Concentrated Chloride Solutions Research Articles

Development of a non-equimolar AlCrCuFeNi high-entropy alloy and its corrosive response to marine environment under different temperatures and chloride concentrations

This work aims to characterize the influence of temperature and chloride solution concentration on the corrosion behavior of a newly developed high-entropy alloy system (Al2Cr5Cu5Fe53Ni35) in a simulated marine environment. A direct correlation was found between temperature and chloride concentration with localized corrosion resistance. The Point Defect Model approach is employed to analyze the influence of the temperature and chloride concentration upon the properties of the passive film formation over the alloy surface in seawater solutions. It turns out that the present system alloy exhibits a better local corrosion resistance than conventional martensitic stainless steel UNS S40300 when temperature is below 60 ∘C in similar electrolytic environment.

Analysis of a novel double-effect split mechanical vapor recompression systems for wastewater concentration

A novel double-effect split mechanical vapor recompression (MVR) system is proposed in this paper to reduce the system operation cost together with the technical requirements for the steam compressor. Theoretical models of the novel double-effect split MVR system together with the double-stage MVR system and double-effect downstream MVR system are established by the simulation software of Aspen Plus. Performances of the three systems for the concentration of calcium chloride solution with a mass flow rate of 1000 kg/h are simulated. For a better evaluation, analysis of the energy consumption, operation cost, compressor operating parameters and gained output ratio are carried out with the simulation results. It is concluded that an optimal steam ratio exists for the smallest compressor power consumption of the double-effect split MVR system which is 0.3 for the simulated conditions. The operation cost beneficial of the novel system increases with the rise of electricity price and final mass fraction of the solute. The maximal suction volume flow and pressure ratio of the steam compressor in the novel system are both the smallest among the three MVR systems. The pressure ratio ranges from 1.2 to 1.7 which can be easily realized by mature roots compressor or centrifugal compressor. Exergy efficiency of the novel system is also the highest. Development and application of heat pump or solar energy fresh steam generator can further enhance advantages of the novel system.

Physicochemical parameters of a hydrochemical technology employing sodium chloride to obtain cryolite used in aluminium production

The paper aims to study the physicochemical parameters of a hydrochemical technology employing hydrofluoric acid and local mineral resources (sodium chloride) to obtain cryolite used in the electrolysis of cryolite-alumina melts. In order to determine the elemental chemical and phase compositions of initial, intermediate, and final products, titration and X-ray diffraction analysis (using an upgraded Dron-2 unit) were employed. The conducted studies indicate that the proposed process of cryolite production from hydrofluoric acid at 28–30 % concentration using aluminium hydroxide and a concentrated sodium chloride solution occurs at 25 °С for 10–15 min. The yield of cryolite reaches 87.6 %, while ~12 % of cryolite remains dissolved in the hydrochloric acid solution. With the temperature rising from 25°С to 95°С, the cryolite yield is shown to decrease from 87.6 % to 69.3 % due to its higher solubility in the formed hydrochloric acid. The cryolite production process was validated via X-ray diffraction analysis. The analysed sample was found to be consistent with the cryolite reference, i. e., indicating an interaction between sodium chloride and fluoroaluminic acid. The conducted studies served as a basis for developing a process flow diagram of hydrochemical cryolite production using hydrofluoric acid, aluminium hydroxide, and sodium chloride. The conducted studies revealed that the technology of cryolite production employing sodium chloride is easy to implement and cost-effective due to the use of local mineral resources and low energy consumption.

Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan – PLGA platform

This study is a continuation of a previous study in which two model drugs, sodium salicylate (highly water-soluble) and indomethacin (low water-soluble) were loaded into an erodible hydrogel, made of ionically crosslinked chitosan (x-Ct). The erosion rate of the x-Ct matrix was controlled by its immersion in calcium chloride solutions (de-crosslinker) of different concentrations, leading to synchronization of the release rates of the two drugs over 2 h. In the present study, a modified platform was developed in order to (a) synchronize the release rates of the two cytotoxic drugs, topotecan (TT, highly water soluble) and paclitaxel (PTX, poorly water soluble); (b) prolong the erosion duration and the derived concomitant release of the two drugs to several days. TT was loaded into a PLGA sphere, which was co-loaded with calcium chloride (CaCl2). The sphere was then placed in an aqueous solution of chitosan (Ct) in which PTX was dispersed. A PLGA core-containing hydrogel was then produced by ionically crosslinking the Ct. The formulation screening section of the study includes a statistically designed Fractional Factorial experiment. It was comprised of the following five experimental factors: (a) the type of Ct and (b) its relative amount in the formulation, (c) the type of ionic crosslinker (citric acid or oxalic acid), (d) the concentration of the ionic crosslinker and (e) the co-loaded amounts of CaCl2 (the constitutional de-crosslinking agent). The difference factor, f1, and the similarity factor, f2, of the TT and PTX release profiles into water, were used as the experimental responses. The computerized prediction models were employed to assess the collective effects of the pre-determined experimental factors on the difference factor, f1, and the similarity factor, f2 (the response factors), by employing a fractional factorial design and multifactorial analysis, without the need to account for the exact mechanisms of the release processes involved. The final composite platform was capable of releasing TT and PTX, at similar (concomitant) rates, over a period of 7 days, a finding which suggests that the novel polymeric platform may serve as a multi-drug implant. An attractive medical application for such a device would be post-operative local treatment that could benefit from localized combination chemotherapy after the removal of malignant tissues, in the surgical treatment of breast cancer, ovarian cancer, glioma and peritoneal carcinomatosis.

Experimental Study on Damage Characteristics of Solidified Mud under Coupling Action of Freeze-Thaw Cycle and Chloride Salt

The physical properties of solidified mud will deteriorate under the combined action of freezing-thawing cycle and chlorine salt, which will affect the safety and stability of solidified mud engineering. In order to study the damage characteristics of solidified mud under the action of freeze-thaw cycle and chloride salt, the solidified mud samples were soaked in different concentrations of sodium chloride solution and treated with freeze-thaw cycle. Besides, the unconfined compressive strength test was carried out to study the damage characteristics of the samples caused by different concentrations of sodium chloride solution and freeze-thaw cycles. The test results show the following. (1) Under the action of freeze-thaw cycle and sodium chloride solution, the surface of the sample deteriorated in varying degrees. With the increase in freeze-thaw cycle times and sodium chloride solution concentration, the mass loss of the sample was greater. (2) Under the action of chlorine salt and freeze-thaw cycle, the strength of the sample decreases with the increase in freeze-thaw cycle times. With the increase in the concentration of sodium chloride solution, the strength of the sample decreases and the damage degree increases gradually. (3) Under the action of freeze-thaw cycle, the internal pores of the samples gradually expand and more honeycomb holes appear, and the content of hydration products is higher. As the concentration of sodium chloride solution increases, the particle connection inside the sample gradually weakens, and the sample is more likely to be damaged.

Influences of zinc chloride on fast pyrolysis of pinewood

Fast pyrolysis is a thermochemical process which converts biomass into intermediate bio-oil and biochar products, which can be further processed to produce end products. Bio-oil is an organic liquid containing myriads of organic chemicals derived from the decomposition of cellulose, hemicellulose, and lignin components in lignocellulosic biomass. There are chemicals in bio-oil which are highly valuable as specialty chemicals, such as furfural, levoglucosan and levoglucosenone. Unfortunately, the amounts of these chemicals are typically too small, which makes it uneconomical to extract them from bio-oil. This work is focused on fast pyrolysis of pinewood, a well-known softwood used in paper industry. In this work, it was demonstrated that bio-oil containing higher fractions of furfural and levoguclosenone can be produced by treating pinewood feedstock with zinc chloride prior to pyrolysis. The batch pyrolysis studies by using a micropyrolyzer, a batch tubular reactor, and a thermogravimetric analyzer showed that the amounts of zinc chloride impregnated to pinewood feedstock significantly affect the yields of bio-oil and biochar products and the composition of chemicals in bio-oil. Increasing the concentration of zinc chloride solution used for pretreating the feedstock resulted in higher yields of biochar containing higher amount of the salt. Optimum concentrations of furfural and the two sugars in bio-oil product seemed to be obtained from pyrolysis of pinewood that was pretreated with 5wt% zinc chloride solution. Pretreatment with higher salt concentration reduced the concentration of levoglucosan but did not affect the other two valuable chemicals.

