AbstractCoal burst is a serious hazard in deep coal mining. To investigate the coal burst proneness evolution during multiple mining disturbances (MMD), this paper implemented a range of uniaxial cyclic loading–unloading tests coupled with acoustic emission (AE) measurement to simulate the loading–unloading effects of the MMD. The maximum load was used to simulate the highest load that the coal has endured in history, the loading–unloading rate was used to simulate the mining speed, and the loading–unloading cycles were used to simulate the number of mining disturbances. Finally, the burst proneness indexes of the damaged coal sample are measured and compared with the origin coal sample. Analysis on the experiment results suggest that, the burst proneness increases when the maximum load is 30% of the uniaxial compressive strength (UCS), interestingly, when the low loading–unloading rate is applied, 50% of the UCS enlarge the burst proneness as well. However, it decreases when the maximum load is 70% of the UCS. Sensitivity analysis indicates that the maximum load, loading–unloading rate, and loading–unloading cycles exhibit decreasing influence sensitivity to the elastic modulus, as well as to the UCS and duration of dynamic fracture. Similarly, the influence sensitivity of maximum load, loading–unloading cycles, and loading–unloading rate to the elastic strain energy index decreases, as well as to the bursting energy index. To ensure the safety of coal mining, it is crucial to avoid the disturbances that would put the coal under low loading and low loading rate.