Throughout their careers, athletes frequently struggle with pain and inflammation, which frequently reduces performance and slows recovery. The use of analgesics in sports medicine is examined here, with a focus on how athletes might manage their pain and inflammation. In the opening section of the chapter, a general overview of pain and inflammation in relation to sports injuries is given, emphasizing the negative consequences these conditions have on athletic performance. We explored the numerous analgesics used in sports medicine, such as acetaminophen, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and local anesthetics. The mode of action, indications, advantages, drawbacks, and potential side effects of each analgesic class are examined, highlighting the importance of comprehending how each affects the well-being and performance of athletes. The article also explored the effects of analgesics on athletic performance, outlining both the advantages of temporary pain relief and potential drawbacks such as hiding underlying problems or encouraging dependency. It is highlighted how crucial it is for athletes to have individualized pain management programs, as the fine line between pain management and injury aggravation is discussed. In addition, ethical issues surrounding the use of analgesics in sports, such as doping laws, fair play, and possible analgesic abuse for the purpose of enhancing performance, are discussed. To maintain the integrity of sports and safeguard athletes' wellbeing, the responsible use of and adherence to rules are strongly encouraged. This review examines integrative treatments in sports medicine, such as physical therapy, mind-body interventions, and nutritional interventions, which provide effective alternatives for managing pain and inflammation without relying primarily on analgesics in light of alternative approaches. Examples of analgesic use in sports medicine are highlighted in real-world case studies, highlighting how it affects players' careers and well-being. The review's conclusion looks at potential long-term consequences for athletes' health as well as future directions.