The development of quantum computing hardware is facing the challenge that current-day quantum processors, comprising 50–100 qubits, already operate outside the range of quantum simulation on classical computers. In this paper we demonstrate that the simulation of limits can be a potent diagnostic tool for the resilience of quantum information hardware against chaotic instabilities potentially mitigating this problem. As a testbed for our approach we consider the transmon qubit processor, a computing platform in which the coupling of large numbers of nonlinear quantum oscillators may trigger destabilizing chaotic resonances. We find that classical and quantum simulations lead to similar stability metrics (classical Lyapunov exponents vs quantum wave function participation ratios) in systems with O(10) transmons. However, the big advantage of classical simulation is that it can be pushed to large systems comprising up to thousands of qubits. We exhibit the utility of this classical toolbox by simulating all current IBM transmon chips, including the 433-qubit processor of the Osprey generation, as well as devices with 1121 qubits (Condor generation). For realistic system parameters, we find a systematic increase of Lyapunov exponents with system size, suggesting that larger layouts require added efforts in information protection. Published by the American Physical Society 2024