Under the background of the slow recovery of the global economy, strengthening regional cooperation is an important driving force to promote the development of the world economy, and has become a trend. In 2013, President Xi put forward the the strategy of "The Belt and Road" (B&R), which not only sought its own development, but also contributed to the development of other countries in line with the historical trend of Chinese wisdom. Over the past five years, the construction of B&R has gradually changed from planning to practice, from vision to reality, and the progress and achievements have exceeded expectations. On the one hand, B&R provides a new opportunity for the development of higher education in China. On the other hand, higher education provides a guarantee for the implementation of B&R. B&R is the latest development concept of China's reform and opening up and foreign policy. Many scholars study the development of higher education from the perspective of B&R. This topic has become a new hot spot of research. In theory, the strategy of B&R originates from the excellent traditional Chinese cultural thought, is a further explanation of China's foreign policy and foreign concept, and is also a further practice of the new concept put forward since the 18th National Congress of the Communist Party of China (CPC). By studying the cooperation mode of higher education between China and the countries along B&R, it is beneficial to increase the international exchange and cooperation in higher education in the future, and to strengthen the cooperation in higher education. To strengthen the cooperation of higher education is beneficial to the great development of the higher education in China, to realize the great rejuvenation of China's dream, to promote the construction of the human destiny community and to create a better future for mankind.