity. Based on the synergistic IC50 results of these mixtures, three fortified pastas were formulated by incorporating selected plant powder combinations of Amaranthus tricolor + P. minus, Apium graveolens + P. minus, and P. minus + B. androgyna into wheat pasta at 1:100 (w/w). Fortification of pasta with the plant powder blends resulted a significant increase in DPPH antioxidant activity, while successfully maintaining indistinguishable features from the control pasta, including minimal cooking loss, agreeable measure of cohesiveness, springiness and chewiness, with good overall sensory acceptability. © 2022 Society of Chemical Industry.

Therapeutic Validation of Coriandrum sativum Extract in Emesis and Analgesia

In the traditional System of Medicine, the leaves and seeds of Coriandrum sativum are used usually as emollient, antii-flammatory, stom-achic, carmi-native, digestive, constipating, astringent, antipyretic, diuretic, appetizer, stimulant, refrigerant, tonic, expectorant, in dyspepsia etc. The aim of this study was to investigate antiemetic and analgesic activity of the whole plant extract of Coriandrum sativum in Wister albino rats and chick emesis models. The anti-emetic activity of the Coriandrum sativum is determined by using the chick emesis model. Antiemetic activity of Coriandrum sativum is determined by percentage inhibition of retching that is tempted with the help of copper sulfate. Copper sulphate is used to persuade emesis in chick. Analgesic activity is established by using the Wister albino rat as an experimental animal. Acetic acid is used to induce writhing in animals. The plant extract decreases the dose dependent writhing in acetic acid induced analgesia in Wister albino rats.

ANTI-INFLAMMATORY AND ANTI-CANDIDAL ACTIVITY OF CORIANDRUM SATIVUM SEED EXTRACTS AGAINST CANDIDA ALBICANS AND CANDIDA TROPICALIS

Background: Candidiasis in not uncommon among hospitalized patients. The fungal virulence and antifungal drug resistance make the host-parasite interactions complicated. The threat of azole drug resistance along with scarcity of antifungal therapies prompted the necessity of novel drug development from various natural sources. The objective of this study was to evaluate the anticandidal activity of Coriandrum sativum seed extracts against Candida albicans and Candida tropilcalis. Materials & Methods: This study was conducted at Department of Basic Medical Sciences, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia from July 20, 2021 to September 26, 2021. The study analyzed anti-inflammatory assays via inhibition of albumin denaturation and hemolysis inhibition and anticandidal activity of the extract against Candida albicans and Candida tropilcalis by well diffusion method. The minimum inhibitory concentration (MIC) of the extract was also determined against both the fungi. Results: Anti-inflammatory activity of Coriandrum sativum methanolic seed extracts were evaluated at five different concentrations from 100 µg to 1000 µg. The highest concentration showed 55.31±0.77% of inhibition of albumin denaturation, whereas the aspirin, the standard used, showed 80.33±0.32%. Coriandrum sativum seed extracts at 250 mg/ml, 500 mg/ml and 1000 mg/ml produced zones of growth inhibition with diameters 12.66±0.57, 17.66±0.57 and 24.33±1 mm against Candida albicans, and 10.33±0.57, 16.66±0.57 and 21.66±0.57 mm against Candida tropicalis. The MICs of the Coriandrum sativum seed extracts against Candida albicans was 1.95 mg and Candida tropicalis was 3.9 mg. Conclusion: Phytochemical compounds in methanolic seed extracts of Coriandrum sativum showed significant anticandidal activity against Candida albicans and Candida tropicalis with highest zone of inhibition at 1000 µg extract concentration. The lower MICs of Coriandrum sativum seed extracts against Candida albicans and Candida tropicalis were also significant. Considering all these findings along with the antioxidant activities, it could be suggested that Coriandrum sativum seed extracts can further be investigated for development of novel anticandidal drugs.

PROTECTIVE EFFECT OF CORIANDRUM SATIVUM L. (CORIANDER) ETHANOLIC LEAF EXTRACT ON ISONIAZID INDUCED HEPATOTOXICITY IN ALBINO MICE

Objective: To study the antioxidant effects of ethanolic extract of coriander leaves on INH induced hepatotoxicity.
 Methods: Total 27 male albino mice were randomly divided through balloting into three groups containing nine animals each. Group A served as control while INH toxicity was produced by oral administration (INH 100mg/kg) to group B. Hepatoprotectivity was investigated by co-administration of single oral dose of ethanolic extract of coriander leaves (200mg/kg) along with INH in groups C for 30 days.
 Results: On gross examination, liver of group C animals were found to be normal. Biochemical analysis of liver markers of group B showed that these enzymes were markedly raised while experimental group C showed significant decreased level of liver enzymes. Histological examination of group C revealed normal histology with little evidence of inflammation, vascular congestion, necrosis, pyknosis, apoptosis and vacuolar degeneration as compared to group B. 
 Conclusion: This study showed the ameliorating effect of ethanolic extract of Coriandrum sativum L. against INH induced hepatotoxicity.

