We investigate the uncertainty in the strong coupling alpha _S(M_{Z}^{2}) when allowing it to be a free parameter in the recent MMHT global analyses of deep-inelastic and related hard scattering data that was undertaken to determine the parton distribution functions (PDFs) of the proton. The analysis uses the standard framework of leading twist fixed-order collinear factorisation in the {overline{mathrm{MS}}} scheme. We study the constraints on alpha _S(M_{Z}^{2}) coming from individual data sets by repeating the NNLO and NLO fits spanning the range 0.108 to 0.128 in units of 0.001, making all PDFs sets available. The inclusion of the cross section for inclusive tbar{t} production allows us to explore the correlation between the mass m_t of the top quark and alpha _S(M_{Z}^{2}). We find that the best-fit values are alpha _S(M_{Z}^{2})=0.1201pm 0.0015 and 0.1172pm 0.0013 at NLO and NNLO, respectively, with the central values changing to alpha _S(M_Z^2)=0.1195 and 0.1178 when the world average of alpha _S(M_{Z}^{2}) is used as a data point. We investigate the interplay between the uncertainties on alpha _S(M_{Z}^{2}) and on the PDFs. In particular we calculate the cross sections for key processes at the LHC and show how the uncertainties from the PDFs and from alpha _S(M_{Z}^{2}) can be provided independently and be combined.
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