Terrestrial ecosystems in China are threatened by land use and future climate change. Understanding the effects of these changes on vegetation and the climate-vegetation interactions is critical for vegetation preservation and mitigation. However, land-use impacts on vegetation are neglected in terrestrial ecosystems exploration, and a deep understanding of land-use impacts on vegetation dynamics is lacking. Additionally, few studies have examined the contribution of vegetation succession to changes in vegetation dynamics. To fill the above gaps in the field, the spatiotemporal distribution of terrestrial ecosystems under the current land use and climate baseline (1970–2000) was examined in this study using the Comprehensive Sequential Classification System (CSCS) model. Moreover, the spatiotemporal variations of ecosystems and their succession under future climate scenarios (the 2030s–2080s) were quantitatively projected and compared. The results demonstrated that under the current situation, vegetation without human disturbance was mainly distributed in high elevation regions and less than 10% of the national area. For future vegetation dynamics, more than 58% of tundra and alpine steppe would shrink. Semidesert would respond to climate change with an expansion of 39.49 × 104 km2, including the succession of the steppe to semidesert. Although some advancement of the temperate forest at the expense of substantial dieback of tundra and alpine steppe is expected to occur, this century would witness a considerable shrinkage of them, especially in RCP8.5, at approximately 55.06 × 104 km2. Overall, a warmer and wetter climate would be conducive to the occurrence and development of the CSCS ecosystems. These results offer new insights on the potential ecosystem response to land use and climate change over the Chinese domain, and on creating targeted policies for effective adaptation to these changes and implementation of ecosystem protection measures.