Complete Integration Research Articles

THE AUDIT PROCESS OF THE IT SYSTEMS OF A COMPANY THAT PROVIDES ACCOUNTING SERVICES

Over the time, IT systems have constantly evolved and for this reason IT systems must undergo periodic audit procedures to see if they enable the achievement of a company's strategic objectives and the efficient use of IT resources. The main purpose of the paper is to investigate how the audit mission is carried out on IT systems (ERP systems) within a company that provides accounting, consulting, payroll and audit services. The role of these IT systems (ERP systems) is to ensure the correct and complete integration of information within a company. ERP systems provide the perfect maintenance of the internal control system, but also the ability of managers to analyse the information provided by these IT systems as correctly as possible. In this article, the author made a case study, analysing the risks of an IT system of a company that offers accounting services using the MEHARI technique. The results obtained showed that the systems are effective and would withstand cyber-attacks, but could be less resistant in terms of specialized attacks (well-equipped hackers, professional spies).

Factors and Consequences of the Battle between the Seljuks and the Ghaznavids at Dandanqan

Afghanistan, our wonderful country, has a glorious past. Many great men and heroes have been nurtured in this ancient land, leaving valuable contributions in the golden pages of our country's history, which society and the nation take pride in. Among them, we can mention the invaluable services of Sultan Mahmood of Ghaznawi in the political and cultural fields of the country. As soon as he became powerful, he made all possible attempts to broaden his territory. Although the establishment of the independent and grand Ghaznavid state is attributed to Alp-Tegin, its glory is linked to Sabuktigin, especially his son, Sultan Mahmud of Gaznavi. After the fall of the Samani state, Mahmood stepped in, restored the lost state, and founded a vast empire. He worked to strengthen the internal unity of the country by defeating his internal rivals and making comprehensive efforts to implement his various plans. Among his plans and programs was the invasion of India, which he pursued with strong determination and achieved numerous successes. The purpose of this research paper is to examine the factors influencing Sultan Mahmood Ghaznavi's military campaigns in India, his focus on conquests and expansion, the spread of the Islamic religion in non-Islamic lands, and the elevation of religion and the economy during this period. Research has various methods and approaches. This research paper has been prepared with the library research method and by using the most reliable historical books with complete integrity. In conclusion, we can say that Sultan Mahmood Ghaznavi established a central government in India, spread Islamic culture and religion there, and obtained significant economic gains and wealth from the conquest and occupation of India.

Design and Development of Integrated Direct Air Capture and Methanation Processes

AbstractThe synergies from integrating direct air capture and CO2 methanation are assessed and quantified. Three direct air capture and methanation processes with different integration strategies are proposed: only heat integration, direct air capture sorbent regeneration with high‐pressure H2, and complete integration in a single unit. The heat integration study via pinch analysis evaluated the potential energy demand reduction. Overall autothermal operation is achievable, as the heat generated in methanation often exceeds that required for direct air capture sorbent regeneration. A novel process combining CO2 adsorption and methanation in one reactor provided the best productivity and energy demand results. However, this design requires complex cycles and strict demands on the sorbent and catalyst, requiring further development and experimental demonstration.

The Mu2e crystal and SiPM calorimeter

The calorimeter of the Mu2e experiment is being assembled, with all production components completed and tested, apart from the digital electronics that is still underway. The mechanical structure is fully built, with a complete integration and test of all the analog sensors and electronics. We summarize construction and assembly phases, Quality Control tests, calibration procedures and first tests performed in the assembly area, as well as the installation and commissioning plans of the final disks in the Mu2e hall.