Dermal toxicity and wound healing activity of Coriandrum sativum L. leaves extract and its formulated ointment in wistar rats

Wound is referred as any physical injury that breaks the skin layer. Wound healing is known as the regeneration of tissues whereby the new layer of skin is formed. Wound healing follows a cascade of events starting with homeostasis, inflammation, proliferation and remodeling of tissues. Although there were many studies have been conducted proving various traditional plants exhibiting wound healing properties but wound healing properties of coriander leaves were limited. Therefore, this research was conducted to determine the wound healing activity using the extract of Coriandrum Sativum L leaves (CSL) using formulated ointment in Wistar rats. CSL were extracted successively using methanol in a soxhlet extractor for 36 hours at 60°C. Skin toxicity was done on rats. For screening excision wound, animals were divided into four groups (n=6). Group-1 is treated with vehicle (control). Group-2 and 3 were treated with 10% and 20% of extract ointment respectively. Group-4 was treated with standard Betadine ointment. Methanolic extract of C. sativum L. (MECS) was applied topically on the excision wound of the rat for two times per day. The parameter observed were percentage of wound contraction. ANOVA test was used to analyze the results obtained for excision wound was statistically significant (P<0.05). The MECS extracts with 20% extract has shown a significant wound-healing activity that was supported by decrease in the period of epithelialization and also increase in rate of contraction of wound in experimental animals. The MECS extracts have proved to possess wound healing properties and a higher concentration of the extract has facilitated as a good choice of remedy for woundhealing.

Green synthesis and characterization of iron oxide nanoparticles using Coriandrum sativum L. leaf extract

Green nanoparticle synthesis is a promising, eco-friendly and safe approach. In the current study, Iron oxide nanoparticles (FeONPs) were synthesized using aqueous leaf extract of Coriandrum sativum L. Further, the characterization of synthesized FeONPs was performed using ultraviolet-visible spectroscopy, transmission electron microscopy (TEM), dynamic light scattering (DLS), vibrating sample magnetometer (VSM) and differential scanning colorimetry (DSC). The surface plasmon resonance effect confirmed the synthesis of FeONPs. Dynamic light scattering (DLS) revealed mean particle size of FeONPs around 163.5 and polydispersity index 0.091 with a zeta potential of −13.8 mV. Differential scanning colorimetry (DSC) exhibited an endothermic peak at 176.91°C. Vibrating sample magnetometer (VSM) analysis showed superparamagnetic properties of iron nanoparticles with a magnetization value of 3.483 emu/g and the results indicated superparamagnetic behavior of prepared iron nanoparticles at room temperature, thus highlighting their potential as magnetically targeted drug delivery system. This biosynthetic method has been proven to be cost-effective, environment friendly and promising for use in biomedical sciences.

Analgesic Effect of Ethanolic Extract of Seeds and Leaves of Coriandrum Sativum on Swiss Albino Mice

INTRODUCTION: Pain has been described by the International Association for the Study of Pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Although NSAIDS and OPIOIDS are available for the treatment, still pain (chronic) is major problem. The present study was designed to study the analgesic effect of ethanolic extract of Coriandrum sativum using hot plate method and acetic acid induced writhing method in experimental animals (Swiss albino mice). MATERIAL AND METHODS:The analgesic effect of leaves and seeds of Coriandrum sativum was assessed using hot plate method and acetic acid induced writhing method in Swiss albino mice. The animals were treated with the ethanolic extract of leaves and seeds of Coriandrum sativum orally at two doses of 100, 500 mg/kg body weight after electric heat and acetic acid induced pain in mice. RESULTS: The study showed that ethanolic extract of leaves and seeds of Coriandrum sativum presented significant (p&lt;0.05) and (p&lt;0.05) analgesic activity in mice simultaneously. The data were analyzed by one-way ANOVA followed by Dunette's multiple comparison test. The results demonstrate that ethanolic extract of leaves and seeds of Coriandrum sativum has got analgesic potential. CONCLUSION: The results demonstrate that ethanolic extract of leaves and seeds of Coriandrum sativum has got significant analgesic effect.

