Bubble Detectors Research Articles

Investigating in-field and out-of-field neutron contamination in high-energy medical linear accelerators based on the treatment factors of field size, depth, beam modifiers, and beam type

PurposeWe analysed the effects of field size, depth, beam modifier and beam type on the amount of in-field and out-of-field neutron contamination for medical linear accelerators (linacs). MethodsMeasurements were carried out for three high-energy medical linacs of Elekta Synergy Platform, Varian Clinac DHX High Performance and Philips SL25 using bubble detectors. The photo-neutron measurements were taken in the first two linacs with 18 MV nominal energy, whereas the electro-neutrons were measured in the three linacs with 9 MeV, 10 MeV, 15 MeV and 18 MeV. ResultsThe central neutron doses increased with larger field sizes as a dramatic drop off was observed in peripheral areas. Comparing with the jaws-shaped open-field of 10 × 10 cm, the motorised and physical wedges contributed to neutron contamination at central axis by 60% and 18%, respectively. The similar dose increment was observed in MLC-shaped fields. The contributions of MLCs were in the range of 55–59% and 19–22% in Elekta and Varian linacs comparing with 10 × 10 and 20 × 20 cm open fields shaped by the jaws, respectively. The neutron doses at shallow depths were found to be higher than the doses found at deeper regions. The electro-neutron dose at the 18 MeV energy was higher than the doses at the electron energies of 15 MeV and 9 MeV by a factor of 3 and 50, respectively. ConclusionThe photo- and electro-neutron dose should be taken into consideration in the radiation treatment with high photon and electron energies.

Avoidance of Airembolism during Extra Corporeal Life Support (ECLS)

Objectives: Air embolisms may result from negative pressure within the venous system while on Extracorporeal Life Support (ECLS). During an orthotopic heart transplantation with postcardiotomic ECLS-implantation an air embolism occurred. Due to usage of an air bubble detector within the venous line and an electronic clamp within the arterial line, an entry of air into the arterial system could be prevented.

Ion acceleration and D-D nuclear fusion in laser-generated plasma from advanced deuterated polyethylene.

Deuterated polyethylene targets have been irradiated by means of a 1016 W/cm2 laser using 600 J pulse energy, 1315 nm wavelength, 300 ps pulse duration and 70 micron spot diameter. The plasma parameters were measured using on-line diagnostics based on ion collectors, SiC detectors and plastic scintillators, all employed in time-of-flight configuration. In addition, a Thomson parabola spectrometer, an X-ray streak camera, and calibrated neutron dosimeter bubble detectors were employed. Characteristic protons and neutrons at maximum energies of 3.0 MeV and 2.45 MeV, respectively, were detected, confirming that energy spectra of reaction products coming from deuterium-deuterium nuclear fusion occur. In thick advanced targets a fusion rate of the order of 2 × 108 fusions per laser shot was calculated.

Response of the bubble detector to neutrons of various energies.

A series of Monte-Carlo simulations has been performed in order to investigate the response of the bubble detector to monoenergetic neutrons of various energies. The work was driven by the need to better understand the energy dependence of the detector for applications in space, where the neutron spectrum has a significant component with energy of >20 MeV. The response to neutrons in the range of a few keV to 500 MeV has been calculated, and good agreement between the simulations and experimental data is demonstrated over the entire energy range.

Photonuclear reaction based high-energy x-ray spectrometer to cover from 2 MeV to 20 MeV.

A photonuclear-reaction-based hard x-ray spectrometer is developed to measure the number and energy spectrum of fast electrons generated by interactions between plasma and intense laser light. In this spectrometer, x-rays are converted to neutrons through photonuclear reactions, and the neutrons are counted with a bubble detector that is insensitive to x-rays. The spectrometer consists of a bundle of hard x-ray detectors that respond to different photon-energy ranges. Proof-of-principle experiment was performed on a linear accelerator facility. A quasi-monoenergetic electron bunch (Ne = 1.0 × 10(-6) C, Ee = 16 ± 0.32 MeV) was injected into a 5-mm-thick lead plate. Bremsstrahlung x-rays, which emanate from the lead plate, were measured with the spectrometer. The measured spectral shape and intensity agree fairly well with those computed with a Monte Carlo simulation code. The result shows that high-energy x-rays can be measured absolutely with a photon-counting accuracy of 50%-70% in the energy range from 2 MeV to 20 MeV with a spectral resolution (Δhν/hν) of about 15%. Quantum efficiency of this spectrometer was designed to be 10(-7), 10(-4), 10(-5), respectively, for 2-10, 11-15, and 15-25 MeV of photon energy ranges.