Research on Resistance to Sulfate and Chloride of Reinforced Metakaolin-Based Geopolymers

This research aims to examine the sulfate and chloride durability behaviors of geopolymer composites synthesized by the alkali activation of metakaolin (MK), reinforced by boron waste colemanite (C), silica fume (SF), and slag (S). The resultant geopolymer composites were subjected to magnesium sulfate (MgSO4) solution (concentration 10%), sodium sulfate (Na2SO4) solution (concentration 10%), and sodium chloride (NaCl) solution (concentration 10%) for up to 12 months. The compressive and flexural strengths, microstructure (X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM)), weight changes, and visual inspection of the geopolymer composites were investigated to evaluate their durability behavior. The conclusion proved that the mix of a metakaolin with the addition of 10% C, and 20% SF shows the highest compressive strength for the studied range of mixture design. In geopolymer mortar samples, compressive strength increase was observed due to sodium chloride and sodium and magnesium sulfate effects after three months, while a decrease was observed after six months. These fluctuations were due to the diffusion of solutions in the matrix, formed during the transition of alkali ions from the samples to the solution. The loss of strength after three months could be due to the presence of microcracks, as a consequence of ettringite and gypsum creation in the pores, as well as the transition of alkalis from the sample matrix to the solution.

Chloride – induced delayed ettringite formation in Portland cement mortars

The present paper reports an obscure new phenomenon herein referred to as chloride – induced delayed ettringite formation (CLIDEF). In the study, mortar mixtures of proportions 1:2.25:0.47 cement to sand to water, were used to prepare 25 × 25 × 285 mm prisms. Incorporated into Portland cement CEM I 42.5R were varied sulphate levels of 2%, 3%, 4%, 5%, 7% and 8% total SO3 content. The prisms were cast and heat – cured at 95 °C then stored in chloride solutions of varied concentrations comprising 0, 0.25, 0.50, 0.75, 1.00, 1.50, 2.00, 3.0 M NaCl. Expansion values of the prisms were monitored for ages of up to 180 weeks.It was found that pessimum expansion occurred at 0.25 to 1.0 M NaCl concentrations. Cementitious systems that were non – expansive under storage in water became expansive upon storage in NaCl solutions of the optimum concentration range 0.25 to 1.0 M NaCl, giving rise to CLIDEF.

Microwave irradiation spectrum of graphene oxide paper regulated by Na ions

In this paper, we found that the presence of sodium chloride (NaCl) can effectively inhibit the diffusion of graphene oxide (GO) in water. Based on this discovery, we reported a simple preparation method of GO paper regulated by Na ions. By adjusting the drying temperature and the mass fraction of NaCl solution, the preparation and complete stripping of GO paper can be easily completed, thereby obtaining free-standing GO paper. Further, we also found that the introduction of sodium ions would cause changes in the microwave irradiation spectrum of GO paper, and the change was related to the mass fraction of NaCl solution used, which could be used to detect sodium ions and the concentration of NaCl solution. Besides, our study also showed that MWRGO paper with NaCl solution treatment can more effectively remove methylene blue in water, compared with MWRGO paper without NaCl solution treatment. This study provides the possibility of the preparation of GO paper based on seawater and also provides a new method for the detection of sodium ions and determination of sodium chloride solution concentration. It has important application prospects in the preparation of GO paper, sensor and water treatment.

Contribution of Diffusing Hydrogen to Anodic Processes and Pitting for Iron in Chloride-Bearing Bicarbonate Solutions

The effects of diffusing hydrogen atoms on anodic processes and pitting corrosion for iron in chloride-bearing bicarbonate solutions were studied with a dual cell for realizing the hydrogen diffusing and electrochemical measurements simultaneously. A high concentration of chloride in solution, precleaning, and diffusing hydrogen in iron can move the open-circuit state from a passive state to an active dissolution state. Potentodynamic anodic polarization curves show that the effect of diffusing hydrogen is strongly dependent on the chloride concentration in the solution. The diffusing hydrogen atoms enhance the anodic reaction before the oxygen evolution potential when the chloride concentration is low while they enhance the anodic reaction in the overall potential range when the chloride concentration is high. In addition, diffusing hydrogen atoms slow down the anodic reaction in the first current plateau regime while not significantly affecting the other potential regimes if the chloride concentration is sufficiently high. Comparisons of the results from the hydrogen-diffusing electrodes with those from the precleaned electrodes facilitate clarifying the roles of diffusing hydrogen atoms in anodic reactions. For the hydrogen-diffusing electrode, the occurrence of the active dissolution regime is mainly from the surface cleaning effect, and the enhanced anodic reaction in the transition regime, prepassive regime, passive film growth regime, passive regime, and in some cases, transpassive regime, is due to both the electrode kinetics and the surface cleaning effect. Diffusing hydrogen would retard the anodic reaction in a specific potential regime through its combined effect with high concentration chlorides. More severe pitting is generally observed for the precleaned electrodes and the hydrogen diffusing than for the noncharged electrode. Depending on the applied potential and time as well as the chloride concentration, the hydrogen-diffusing electrode would show more extensive or severe pitting than the precleaned electrode, with some exceptions showing less severe pitting.

