Cent Of Dogs Research Articles

Clinico-diagnostic and Therapeutic Management of Ehrlichiosis in Dog

Background: The research work was undertaken to investigate the efficacy of various diagnostic tests by using conventional microscopic examination, rapid Ab detection test and molecular technique, haemato-biochemical changes, Abdominal organs changes using ultrasonography, and therapeutic efficacy of different treatment protocols on Canine Monocytic Ehrlichiosis (CME) infected dogs from in and around Navsari, Gujarat, India. Methods: 69 dogs suspected of ehrlichiosis based on clinical signs and hematological values and then subjected to blood and buffy coat smear examination, rapid Ab detection test and PCR based assay targeting 16S rRNA gene. The pre and post-treatment haematology and biochemical analysis of treatment groups along with all the positive dogs were performed. Further, all the treatment group dogs were subjected to ultrasound for evaluating organ abnormalities. Modified Clinical Sign Grading (MCSG) score for CME-infected dogs was carried out to evaluate therapeutic responses based on minimizing the clinical score. Descriptive statistics along with Student t-test and One-way analysis of variance (ANOVA) followed by DMRT was performed to compare differences between means wherever applicable. Result: CME incidence among the 69 suspected cases was 49.28%. Out of 69 suspected dogs, Ehrlichial inclusions or morulae in the monocytes could be identified in only 4.35% of blood smears and 10.14% of buffy coat smears examined by Giemsa and or Field-stained and 15.94% of dogs were found positive for Ehrlichia genus by PCR. 72.5 per cent of dogs were found positive for antibodies to E. canis, out of 40 dogs. The sensitivity of blood smear examination, buffy coat smear examination, and thrombocytopenia was 10.34%, 24.14% and 89.66%, respectively. The specificity of all the diagnostic tests was 100%. The anemia along with leucopenia, were the most significant hematological alteration recorded while ALP, creatinine, and BUN were elevated and albumin was significantly decreased in CME-infected dogs. Significant improvement of haemato-biochemical parameters towards normalcy in both treatment groups. However, a higher percentage of reduction was observed in the clinical score of imidocarb treated CME affected dogs than in the oxy-doxycycline therapy after 14 days.

Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis

Acute kidney injury (AKI) is a serious complication of infectious diseases like babesiosis and leptospirosis in dogs. Both the diseases show similar clinical manifestations, due to which timely differential diagnosis often gets delayed. The present study focused on diagnosis of major infectious agents causing AKI and its grading in dogs. Peripheral blood smear examination and PCR were used for the diagnosis of babesiosis. Leptospirosis was screened using PCR and MAT and was later confirmed by MAT on paired sera sample. Diagnosis of AKI was made based on the increase in serum creatinine levels ≥0.3 mg/dL within 48 h of presentation. Staging of animals was carried out as per International Renal Interest Society (IRIS) guidelines. All the dogs with confirmed leptospirosis and 15 per cent of dogs with babesiosis were diagnosed with AKI. The timely diagnosis of AKI in dogs during their initial stages helps to regain normal renal function within short-term treatment itself.

Occurrence of canine mammary and skin/ subcutaneous neoplasms in and around Thrissur district of Kerala during 2017-2020: A review of 265 cases

The study was conducted in 265 clinical cases of mammary and skin/ subcutaneous neoplasms in dogs presented to University Veterinary Hospitals Mannuthy and Kokkalai during a period of 36 months from October 2017 to September 2020. Mammary neoplasms were found more in females (51.7 per cent) than in males whereas skin and subcutaneous neoplasms were found more in male dogs (48.3 per cent). The maximum occurrence of neoplasms was recorded in the age group of eight to twelve years (38.5 per cent) whereas least occurrence was noticed in the age group up to four years (9 per cent). Labrador and Rottweiler breeds were found more affected with neoplasms (38 per cent each) with highest occurrence of mammary neoplasms in inguinal mammary glands (35.03 per cent) and highest occurrence of skin/ subcutaneous neoplasms on sites involving trunk region (14.06 per cent cases). Eighty-three per cent of the neoplasm cases in the present study were pet dogs with a greater number of dogs maintained in outdoor kennels and 17 per cent of neoplasm was found in free-roaming dogs rescued from streets. Out of total 265 dogs, 37.73 per cent dogs were found to be having commercial dog food as their main feed and 32 per cent dogs were fed with a mixed diet of homemade food and commercial dog food. Among the cases, 14.71 per cent dogs had a previous history of cancer surgery

Survey investigating the reasons why UK-based gundogs ceased working between 2010 and 2019.

