EEG signals are valuable signals in clinical medicine, brain research, and the study of neurological illnesses. However, EEG signal attenuation may occur at any time from signal generation through BCI device acquisition due to defects in the brain–computer interface (BCI) devices, restrictions in the dynamic network, and individual variations across the subjects. The attenuation of EEG data will alter the data distribution and lead to information fuzziness, substantially influencing subsequent EEG research. A model based on one-dimensional residual convolutional neural networks (1D-ResCNN) and transfer learning is proposed in this article to reduce the negative impacts of EEG attenuation. An end-to-end manner maps an attenuated EEG signal to a normal EEG signal. The structure employs a multi-level residual connection structure with varying weight coefficients, transferring characteristics from the bottom to the top of the convolutional neural network, enhancing feature learning. In addition, we initialize the subsequent denoising model using the transfer learning method. The combination of these two networks can well solve the attenuation problem of EEG signals. Experiments are carried out using the EEG-denoisenet data set. According to the findings, the model can yield a clear waveform with a decent SNR and RRMSE value.