Opportunities for the integration of muslim immigrants in European Union countries

The presence of Muslim immigrants in European Union countries has become an undeniable reality, as these immigrants have become an integral part of the demographic composition of EU societies. The strength of these immigrant communities has increased as a result of the intensification of family reunification policies, which have contributed to reshaping and expanding minorities within the European space. Consequently, questions, concerns, and doubts have arisen about the integration of these immigrants into most national communities. These apprehensions are primarily based on the legal mechanisms required to integrate these minorities into the nation-state, which is founded on citizenship rights in Europe, and on the practical measures that guarantee their integration in an appropriate form and content. On this basis, the adopted integration policies that attempt to reposition Muslims in Europe at the economic, social, and, to some extent, cultural levels raise many concerns about their ability to integrate these Muslim immigrants and about the possible opportunities for their proper integration in light of their cultural, religious, and social specificities. Through this paper, researchers attempt to examine the opportunities for these Muslim immigrants to integrate, considering the legal complexities and social problems they face, which hinder their complete integration into these societies.

A Tomato Recognition and Rapid Sorting System Based on Improved YOLOv10

In order to address the issue of time-consuming, labor-intensive traditional industrial tomato sorting, this paper proposes a high-precision tomato recognition strategy and fast automatic grasping system. Firstly, the Swin Transformer module is integrated into YOLOv10 to reduce the resolution of each layer by half and double the number of channels, improving recognition accuracy. Then, the Simple Attention Module (SimAM) and the Efficient Multi-Scale Attention (EMA) attention mechanisms are added to achieve complete integration of features, and the Bi-level Routing Attention (BiFormer) is introduced for dynamic sparse attention and resource allocation. Finally, a lightweight detection head is added to YOLOv10 to improve the accuracy of tiny target detection. To complement the recognition system, a single-vertex and multi-crease (SVMC) origami soft gripper is employed for rapid adaptive grasping of identified objects through bistable deformation. This innovative system enables quick and accurate tomato grasping post-identification, showcasing significant potential for application in fruit and vegetable sorting operations.

The Application of Large Language Models in Gastroenterology: A Review of the Literature.

Large language models (LLMs) are transforming the medical landscape by enhancing access to information, diagnostics, treatment customization, and medical education, especially in areas like Gastroenterology. LLMs utilize extensive medical data to improve decision-making, leading to better patient outcomes and personalized medicine. These models are instrumental in interpreting medical literature and synthesizing patient data, facilitating real-time knowledge for physicians and supporting educational pursuits in medicine. Despite their potential, the complete integration of LLMs in real-life remains ongoing, particularly requiring further study and regulation. This review highlights the existing evidence supporting LLMs' use in Gastroenterology, addressing both their potential and limitations. Recent studies demonstrate LLMs' ability to answer questions from physicians and patients accurately. Specific applications in this field, such as colonoscopy, screening for colorectal cancer, and hepatobiliary and inflammatory bowel diseases, underscore LLMs' promise in improving the communication and understanding of complex medical scenarios. Moreover, the review discusses LLMs' efficacy in clinical contexts, providing guideline-based recommendations and supporting decision-making processes. Despite these advancements, challenges such as data completeness, reference suitability, variability in response accuracy, dependency on input phrasing, and a lack of patient-generated questions underscore limitations in reproducibility and generalizability. The effective integration of LLMs into medical practice demands refinement tailored to specific medical contexts and guidelines. Overall, while LLMs hold significant potential in transforming medical practice, ongoing development and contextual training are essential to fully realize their benefits.

Non-vascularized coracoid process autograft for glenoid reconstruction in revision shoulder arthroplasty.