Iron nanoparticles green-formulated by Coriandrum sativum leaf aqueous ‎extract: Investigation of its anti-liver cancer effects

IntroductionRecently, scientists have ‎understood that metallic nanoparticles especially iron nanoparticles have ‎excellent anticancer properties‎. A green, productive, and environmentally method was developed for the valuable study and the effective preparation of the biosynthesis of iron nanoparticles using aqueous extracts from the leaf of Coriandrum sativum as a result of reducing and stabilizing factor. The simplicity of the reaction, heterogeneous system, and easy work up are the benefits of the present method.Material and methodsThe as-prepared nanoparticles (FeNPs) was characterized using UV-Vis, SEM, and FT-IR. It has ‎been shown that the iron nanoparticles have spherical shape and uniform size.ResultsThe synthesized nanoparticles had very low cell viability and high anti-liver cancer activities ‎dose-dependently against pleomorphic hepatocellular carcinoma (SNU-387), hepatic ductal ‎carcinoma (LMH/2A), morris hepatoma (McA-RH7777), and novikoff hepatoma (N1-S1 Fudr) ‎cell lines without any cytotoxicity on the normal cell line (HUVEC). The synthesized ‎nanoparticles inhibited half of the DPPH molecules in the concentration of 132 µg/mL. Perhaps ‎notable anti-liver cancer activities of the synthesized nanoparticles against common liver cancer ‎cell lines are linked to their antioxidant activities. ‎ConclusionsOur results point out that the FeNPs from Coriandrum sativum extract are apposite stabilizing ‎agents, which serve as an effective anticancer agent against liver cancer cell lines.‎

Efficacy of Herbal Mouthwash with Extracts of Coriandrum Sativum, Mint and Clove in the Treatment of Chronic Gingivitis- A Randomized Controlled Clinical Trial

Introduction: Herbal antiseptic or antibiotic agents are introduced very widely that are effective against plaque microorganisms for the healing of gingival and periodontal tissue. However, none of literature has shown antibacterial effect of coriandrum sativum, clove and mint on the levels of dental plaque when used as a mouthwash.&#x0D; Aim: To assess the efficacy of a newly formulated mouthwash containing Coriandrum sativum, mint and clove to reduce plaque and inflammation to maintain the oral hygiene.&#x0D; Methodology: Twenty systemically healthy patients were randomly allocated to either the test group [G1(coriandrm sativum, mint,clove = 10 patients)] or the control group [G2 (Placebo gel = 10 patients]. Full mouth Gingival Index (GI); Full mouth Plaque Index (PI) was evaluated at baseline and on 14 and 21st day. &#x0D; Result: The mean reduction in PI from 2.28 to 0.85 and 2.13 to 1.21 was noted in the experimental and control groups, respectively. The experimental group (2.21–0.76) comparatively showed better reduction in mean PBI than the control group (2.17–1.29). The results obtained were statistically significant at baseline and 14th and 21st day in all the groups. Remarkable improvement was noted from baseline to 14th and 21st day in all the groups.&#x0D; Conclusion: The encouraging results of our study suggest that the newly formulated mouthwash containing coriandrum Sativum, mint and clove demonstrates anti-inflammatory properties, which may be useful as an adjunctive to mechanical therapy in the prevention and treatment of gingivitis.

Improved cellular immunity and increased insulin in streptozotosin-induced mice using ethanol coriander (Coriandrum sativum) extract

