The broadband spectrum contains significantly more information than what the human eye can detect, with different wavelengths providing unique information about the intrinsic properties of an object. Recently, compressive sensing-based strategies for multi-spectral imaging via wavelength filtering at the pixel level on the imaging detector have been proposed for simultaneous acquisition of multi-spectral imaging data greatly reducing the acquisition times. To utilize such compressive sensing strategies for multi-spectral imaging, strong reconstruction algorithms that can reconstruct dense multi-spectral image cubes from the sparse compressively sensed observations are required. This paper proposes a comprehensive inter-spectral multi-layered conditional random field (IS-MCRF) sparse reconstruction framework for multi-spectral compressively sensed data captured using such acquisition strategies. The IS-MCRF framework leverages the information between neighboring spectral bands to better utilize the available information for reconstruction. The proposed framework was evaluated using compressively sensed multi-spectral acquisitions ranging from visible to near infrared spectral bands obtained by a simulated compressive sensing-based multi-spectral imaging system. Results show noticeable improvement over the existing sparse reconstruction techniques for compressive sensing-based multi-spectral imaging systems in preserving spatial and spectral fidelity.
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