To report the radiological and clinical outcomes of non-vascularized coracoid process autografts used for glenoid reconstruction during revision shoulder arthroplasty. This is a retrospective, monocentric study from January 2016 to October 2022 targeting patients treated with a coracoid bone graft for glenoid reconstruction during revision of shoulder arthroplasty. The primary outcome measures were coracoid graft union rate and graft-implant osseointegration. Secondary outcome measures included clinical and CT-scan identified radiological complications and functional outcomes as measured by the Visual Analog Scale (VAS), Range of Motion (ROM), Subjective Shoulder Value (SSV), Constant score (absolute and ponderate), and ASES score. Fifteen patients (9 males, 6 females; mean age 66.9years, range 38-85) were included. At a mean follow-up of 20.9months (range 12-56months), 93.3% achieved complete graft integration. One case of partial lysis without baseplate loosening was noted. Regarding range of motion, the mean forward elevation was 130° (range 90°-170°), external rotation at the side 25° (range 10°-40°), external rotation in 90° of abduction 45° (range 10°-80°), and internal rotation 52° (range 10-80°). The mean VAS for pain was 1.1 (range 0-8), mean SSV 67.3% (range 40-90%), mean ASES score 85.5 (range 65-98.3), mean Absolute Constant score 58.6 (range 21-83), and mean Ponderate Constant score 77.5% (range 28.8-110.7%). No neurological injuries were reported. Utilizing a non-vascularized coracoid graft during shoulder arthroplasty revision is a safe, reproducible, and time-efficient technique that demonstrated satisfactory osseointegration, implant stability, good functional results, and a low complication rate.

On the magnetostatic scalar potential and magnetic field of a cylindrical magnet

Abstract The magnetostatic potential and magnetic field of a solid and hollow cylindrical magnet is calculated everywhere in space in terms of complete elliptic integrals. These expressions are calculated using an electromagnetic analogy with the electrostatic potential and electric field of two uniformly charged disks with opposite surface density. The analogy is employed to study intuitively the discontinuities and the dipolar approximation of the fields $\vec{H}$ and $\vec{B}$. The range of validity of the dipolar approximation has been studied along the cylinder axis and in the midplane perpendicular to the cylinder axis, comparing them with the obtained general expression.

The Magnetic Anomaly Map of Paraná State: An Integration of Airborne Surveys Performed Over the Years

Over the last decades, several aerial survey campaigns have been conducted in the State of Paraná. However, we did not have a complete magnetic data integration and analysis focused on the Paraná’s geological context. Therefore, the main objective of this work is to provide the integration of all available data and realize a general analysis to make the Integrated Magnetic Map of the Paraná State, in collaboration with the Geological Survey of Brazil (SGB-CPRM). After integrate the data we have applied processing techniques on public airborne magnetic data, available from the Geological Survey of Brazil database (GeoSGB). For this integration, it was used the minimum curvature interpolation, with cell sizes according to each survey. All gridded data was extrapolated upward from the original height to the altitude of 1800 m. Afterwards, we applied the upward continuation for 2700 m and the following filters: vertical gradient (VDR), total horizontal derivative (THDR), analytic signal (AS), or tilt derivative (TDR), tilt angle of the horizontal derivative (TAHG) and vertical integral of the analytic signal (VIAS). The final results provide valuable maps (and grids) that can be used by the community for future works. In this work we tried to do a simple overview of the structural framework of Paraná State, representing the main magnetic structures of the Paraná State basement and compare them with the most important structures already mapped in surface over the years. All the data present in this work and other filters tests are available and can be access in the supplementary material (https://acervodigital.ufpr.br/ https://hdl.handle.net/1884/89075 and also at zenodo repository https://doi.org/10.5281/zenodo.12820642).

Optimal power-type Heronian and Lehmer means inequalities for the complete elliptic integrals

In this paper, we prove that the inequalities H p ( K ( r ) , E ( r ) ) < π 2 , L q ( K ( r ) , E ( r ) ) < π 2 hold for all r ∈ ( 0 , 1 ) if and only if p ≤ − log ⁡ 3 / log ⁡ ( π / 2 ) and q<−1, where H p ( a , b ) and L q ( a , b ) are respectively the p-th power-type Heronian mean and q-th Lehmer mean of a and b, and K ( r ) and E ( r ) are respectively the complete elliptic integrals of the first and second kinds.