An increase in blood sugar levels is an indication of diabetes mellitus (DM). DM is a metabolic disease characterized by disorders of carbohydrate and fat metabolism due to impaired activity, insulin secretion or both. Alternatively, the body's inability to secrete insulin. The purpose of this study was to determine the effect of coriander extract (Coriandrum sativum) on mice induced by streptozotocin (STZ) on the relative number of CD11b and insulin-IL6 cells. The study used Balb-C strain mice, aged 2.5-3 months, with five (5) treatment groups which were given STZ at a dose of 145mg/kg BW on the 8th day IP (Intraperitoneal) after adaptation for seven days, then add coriander extract with successive doses of 25 (T1), 50 (T2), and 100mg/kg BW (T3), negative control (healthy) (T4) and positive control (STZ) (T5) through the administration of intraperitoneal gastric tube. Blood Glucose is measured on the 13th day. Herbs are given on days 14-28. On the 29th day, the mice. An increase in blood sugar levels is an indication of diabetes mellitus (DM). DM is a metabolic disease characterized by disorders of carbohydrate and fat metabolism due to impaired activity, insulin secretion or both Alternatively, the body's inability to secrete insulin. The purpose of this study was to determine the effect of coriander extract (Coriandrum sativum) on mice induced by streptozotocin (STZ) on the relative number of CD11b and insulin-IL6 cells. The study used Balb-C strain mice, aged 2.5-3 months, with five (5) treatment groups which were given STZ at a dose of 145mg/kg BW on the 8th day IP (Intraperitoneal) after adaptation for seven days, then add coriander extract with successive doses of 25 (T1), 50 (T2), and 100mg/kg BW (T3), negative control (healthy) (T4) and positive control (STZ) (T5) through the administration of intraperitoneal gastric tube. Blood Glucose is measured on the 13th day. Herbs are given on days 14-28. On the 29th day, the mice were sacrificed Furthermore, the pancreas was taken for insulin examination, and the spleen was checked with the relative number of CD11b-IL6 and T CD4 cells using a flow cytometer. Data were quantitatively analyzed using the One Way ANOVA test (p≤0.05). The results showed that doses of coriander in T1 treatment causes an increase in insulin levels, decreased blood sugar levels, weight gain, proliferation and activation of CD4+ T cells, and decrease inflammation (CD11b cell-IL6) on the tissue. This research concludes that extracts of coriander can reduce Hyperglycemia in mice by modulation of cellular immunity and increased levels of insulin

Protective effect of Coriandrum sativum extract against inflammation and apoptosis in liver ischaemia/reperfusion injury.

The aim of this study was to investigate the anti-inflammatory and antioxidant effects of Coriandrum sativum extract on liver ischaemia reperfusion injury at light microscopic and biochemical levels. Sham, ischaemia/reperfusion injury (IRI), IRI + Coriandrum sativum extract and only Coriandrum sativum extract groups were formed. Sixty minutes of ischaemia and 60 minutes of reperfusion were performed. In the treatment group, 300 mg/kg/day Coriandrum sativum was given by gavage. Hepatic tissues were fixed in 4% paraformaldehyde. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and alkaline phosphatase (ALP) enzymes were measured. Nuclear factor-kappa beta (NF-κB), tumour necrosis factor-alpha (TNF-α) and caspase-3 immunohistochemistry staining was performed. Microscopic scoring was performed in terms of sinusoidal congestion, vacuolisation, and necrosis. Sinusoidal enlargement and diffuse congestion, Kupffer cell increase, neutrophil increase in necrotic areas, vacuolisation in hepatocytes, and bile duct proliferation in the portal triad were observed in ischaemia/reperfusion hepatic tissue. Very rare, necrotic areas were observed in the Coriandrum sativum treatment group, while congestion and vacuolisation and bile duct proliferation were decreased compared to the ischaemic group. The AST and ALT levels were increased in the IRI and IRI + Coriandrum sativum groups. When compared to the IRI group, the AST and ALT levels of the Coriandrum sativum were considerably decreased. The IRI and IRI + Coriandrum sativum groups had statistically significant differences in ALP compared to that of the Coriandrum sativum and Sham groups. There was no significant difference between the ALP levels of the IRI and IRI + Coriandrum sativum groups TNF-α, NF-κB and caspase-3 immune positive stained hepatocytes were numerous and widely observed in the injury group. There were positive TNF-α immunohistochemical staining Kupffer cells in the IRI group. In the group treated with Coriandrum sativum, Kupffer cells were not stained, while TNF-α, NF κB and caspase-3 expressing hepatocytes were found to be decreased compared to the IRI group. When the expression values of the TNF-α, NF-κB and caspase-3 groups were evaluated statistically, it was seen that there was a significant decrease in the group treated with Coriandrum sativum. It was found that Coriandrum sativum extract decreased proinflammatory cytokine TNF-α and apoptotic cell death and liver enzymes in liver ischaemia/reperfusion injury.