Sci-Fri PM: Dosimetry-02: A Nested Neutron Spectrometer to Measure Neutron Spectra in Radiotherapy

During high-energy radiotherapy treatments, neutrons are produced in the head of the linac through photonuclear interactions. This has been a concern for many years as photoneutrons contribute to the accepted, yet unwanted, out-of-field doses that pose an iatrogenic risk to patients and an occupational risk to personnel. Presently, in-room neutron measurements are difficult and time-consuming and have traditionally been carried out using Bonner spheres with activation foils and TLDs. In this work, a new detector, the Nested Neutron Spectrometer (NNS) is tested for use in radiotherapy bunkers. The NNS is designed for easy handling and is more practical than the traditional Bonner spheres. The NNS, operated in current mode, was used to measure the dose equivalent, average energy and energy spectrum at several positions in a radiotherapy bunker. The average energy and spectra were compared to Monte Carlo simulations while the dose equivalent was compared to bubble detector measurements. The average energies, as measured by the NNS and Monte Carlo simulations, differed by approximately 30% across the bunker. Measurements of the dose equivalent using the NNS and the bubble detectors agreed within 50% in the maze and less than 10% close to the linac head. Apart from some discrepancies at thermal energies, we also found reasonable agreement between NNS-measured and Monte Carlo-simulated spectra at a number of locations within our radiotherapy bunker. Our results demonstrate that the NNS is a suitable detector to be used in high dose-rate radiotherapy environments.

Acoustic monitoring of gas emissions from the seafloor. Part II: a case study from the Sea of Marmara

A rotating, acoustic gas bubble detector, BOB (Bubble OBservatory) module was deployed during two surveys, conducted in 2009 and 2011 respectively, to study the temporal variations of gas emissions from the Marmara seafloor, along the North Anatolian Fault zone. The echosounder mounted on the instrument insonifies an angular sector of 7° during a given duration (of about 1 h). Then it rotates to the next, near-by angular sector and so forth. When the full angular domain is insonified, the “pan and tilt system” rotates back to its initial position, in order to start a new cycle (of about 1 day). The acoustic data reveal that gas emission is not a steady process, with observed temporal variations ranging between a few minutes and 24 h (from one cycle to the other). Echo-integration and inversion performed on the acoustic data as described in the companion paper of Leblond et al. (Mar Geophys Res, 2014), also indicate important variations in, respectively, the target strength and the volumetric flow rates of individual sources. However, the observed temporal variations may not be related to the properties of the gas source only, but reflect possible variations in sea-bottom currents, which could deviate the bubble train towards the neighboring sector. During the 2011 survey, a 4-component ocean bottom seismometer (OBS) was co-located at the seafloor, 59 m away from the BOB module. The acoustic data from our rotating, monitoring system support, but do not provide undisputable evidence to confirm, the hypothesis formulated by Tary et al. (2012), that the short-duration, non-seismic micro-events recorded by the OBS are likely produced by gas-related processes within the near seabed sediments. Hence, the use of a multibeam echosounder, or of several split beam echosounders should be preferred to rotating systems, for future experiments.

SU‐E‐T‐495: Neutron Induced Electronics Failure Rate Analysis for a Single Room Proton Accelerator