Exact closed-form solution for the completely integrable helmholtz-duffing oscillator with applications to real-world problems

The Helmholtz-Duffing oscillator is an important vibration model that can be used to study many engineering systems and physical phenomena. In this article, we derived new exact closed-form solutions for the completely integrable Helmholtz Duffing oscillator subject to a constant force. The exact solution was derived naturally from the first integral of the governing differential equation. This approach is completely different from the ansatz method, used in previously published studies, where the exact solution was forced to take the form an initially assumed solution. Through various algebraic transformations and with the aid of standard elliptic integral tables, the present exact period was derived in terms of the complete elliptic integral of the first kind while the exact displacement was derived in terms of the Jacobi cosine function. Unlike the exact ansatz solutions, which have limited range of validity, the present exact solutions are applicable to all bounded periodic states of the Helmholtz-Duffing oscillator with constant force. The validity of the present exact solutions was verified using numerical solutions and published exact solutions in the form of the Weierstrass elliptic function. It was found that the numerical differentiation method produced significant errors for some system inputs and cannot be relied on as a benchmark solution. However, the present exact solutions are benchmark solutions that could be used to check the accuracy of new and existing approximate solutions. Finally, the application of the exact solutions to analyze some real-world problems was demonstrated.

Long-Term Survival and Regeneration Following Transplantation of 3D-Printed Biodegradable PCL Tracheal Grafts in Large-Scale Porcine Models.

Polycaprolactone (PCL) implants in large animals show great promise for tracheal transplantation. However, the longest survival time achieved to date is only about three weeks. To meet clinical application standards, it is essential to extend the survival time and ensure the complete integration and functionality of the implant. Our study investigates the use of three-dimensional (3D)-printed, biodegradable, PCL-based tracheal grafts for large-scale porcine tracheal transplantation, assessing the feasibility and early structural integrity crucial for long-term survival experiments. A biodegradable PCL tracheal graft was fabricated using a BIOX bioprinter and transplanted into large-scale porcine models. The grafts, measuring 20 × 20 × 1.5 mm, were implanted following a 2 cm circumferential resection of the porcine trachea. The experiment design was traditionally implanted in eight porcines to replace four-ring tracheal segments, only two of which survived more than three months. Data were collected on the graft construction and clinical outcomes. The 3D-printed biosynthetic grafts replicated the native organ with high fidelity. The implantations were successful, without immediate complications. At two weeks, bronchoscopy revealed significant granulation tissue around the anastomosis, which was managed with laser ablation. The presence of neocartilage, neoglands, and partial epithelialization near the anastomosis was verified in the final pathology findings. Our study demonstrates in situ regenerative tissue growth with intact cartilage following transplantation, marked by neotissue formation on the graft's exterior. The 90-day survival milestone was achieved due to innovative surgical strategies, reinforced with strap muscle attached to the distal trachea. Further improvements in graft design and granulation tissue management are essential to optimize outcomes.

Fields of Interdisciplinarity

This paper provides an empirical account of the problem of interdisciplinarity in the field sciences, considering it as a driver of ontological change. Our case study is an ongoing interdisciplinary research project in environmental science. Its objective is to trace the long-term histories of European old-growth forests. To account for the mechanisms involved when researchers seek to do interdisciplinary science in the field, we describe 1/ four research practices that take advantage of the spatial order of the study site in order to make forests temporal processes knowable, thereby producing a field site crisscrossed by multiple spatiotemporal orders; 2/ those practices geared towards articulating these spatiotemporal orders and the limits faced by the consortium towards their complete integration; 3/ how such articulation transforms the conception of old-growth forests as spaces shaped by historical processes integrating human activities and valued ecological processes. We argue that interdisciplinary research practice in environmental field sciences does not lead to a synthesis of pre-existing domains of knowledge production. Rather, it does tend to transform both the object of study and the disciplines involved. The field, as both an object of study and a research place, becomes a broker toward ontological changes.