Study on low temperature phase change heat storage and its performance of solar and air source heat pump system

Abstract In view of the deterioration of the performance of air source heat pump at low temperature in cold regions and the large fluctuation of solar heating systems, a heat pump system with low-temperature heat storage using sodium chloride aqueous solution as the phase change thermal storage material is proposed. The system form and its operation scheme, unit energy consumption model and economic evaluation index are given. The influence of different concentrations of sodium chloride solution corresponding to different heat storage temperatures and different areas of solar collectors on the system operation economy is studied, and simulation analysis and optimization are carried out and the operation efficiency and operation economy of the system are analyzed with an actual residential building in a cold region as an example. The results show that with the increase of collector area, the lower the sodium chloride concentration, the higher the heat storage temperature and the higher the coefficient of performance (COP) of the system; the larger the collector area, the higher the COP of the system, but the payback period decreases first and then extends with the increase of the collector area. When the system sodium chloride solution concentration is 5.3% and the collector area is 372m2, there is a minimum payback period for the winter heating of 3000m2 building in this case, and at this time, the COP of the system is 2.37, which is 20% higher than that of the traditional air source heat pump. The payback period of the system is 7.7 years, and the contribution rate of the solar collector system is 53%. The solar air source heat pump system with low temperature phase change heat storage significantly improves the operation performance of the system and has good energy saving benefits.

Development and validation of analytical method by spectrophotometry UV-Vis for quantification of flavonoids in leaves of Senna occidentalis Link

Senna occidentalis Link (Fabaceae), known as “fedegoso”, is used in folk medicine due to its anti-inflammatory, antioxidant, muscle relaxant and inhibiting lipid peroxidation imputed to flavonoids contained in its composition. The species is also a constituent of processed products are commercialized in various parts of the world including Brazil, although there are few reports in the literature about the development of an analytical method for quantification of flavonoids in it. The main purpose of this research was the evaluation of an analytical methodology to determinate the content of total flavonoids in leaves of S. occidentalis, for quality control. The parameters evaluated were: drug: solvent ratio, concentration of aluminum chloride and reaction time. The quantification of total flavonoids was obtained after reaction with aluminum chloride by UV/Vis spectrophotometry. The results revealed a maximum absorption peak (λ = 392 nm) was the amount of 0.5 g of a plant raw in 100 mL of solvent and there were no significant influences between the concentrations of aluminum chloride or hydroalcoholic solutions analyzed. The evaluation of reaction time allowed to characterize the kinetics as slow, stabilizing from 60 min, choosing this as reading time. The method was specific, linear, precise, accurate and robust, according to the specifications set in RDC n. 166/2017. Finally, the results of the study showed that the measured methodology is simple and accurate and can be applied for quality assessment of the species S. occidentalis.

Electrochemical Preparation of Highly Oriented Microporous Structure Nickel Oxide Films as Promising Electrodes in Urea Oxidation

Abstract Highly oriented microporous nickel oxide films were prepared through the simple and fast anodization of nickel foils at 30 V, followed by calcination at 400 °C. Low concentrations of ammonium chloride and potassium hydroxide solutions, which were dispersed in ethylene glycol, were used as electrolytes. Microporous dimensions and large surface areas of the films were obtained by using both electrolytes. The ammonium chloride system provided a highly oriented microporous structure with excellent distribution of pores at the surface of nickel foil. On the contrary, it was not uniform in the potassium hydroxide system. Furthermore, cyclic voltammetry of the microporous films in alkaline solutions containing urea showed the highest oxidation currents at the nickel oxide films prepared in the ammonium chloride system. This nickel oxide film also showed excellent stability of the current responses, indicating that the method has potential to be applied in electrode preparation, especially urea oxidation.