Anti-cancer inhibition studies of naturally occurring Terpenes using in-vitro technique

Solvent extractions of shade dried seeds of Cyamopsis tetragonoloba, Pithecellobium dulce and Coriandrum sativum plants were executed using organic solvents. The obtained extracted crudes were subjected to the chemical analysis followed by instrumental analysis using standard procedures to identify the naturally occurring phytochemicals [1, 2, 3,]. Limonene, Oleanolic acid and Linalool were obtained from ethanol extracts of Cyamopsistetragonoloba, methanol extract of Pithecellobium dulce and acetone extract of Coriandrumsativum respectively. The compound identification were confirmed by 1H NMR, 13C NMR, IR and Mass spectroscopy [4]. The anti-cancer activity of the extracted terpenes determined using in-vitro analysis on HeLa-Human cervix cell lines. The obtained IC50 value of Oleanolic acid shows better biological activity against HeLa cell lines. It was also found that there is no cell lysis in HeLa cell lines in case of Limonene with concentration less than 30 μg. However, biological activity of Linalool is better in case of HeLa cell line. This suggests that Oleanolic acid and Linalool is good anti-cancer agent as reported from in vitro studies against Hela-Human cervix cell line.

Antischistosomal Activity of Zingiber officinale, Piper nigrum, and Coriandrum sativum Aqueous Plant Extracts on Hamster Infected with Schistosoma mansoni

Schistosomiasis continues to affect the health and quality of life of millions of people around the world. Schistosomiasis has been ranked the second disease after malaria in terms of importance as a targeted tropical disease. Praziquantel (PZQ) is the only drug approved by the World Health Organization (WHO) for the treatment of schistosomiasis. Being the only drug, parasite resistance to this drug has developed. Therefore, the search for new alternatives has been the goal of many researchers. In this study, the effects of aqueous extracts of Zingiber officinale, Piper nigrum, and Coriandrum sativum on Schistosoma mansoni infected golden hamsters (Egyptian strain) were evaluated in vitro and in vivo at different doses of 500, 250, 125, 62.5, and 31.25 μg/ml. In vitro, adult worms of S. mansoni were tested in RPMI-1640 medium for 48 hrs. The results showed that the concentrations 500, 250, and 125 μg/ml of Zingiber officinale and Piper nigrum caused dead of 100% of adult worms within 6 and 12 hrs of incubation, respectively. Although, aqueous extract of Coriandrum sativum at concentrations 500, 250, and 125 μg/ml resulted dead of 100% parasites after 12 to 24 hrs of incubation. In conclusion, Zingiber officinale and Piper nigrum showed efficacy against schistosomiasis in both in vitro and biological experiments of Egyptian schistosome strain, while Coriandrum sativum gave less effective results than the previous ones. Therefore, Zingiber officinale and Piper nigrum may become an innovative treatment for schistosomiasis.

Textiles Functionalized with ZnO Nanoparticles Obtained by Chemical and Green Synthesis Protocols: Evaluation of the Type of Textile and Resistance to UV Radiation

The study evaluates five types of commercial textiles with different cotton and polyester contents widely used in the garment industry. These textile samples have been subjected to treatment by the exhaustion method using zinc oxide nanoparticles (NP ZnO) (textile functionalization) with the aim of improving their efficiency in blocking UV radiation. The ZnO nanoparticles have been obtained by two methods: The green or also called biosynthesis (using the extract of Coriandrum sativum as an organic reducing agent), and the chemical method (using NaOH as an inorganic reducing agent). The results related to the green method show having achieved a defined geometric configuration with an average size of 97.77 nm (SD: 9.53). On the contrary, the nanostructures obtained by the chemical method show pentagonal configurations with average sizes of 113 nm (SD: 6.72). The textiles functionalized with NP ZnO obtained by biosynthesis showed a better efficiency in blocking ultraviolet radiation (UV).

Preliminary study on phytochemical, phenolic content, flavonoids and antioxidant activity of Coriandrum Sativum l. originating in Vietnam

In recent times, advances in the health views of many micronutrients, such as carotenoids, flavonoids, anthocyanins, phenolics, minerals, and molecular-level vitamins have opened a new horizon in the nutrition field. In Vietnam, spice vegetables have long been popularly used in daily meals, increasing the sense of taste of the food as well as taking advantage of the therapeutic properties that are beneficial to their health. Among them, Coriandrum sativum L. is most commonly used because of its attractive aroma and medicinal potential. These vegetable have anti-inflammatory, hypoglycemic, and alleviated gastrointestinal tract problems, and they also show significant cancer-fighting potential. In this research, the leaf extract of Coriandrum sativum L. was tested for preliminary qualitative phytochemical composition, assessing phenolic content by the Folin-Ciocalteu method, flavonoid by aluminum chloride method and activity oxidation resistance (DPPH-2, 2-diphenyl-1-picrylhydrazyl). The results illustrated that the presence of components such as tannins, and saponin. Besides, the total phenolic and flavonoid content were determined as 113.08 mgGAE/g DW and 72.64 mg QE/g DW, respectively. The antioxidant activity obtained with IC50 value were 78.309 ug/ml (DPPH) and 54.489 ug/ml (ABTS). This result shows the effectiveness of Coriandrum sativum L. in increasing antioxidant foods in daily meals.