To determine the longevity of the working life of gundogs in the UK, whether owners' considered retirement was premature and to identify risk factors associated with such work. A web-based survey seeking owner information as to the longevity of their dogs' working life and why they were retired, euthanised or died. The sample population is six hundred sixty-five dogs. The median age at which Springer spaniels stopped work was 11 years and for Cocker spaniels, it was 9 years. The median age for Labrador retrievers was 10 years; for Golden retrievers, 11 years and Flat-coated retrievers, 9.5 years. Cocker spaniels stopped work at a significantly younger age than Springer spaniels (p=0.0003) or Labrador retrievers (p=0.0407). There was no significant difference between the other major breeds. The majority of owners (54.3%) were satisfied with the working lifespan of their dog. Seventy per cent of dogs were retired, the three most prevalent reasons being lameness (25.2%), old age (23.7%) and deafness (7.8%). Forty-four dogs died (6.6%) and 158 (24%) were euthanised, with cancer (58%) being the most common reason. No work-related issues were identified and gundogs appear to have similar causes of mortality to the general canine population.

Household Livestock in the Eruwa District of the Ibarapa Division, Oyo State, Nigeria

NUMBERS of sheep, goats, pigs, chicken, dogs and cats classified as adult males, adult females and young were counted in Eruwa Ibarapa Division, Oyo State, Nigeria and its associated villages during July and August 1974. Counts involved a total of 1975 households, 769 in the town and 506 in the villages; 9.42 per cent kept sheep, 58.44 per cent goats, 4.32 per cent pigs, 88.00 per cent chickens, 28.16 per cent dogs and 27.38 per cent cats. Means of animals per town household were 4.59 sheep, 3.58 goats, 11.95 pigs, 14.73 chickens, 1.89 dogs and 1.62 cats; means per village household were 6.75 sheep, 5.01 goats, no pigs, 17.60 chickens, 2.0r dogs and 1.81 cats, The investigation has provided a sampling frame from which samples can be drawn for specific investigations and continuing surveillances.

A description of blend electrolysis for treatment of canine distichiasis: 78 cases (2012–2017)

ObjectiveTo describe a population of dogs treated with blend electrolysis for distichiasis at The Royal Veterinary College and report the complications seen.MethodsIn part 1, records were reviewed from 2012 to...

Idiopathic epilepsy in dogs: insights into factors that may predict upcoming seizure activity

Idiopathic epilepsy (IE) is the most common chronic neurological disorder in dogs. Most dogs with IE first experience seizures when they are under six years old, and they usually require...

Clinical features and long-term follow-up of 70 cases of canine idiopathic eosinophilic lung disease

BackgroundCanine idiopathic eosinophilic lung disease (ELD) is sparsely documented in the literature.MethodsClinical presentation and outcome of dogs diagnosed with ELD (eosinophilic bronchitis or eosinophilic bronchopneumonia) were reviewed. Subgroups were made...

An observational study of pet feeding practices and how these have changed between 2008 and 2018

BackgroundPet owners have many feeding options, some may be considered unconventional by veterinary practitioners. Provision of appropriate nutrition is a basic requirement, with adverse health outcomes possible when a pet...

Intervertebral disc disease and aortic thromboembolism are the most common causes of acute paralysis in dogs and cats presenting to an emergency clinic

BackgroundAcute paralysis is a common presentation in small animal emergency clinics, but the aetiological prevalence has not been reported. Knowledge of diagnosis frequency aids prioritisation of differential diagnoses, facilitates resource...

Estimation of the prevalence of idiopathic epilepsy and structural epilepsy in a general population of 900 dogs undergoing MRI for epileptic seizures

Due to variation in study designs the prevalence of idiopathic epilepsy (IE) and structural epilepsy (SE) in dogs is largely unknown. The objective was to provide estimates of the prevalence...

Dysautonomia in 53 cats and dogs: retrospective review of clinical data and outcome

Dysautonomia is a disease characterised by degeneration of autonomic neurons. The aim of this study was to perform a retrospective multicentre review of clinical data relating to cats and dogs diagnosed with dysautonomia and to evaluate their outcome. Cats (n=34) and dogs (n=19) with clinical signs consistent with dysautonomia were considered for this retrospective study. Reported clinical findings included oesophageal and gastrointestinal dysmotility and distension, urinary retention, reduced or absent tear production, third eyelid protrusion and inappropriate mydriasis. Treatment was supportive and included gastrointestinal prokinetics, feeding tube placement (oesophageal and percutaneous endoscopic gastrostomy tubes) and medications to treat urinary retention. The survival to discharge was 29 per cent in cats and 47 per cent in dogs. The overall survival in cats was 21 per cent and that in dogs was 32 per cent. Survival of greater than 2 years was seen in six cats and in three dogs. This paper illustrates that some animals are able to survive this disease and can have a good long-term prognosis, which is an infrequently reported finding for this disease.

Importing rescue dogs into the UK: reasons, methods and welfare considerations

BackgroundRescuing dogs from overseas is increasing in popularity but has associated risks. This study is the first to investigate the reasons why people bring rescue dogs into the UK from...