Synthesis composit electrospun based gum-resin/polycaprolactone fibers for biomedical application

Electrospun fibers for tissue engineering have recently seen significant advancements. In this study, we created composite fibers by combining Pistacia atlantica Gum-Resin and Poly(ε-caprolactone) (PCL) polymer using the electrospinning method. We examined the morphology, biodegradability, thermal stability, and hydrophilicity of the prepared scaffolds using Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), thermogravimetric (TG) differential scanning calorimetry (DSC), and water contact angle measurements. The results indicated complete integration between the materials and successful synthesis of fibers through the electrospinning method. SEM images demonstrated bead-free fibers with different blending ratios of Gum-Resin and PCL. Fibers with a diameter of 100–200 nm and 1–7 μm were obtained with a 9:1 blending ratio of PCL to Gum-Resin. Additionally, PCL/Gum-Resin fibers with an 8:2 blending ratio exhibited an interwoven and porous fiber network structure with a 1–7 μm fiber diameter. The water contact angle measurements revealed the hydrophilic surface of the fibers, with a WCA of 61.2°. Thermogravimetric (TG) and differential scanning calorimetric (DSC) analysis showed a melting peak at approximately 57°. Cell culture results indicated good cytocompatibility of the fibers. The scaffold sample exhibited inhibitory activity against S. aureus (22 ± 0.26 mm) and E. coli (16.8 ± 0.15 mm) bacteria. These findings suggest that the fabricated fibers could serve as an effective scaffold for wound healing.

Examining challenges and strategies in implementing STEM education in Malaysian secondary schools: perspectives of teachers and students

This study examines the obstacles hindering the complete integration of STEM education in secondary schools, considering perspectives from both teachers and students, and proposing effective strategies. Employing a quantitative survey approach, the research involves 30 STEM teachers and 70 secondary school students. Findings demonstrate a consensus among participants, emphasizing issues such as inadequate teaching equipment and facilities as significant barriers to comprehensive STEM implementation. Educators favor technology-integrated teaching methods, while students show enthusiasm for incorporating these tools into their learning. Proposed effective strategies include enhancing internet accessibility and infrastructure. The study underscores the importance of engaging diverse stakeholders—teachers, parents, societal actors, and governmental bodies—to fully understand challenges and promote successful STEM integration in secondary education.

NeVer2: learning and verification of neural networks

AbstractNeVer2 is an open-source, cross-platform tool aimed at designing, training, and verifying neural networks. It seamlessly integrates popular learning libraries with our verification backend, offering their functionalities via a graphical interface. Users can design the structure of a neural network by intuitively arranging blocks on a canvas. Subsequently, network training involves specifying dataset sources and hyperparameters through dialog boxes. After training, the verification process entails two steps: (i) incorporating input preconditions and output postconditions via dedicated blocks, and (ii) initiating verification with a simple “push-button” action. To our knowledge, there is currently no other publicly available tool that encompasses all these features. In this paper, we present a comprehensive description of NeVer2, illustrating its complete integration of design, training, and verification through examples. Additionally, we conduct experimental analyses on various verification benchmarks to illustrate the trade-off between completeness and computability using different algorithms. We also include a comparison with state-of-the-art tools such as $$\alpha $$ α ,$$\beta $$ β -CROWN and NNV for reference.