Innovative application of facile single pot green synthesized CuO and CuO@APTES nanoparticles in nanopriming of Vigna radiata seeds.

Nanopriming is an emerging field of science which uses nanoparticles in solution to improve parameters of seed vigor. This leads to an initial advantage to the crop plant at the germination phase of its life cycle, which is also the most vulnerable phase and may lead to an improved yield. In this study, we have synthesized copper oxide (CuO) and (3-Aminopropyl) triethoxysilane (APTES)-coated CuO (CuO@APTES) nanoparticles via environmentally friendly green synthesis using the extract of Coriandrum sativum (coriander) herb. The synthesized nanoparticles were used as nanoprimers on Vigna radiata (moong bean), a model legume, to promote seed vigor via increase in germination. This was followed by characterization and comparison of both types of nanoparticles using various physicochemical techniques; UV-Visible (UV-Vis), Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), dynamic light scattering (DLS), zeta potential, and transmission electron microscopy (TEM). All characterization techniques pointed out to the successful synthesis and coating of CuO nanoparticles. Seed imbibition and germination assays were performed, which indicated increased imbibition potential and germination promotion at low nanoparticle concentration. Such studies can be used in the development of simple prepackaged nanoprimer products, which can be used by farmers before sowing to provide a boost to their crops and productivity.

Synthesis and Evaluation of Antibacterial Potency of Silver Nanoparticles of Extracts of Ziziphus mauritina and Coriandrum sativum

Synthesis and Evaluation of Antibacterial Potency of Silver Nanoparticles of Extracts of Ziziphus mauritina and Coriandrum sativum

Effect on anxiety of Coriandrum sativum leaf hydroethanolic extract oil and aqueous fraction in swiss albino mice

Background: Anxiety is a protective reflex and the most common disorder. This study was done to evaluate the effect of anxiolytic property of oil and aqueous fractions isolated from hydroethanolic extracts of Coriandrum sativum leaf by novel freezing technique with swiss albino mice.Methods: Hydroethanolic extract of Coriandrum sativum leaves was prepared. Oil and aqueous part were separated with freezing technique. Animals were divided into six groups. Ist group served as control and 1% DMSO was administered orally. IInd to Vth group were administered with Coriandrum sativum oil fraction and Coriandrum sativum aqueous fraction at doses of 400 and 800 mg/kg orally. VIth group was treated with diazepam 1mg/kg orally. After one hour of dosing, battery of test was done viz, elevated plus maze (EPM), light dark arena, photo actometer and rotarod.Results: One-way analysis variance (ANOVA) followed by Dunnett's multiple comparison test was used for statistical analysis. Anxiolytic property was found to be in the following order diazepam&gt;coriandrum sativum aqueous 800&gt;coriandrum sativum aqueous 400&gt;coriandrum sativum oil 800&gt;coriandrum sativum oil 400 mg/kg. All the extracts were devoid of adverse effects of motor coordination.Conclusions: Coriandrum sativum leaf possesses anxiolytic effect. The aqueous fraction of the hydroethanolic extract of the Coriandrum sativum leaf was found to be potent and further analysis may lead to identification of active compounds. The findings that the extract is non-sedating anxiolytic and is of good safety index are promising.

Phytochemical Analysis and Antibacterial Potency against Pathogenic Bacteria of Aqueous and Alcoholic Extract of Ziziphus Mauritiana and Coriandrum Sativum

In present research we had selected two plant-Ziziphus mauritiana commonly known as Indian jujube (Ber) and Coriandrum sativum commonly known as coriander for the phytochemical screening and antimicrobial activity against Kliebsella pneumonia, Clostridium per fringes, Citrobacter freundii and Staphylococcus aureus bacteria. All the bacteria selected in this study are highly pathogenic and drug resistant. Phytochemical screening reveals that both the plants are rich in terms of phytoconstituents and potent against pathogenic bacteria.