The conventional bionic compound eye system encounters challenges associated with a complex zoom structure, susceptibility to wear, and elevated costs. In this paper, a preparation method of liquid-filled zoom compound eyes is proposed. A polydimethylsiloxane (PDMS) film is integrated with a microfluidic chamber composed of polymethyl methacrylate (PMMA). The microlens array (MLA, hexagonal array, diameter 800 µm, center distance 850 µm) on the PDMS film is prepared by a wettability-guided dipping method. The sub-eye focal length on zoom compound eyes (ZCEs) is 1.42 mm. By controlling the volume of deionized (DI) water injected into the chamber from 2.41 to 2.71cm3, the focal length of the main lens is adjusted from infinity to 55.51 mm, and the FOV is adjusted from 32° to 58°. This large aperture ZCE combines the advantages of monocular and compound eyes. This method has great potential for advanced micro-optical devices with a wide field of view and tunable imaging capabilities.