The cell membrane as biofunctional material for accelerated bone repair

The cell (plasma) membrane is enriched with numerous receptors, ligands, enzymes, and phospholipids that play important roles in cell-cell and cell-extracellular matrix interactions governing, for instance, tissue development and repair. We previously showed that plasma membrane nanofragments (PMNFs) act as nucleation sites for bone formation in vivo, and induce in vitro mineralization within 1 day. In this study, we optimized the methods for generating, isolating, and applying PMNFs as a cell-free therapeutic to expedite bone defect repair. The PMNFs were isolated from different mouse cell lines (chondrocytes, osteoblasts, and fibroblasts), pre-conditioned, lyophilized, and subsequently transplanted into 2 mm critical-sized calvarial defects in mice (n = 75). The PMNFs from chondrocytes, following a 3-day pre-incubation, significantly accelerated bone repair within 2 weeks, through a coordinated attraction of macrophages, endothelial cells, and osteoblasts to the healing site. In vitro experiments confirmed that PMNFs enhanced cell adhesion. Comparison of the PMNF efficacy with phosphatidylserine, amorphous calcium phosphate (ACP), and living cells confirmed the unique ability of PMNFs to promote accelerated bone repair. Importantly, PMNFs promoted nearly complete integration of the regenerated bone with native tissue after 6 weeks (% non-integrated bone area = 15.02), contrasting with the partial integration (% non-integrated bone area = 56.10; p < 0.01, Student's test) with transplantation of ACP. Vickers microhardness tests demonstrated that the regenerated bone after 6 weeks (30.10 ± 1.75) exhibited hardness similar to native bone (31.07 ± 2.46). In conclusion, this is the first study to demonstrate that cell membrane can be a promising cell-free material with multifaceted biofunctional properties that promote accelerated bone repair. Statement of significance•For the first time, the cell (plasma) membrane is used as material for bone repair.•The plasma membrane from chondrocytes promoted rapid bone repair within 2 weeks, with complete integration of the newly formed bone with the surrounding native tissue.•The plasma membrane from chondrocytes presented multifaceted effects, strongly promoting the attraction of macrophages, endothelial cells and osteoblasts to the healing site.

Photoacoustic imaging for three-dimensional bioprinted constructs

Bioimaging is used to inspect the successful growth and functional differentiation of cells in printed biomaterials, which are ultimately finalized into functional artificial tissues capable of replacing native tissues. While optical bioimaging techniques are commonly utilized, the current trend in three-dimensional (3D) bioprinting towards replicating complex 3D microarchitectures poses a challenge for conventional optical imaging techniques in providing clear cross-sectional images due to the opaque nature of tissue. Consequently, these limitations necessitate lengthy and destructive preparation processes, which are associated with sacrificing cell viability and damaging the bioprinted material. Photoacoustic imaging (PAI) is a versatile imaging technique that extends the advantages of the optical bioimaging technique to undiscovered depths enabled by its acoustic hybridity, making itself a promising tool for non-destructive imaging of 3D bioprinted constructs. In this review, we introduce the flexible spectral contrasts provided by PAI, which are potentially applicable to 3D-bioprinted constructs, and summarize bioprinting studies that functionally implement PAI for in vitro and in vivo assessments. Finally, we provide an outlook on practical considerations for the more complete integration of these two fields, anticipating more fruitful discoveries as bioprinting advances towards more complex hierarchies.

A new era of synthetic biology-microbial community design.

Synthetic biology conceptualizes biological complexity as a network of biological parts, devices, and systems with predetermined functionalities and has had a revolutionary impact on fundamental and applied research. With the unprecedented ability to synthesize and transfer any DNA and RNA across organisms, the scope of synthetic biology is expanding and being recreated in previously unimaginable ways. The field has matured to a level where highly complex networks, such as artificial communities of synthetic organisms, can be constructed. In parallel, computational biology became an integral part of biological studies, with computational models aiding the unravelling of the escalating complexity and emerging properties of biological phenomena. However, there is still a vast untapped potential for the complete integration of modelling into the synthetic design process, presenting exciting opportunities for scientific advancements. Here, we first highlight the most recent advances in computer-aided design of microbial communities. Next, we propose that such a design can benefit from an organism-free modular modelling approach that places its emphasis on modules of organismal function towards the design of multispecies communities. We argue for a shift in perspective from single organism-centred approaches to emphasizing the functional contributions of organisms within the community. By assembling synthetic biological systems using modular computational models with mathematical descriptions of parts and circuits, we can tailor organisms to fulfil specific functional roles within the community. This approach aligns with synthetic biology strategies and presents exciting possibilities for the design of artificial communities. Graphical Abstract.