Antimicrobial prescriptions and adherence to prudent use guidelines for selected canine diseases in Switzerland in 2016

BackgroundAntimicrobial resistance is an increasing problem in human and veterinary medicine and is closely linked to the use of antimicrobials. The objective of this study was to describe antimicrobial prescriptions...

Effect of an intraoperative infusion of amino acids on body temperature, serum biochemistry, serum insulin and recovery variables in healthy dogs undergoing ovariohysterectomy

Change in body temperature (BT), serum biochemistry and recovery variables were compared after infusion of amino acids (AA) or lactated Ringer’s solution (LRS) in dogs undergoing ovariohysterectomy. Dogs received eight...

Soft tissue sarcoma in the dog: an update

Soft tissue sarcomas (STS) are a large group of tumours derived from mesenchymal tissues. STS may arise anywhere in the body, but most commonly appear on the appendicular skeleton. They...

Concurrent endocrine neoplasias in dogs and cats: a retrospective study (2004–2014)

Multiple endocrine neoplasia (MEN) is a well-known syndrome in human medicine, whereas only a few cases of concurrent endocrine neoplasias have been reported in dogs and cats. The aim of...

Frequency of DEA 1 antigen in 1037 mongrel and PUREBREED dogs in ITALY

BackgroundThe prevalence of dog erythrocyte antigen (DEA 1) in canine population is approximately 40–60%. Often data are limited to a small number of breeds and/or dogs. The aims of this study were to evaluate frequency of DEA 1 in a large population of purebred and mongrel dogs including Italian native breeds and to recognize a possible association between DEA 1 and breed, sex, and genetic and phenotypical/functional classifications of breeds. Frequencies of DEA 1 blood group collected from screened/enrolled blood donors and from healthy and sick dogs were retrospectively evaluated. The breed and the sex were recorded when available. DEA 1 blood typing was assessed by immunocromatographic test on K3EDTA blood samples. The prevalence of DEA 1 antigen was statistically related to breed, gender, Fédération Cynologique Internationale (FCI) and genotypic grouping.ResultsSixty-two per cent dogs resulted DEA 1+ and 38% DEA 1-. DEA 1- was statistically associated with Dogo Argentino, Dobermann, German Shepherd, Boxer, Corso dogs, the molossian dogs, the FCI group 1, 2 and 3 and the genetic groups “working dogs” and “mastiff”. DEA 1+ was statistically associated with Rottweiler, Briquet Griffon Vendéen, Bernese mountain dog, Golden Retriever, the hunting breeds, the FCI group 4, 6, 7 and 8 and the genetic groups “scent hounds” and “retrievers”. No gender association was observed.ConclusionsData obtained by this work may be clinically useful to drive blood donor enrollment and selection among different breeds.

Outcome comparison in dogs with a presumptive diagnosis of thoracolumbar fibrocartilaginous embolic myelopathy and acute non-compressive nucleus pulposus extrusion

Dogs with fibrocartilaginous embolic myelopathy (FCEM) or acute non-compressive nucleus pulposus extrusion (ANNPE) are reported to have a fair prognosis; however, persistent motor/autonomic deficits are possible. Specific MRI patterns have...

Emergence of Brucella suis in dogs in New South Wales, Australia: clinical findings and implications for zoonotic transmission.

BackgroundAnimal reservoirs of brucellosis constitute an ongoing threat to human health globally, with foodborne, occupational and recreational exposures creating opportunities for transmission. In Australia and the United States, hunting of feral pigs has been identified as the principal risk factor for human brucellosis due to Brucella suis. Following increased reports of canine B. suis infection, we undertook a review of case notification data and veterinary records to address knowledge gaps about transmission, clinical presentation, and zoonotic risks arising from infected dogs.ResultsBetween 2011 and 2015, there was a 17-fold increase in the number of cases identified (74 in total) in New South Wales, Australia. Spatial distribution of cases largely overlapped with high feral pig densities in the north of the state. Ninety per cent of dogs had participated directly in pig hunting; feeding of raw feral pig meat and cohabitation with cases in the same household were other putative modes of transmission. Dogs with confirmed brucellosis presented with reproductive tract signs (33 %), back pain (13 %) or lameness (10 %); sub-clinical infection was also common (40 %). Opportunities for dog-to-human transmission in household and occupational environments were identified, highlighting potential public health risks associated with canine B. suis infection.ConclusionsBrucellosis due to B. suis is an emerging disease of dogs in Australia. Veterinarians should consider this diagnosis in any dog that presents with reproductive tract signs, back pain or lameness, particularly if the dog has a history of feral pig exposure. Moreover, all people in close contact with these dogs such as hunters, household contacts and veterinary personnel should take precautions to prevent zoonotic transmission.