Fabrication of an All-Solid-State Ammonium Paper Electrode Using a Graphite-Polyvinyl Butyral Transducer Layer

A planar solid-state ammonium-selective electrode, employing a composite mediator layer of graphite particles embedded in a polyvinyl butyral matrix on top of an inkjet-printed silver electrode, is presented in this paper. The effect of graphite powder mass fraction on the magnitude of the potentiometric response of the sensor was systematically verified using a batch-mode and a flow injection measurement setup. Under steady-state conditions, the paper electrode provided a Nernstian response of 57.30 mV/pNH4 over the concentration range of 10−5 M to 10−1 M with a detection limit of 4.8 × 10−6 M, while the analytical performance of the array in flow mode showed a narrower linear range (10−4 M to 10−1 M; 60.91 mV/pNH4 slope) with a LOD value of 5.6 × 10−5 M. The experimental results indicate that the prepared electrode exhibited high stability and fast response to different molar concentrations of ammonium chloride solutions. The pH-response of the paper NH4-ISE was also investigated, and the sensor remained stable in the pH range of 2.5–8.5. The potentiometric sensor presented here is simple, lightweight and inexpensive, with a potential application for in-situ analysis of environmental water samples.

The Role of Chloride Concentration on the Pitting Kinetics of Aluminum

This work examines the role of chloride concentration on the polarization behavior and pitting susceptibility of aluminum in highly concentrated NaCl brines. NaCl-rich brines are typically present during marine atmospheric corrosion at elevated humidity levels, which include the range from 75 % RH up to 98 % RH, corresponding to 6 M (saturated) and 0.6 M NaCl respectively at 25 oC. Although aluminum pitting is well-studied at chloride solution concentrations below 2 M (> 90% RH), electrochemical insight of aluminum atmospheric corrosion occurring at higher chloride concentrations (> 2 M [Cl-]) is hindered by lack of data. To address this, anodic polarization experiments along with post-mortem microscopy were performed on high purity Al (> 99.9 wt%) in NaCl solutions ranging from 0.6 to 6 M. Results to date show that pitting potentials and pitting transition potentials are logarithmically proportional to chloride concentration within this range, extending the applicability of previously proposed semi-empirical models to higher concentrations.1,2 Measured repassivation potentials, however, deviated considerably from previously reported trends and predictions based on measurements at lower chloride concentrations. The role of pit morphology, IR drop and hydrogen evolution during anodic polarization will be addressed to rationalize these discrepancies.SNL is managed and operated by NTESS under DOE NNSA contract DE-NA0003525. References S.T. Pride, J.R. Scully, J.L. Hudson, Journal of the Electrochemical Society, 141, 3028 (1994).J.R. Galvele, Journal of the Electrochemical Society, 123, 464 (1976).

Removal of heavy metals by surface tailored copper ion enhanced ceramic-supported-polymeric composite nanofiltration membrane

Ceramic-supported-polymeric (CSP) composite membranes combine the benefits of robust ceramic support with tunable surface properties of polymeric active layer. The present work reports the fabrication of novel CSP composite nanofiltration membranes wherein surface ionization of the membrane active layers has been carried out by a facile process of chelating copper ions with the crosslinked polyethyleneimine polymer matrix of membrane top layer. Different concentrations of copper chloride solutions were used and their effect on membrane surface properties was investigated using EDX, XPS and AFM analyses. Performance of the membranes in removal of both cationic and anionic heavy metals, namely, Ni(II), Cd(II), Pb(II), Zn(II), As(V) and Cr(VI) from aqueous solution was studied. Excellent removal (> 95%) of all the heavy metals and optimum flux was achieved in case of GPCu0.5 membrane (surface modified with 0.5 wt% copper chloride solution). No significant decrease in flux and rejection rate of the membrane during 10 h high pressure (8 bar) operation suggested longevity of the membrane. The slow release of copper ions indicated the much-expected anti-biofouling nature of the membrane. Appreciable rejection behavior of the copper ion enhanced CSP composite membrane towards multiple heavy metals demonstrates its potential for practical water treatment application.

Detection, visualization, quantification, and warning of pipe corrosion using distributed fiber optic sensors

This paper presents a distributed monitoring approach for detection, visualization, quantification, and warning for pipe corrosion using a single-mode telecommunication-grade fiber optic cable as a distributed sensor. The distributed sensor can be deployed on the surface of a pipe to measure corrosion along the pipe based on optical frequency domain reflectometry. To validate this distributed pipe corrosion monitoring approach, steel pipes were immersed in sodium chloride solution (concentration: 3.5 wt%) for corrosion tests. Strain distributions were measured and used to detect and map corrosion along the pipe. A meso-scale analytical model was developed to link the measured strains to the mass loss of pipe under corrosion. The effects of cable thickness, spatial resolution, and deployment pattern on corrosion assessment were investigated systematically. A threshold-based warning method is proposed based on the unique sensor data.

Understanding Corrosion Morphology of Duplex Stainless Steel Wire in Chloride Electrolyte

The corrosion morphology in grade 2205 duplex stainless steel wire was studied to understand the nature of pitting and the causes of the ferrite phase’s selective corrosion in acidic (pH 3) NaCl solutions at 60 °C. It is shown that the corrosion mechanism is always pitting, which either manifests lacy cover perforation or densely arrayed selective cavities developing selectively on the ferrite phase. Pits with a lacy metal cover form in concentrated chloride solutions, whereas the ferrite phase’s selective corrosion develops in diluted electrolytes, showing dependency on the chloride-ion concentration. The pit perforation is probabilistic and occurs on both austenite and ferrite grains. The lacy metal covers collapse in concentrated solutions but remain intact in diluted electrolytes. The collapse of the lacy metal cover happens due to hydrogen embrittlement. Pit evolution is deterministic and occurs selectively in the ferrite phase in light chloride solutions.

Bioprocessing of Waste Sago Pulp Fiber Based on Chloride Solution for Cellulose Isolation

The utilization of chloride solution in the bioprocessing of sago pulp fiber waste (SPFW) aims to obtain high purity cellulose before its use in making bioethanol. Before the bioprocessing, SPFW with a powder size of 149 μm was immersed in 15% (v/v) NH4OH and 5% (v/v) H2O2 solution. Bioprocessing parameters reported in this study included bioprocessing time, chloride solution concentration, and bioprocessing temperature. Based on the optimization results, the SPFW bioprocessing for 5 hours using 4% hydrochloric acid and a temperature of 95oC was the optimum condition with the acquisition of cellulose content of 67%. SPFW cellulose was confirmed by the presence of specific IR absorption peaks at wave numbers 1429.4 cm-1, 1322.4 cm-1, 1157.3 cm-1, 1110 cm-1, and 897 cm-1. Scanning Electron Microscopy (SEM) analysis shows that bioprocessing using chloride solutions produces a porous, rough, and fibrous cellulose surface. Also, the fiber length is irregular with the irregular location. Based on XRD analysis, SPFW bioprocessing produced single-phase cellulose with a crystal size of 15 nm. Physically, the bioprocessing causes the discoloration of the sago pulp fiber to turn dark brown.

Synthesis, biological investigation and catalytic application using the alcoholic extract of Black Cumin (Bunium Persicum) seeds-based silver nanoparticles

The inadequate role of silver nanoparticles is evident from their underutilization in myriad applications in the modern era. Herein we report the environment-friendly, facile, and robust synthesis of silver nanoparticles (Ag-NPs) from alcoholic extracts of black cumin (Bunium persicum) seeds to reduce and stabilise agents. The extract principally consists of nigellon, terpenoid, thymoquinone, polyene, phenylpropanoids, and phototoxic furanocoumarins. The effect of pH revealed that the BCS@Ag-NPs were more stable at neutral pH than acidic and basic. A change in the size and number of BCS@Ag-NPs was observed at high sodium chloride solution concentrations showing their instability in a concentrated salt solution. The synthesized BCS@Ag-NPs were considered significant catalysts showed by approximate 99% conversion of the 4-nitrophenolate anion into 4-aminophenol in 24 min. The surface plasmon resonance of BCS@Ag-NPs at 430 nm was recorded on UV–Vis spectrometer, and particle size ranging from 35 to 77 nm was measured through scanning electron microscopic (SEM) analysis. FTIR spectra confirmed the presence of amines, alcohols and amide functional groups at 3365 cm−1, 1646 cm−1 and 1026 cm−1 capped along with the reduction of BCS@Ag-NPs. The firm peaks for Ag atoms in BCS@Ag-NPs at almost 0.4, 3.1 and 3.2 keV in EDX analysis showed the presence of elemental silver. Nevertheless, the alcoholic seed extract and synthesized BCS@Ag-NPs exhibited excellent various pharmacological activities. Both the tested samples significantly inhibited Urease, CA-II, PDE-I. The inhibitory potential against tyrosinase was appreciated against extract as compared to BCS@Ag-NPs. The alcoholic extract was effective in the inhibition of E. coli. Both of the tested samples proved significant analgesia in the acetic acid-induced writhing model. A noticeable sedative response was observed as a compared extract. No mortality was detected in acute toxicity. In conclusion, these results provide the scientific rationale to the folklore of black cumin for GIT problems, hypertension, bronchodilation and analgesic.