Purpose:To determine the failure rate as a function of neutron dose of the range modulator's servo motor controller system (SMCS) while shielded with Borated Polyethylene (BPE) and unshielded in a single room proton accelerator.Methods:Two experimental setups were constructed using two servo motor controllers and two motors. Each SMCS was then placed 30 cm from the end of the plugged proton accelerator applicator. The motor was then turned on and observed from outside of the vault while being irradiated to known neutron doses determined from bubble detector measurements. Anytime the motor deviated from the programmed motion a failure was recorded along with the delivered dose. The experiment was repeated using 9 cm of BPE shielding surrounding the SMCS.Results:Ten SMCS failures were recorded in each experiment. The dose per monitor unit for the unshielded SMCS was 0.0211 mSv/MU and 0.0144 mSv/MU for the shielded SMCS. The mean dose to produce a failure for the unshielded SMCS was 63.5 ± 58.3 mSv versus 17.0 ±12.2 mSv for the shielded. The mean number of MUs between failures were 2297 ± 1891 MU for the unshielded SMCS and 2122 ± 1523 MU for the shielded. A Wilcoxon Signed Ranked test showed the dose between failures were significantly different (P value = 0.044) while the number of MUs between failures were not (P value = 1.000). Statistical analysis determined a SMCS neutron dose of 5.3 mSv produces a 5% chance of failure. Depending on the workload and location of the SMCS, this failure rate could impede clinical workflow.Conclusion:BPE shielding was shown to not reduce the average failure of the SMCS and relocation of the system outside of the accelerator vault was required to lower the failure rate enough to avoid impeding clinical work flow.

Bubble-detector measurements in the Russian segment of the International Space Station during 2009-12

Measurements using bubble detectors have been performed in order to characterise the neutron dose and energy spectrum in the Russian segment of the International Space Station (ISS). Experiments using bubble dosemeters and a bubble-detector spectrometer, a set of six detectors with different energy thresholds that is used to determine the neutron spectrum, were performed during the ISS-22 (2009) to ISS-33 (2012) missions. The spectrometric measurements are in good agreement with earlier data, exhibiting expected features of the neutron energy spectrum in space. Experiments using a hydrogenous radiation shield show that the neutron dose can be reduced by shielding, with a reduction similar to that determined in earlier measurements using bubble detectors. The bubble-detector data are compared with measurements performed on the ISS using other instruments and are correlated with potential influencing factors such as the ISS altitude and the solar activity. Surprisingly, these influences do not seem to have a strong effect on the neutron dose or energy spectrum inside the ISS.

Instrument intercomparison in the high-energy mixed field at the CERN-EU reference field (CERF) facility

This paper discusses an intercomparison campaign performed in the mixed radiation field at the CERN-EU (CERF) reference field facility. Various instruments were employed: conventional and extended-range rem counters including a novel instrument called LUPIN, a bubble detector using an active counting system (ABC 1260) and two tissue-equivalent proportional counters (TEPCs). The results show that the extended range instruments agree well within their uncertainties and within 1σ with the H*(10) FLUKA value. The conventional rem counters are in good agreement within their uncertainties and underestimate H*(10) as measured by the extended range instruments and as predicted by FLUKA. The TEPCs slightly overestimate the FLUKA value but they are anyhow consistent with it when taking the comparatively large total uncertainties into account, and indicate that the non-neutron part of the stray field accounts for ∼30 % of the total H*(10).

Gamma photon techniques for detection of nucleation in superheated emulsion detectors for neutron dosimetry

Application of transmission and scattering gamma photon techniques for calibration of superheated emulsion detectors used for neutron dosimetry is described. The bubbles nucleated in the detector due to neutron exposure generate detectable changes in both attenuation and scattering properties of the medium, and the magnitude of change in properties depends on population density of bubbles nucleated and in turn is proportional to neutron dose. The experimental set-up consists of (137)Cs and (241)Am sources and an HPGe detector-based gamma-ray spectrometer. An indigenously developed bubble detector and a commercially available one (BTI, Canada) are used in the present study. Theoretical models for the variation in transmitted and scattered intensities through the bubble detector as a function of neutron dose are formulated, and the experimental results obtained are found to be in good agreement with the models. In the neutron dose region studied, the transmission technique shows better sensitivity than scattering technique.

SU‐E‐T‐35: Extracting a Neutron Dose Using Only TLDs (Thermoluminescent Detectors)

Purpose: To test the use of TLDs for out‐of‐field neutron measurements and demonstrate the calibration and calculations necessary to extract a neutron dose by using TLD 600 chips, which measure photons plus neutrons, and TLD 700 chips, which measure only photons. For treatments requiring high‐energy photons or protons, secondary neutron doses may become a factor and TLDs provide many advantages in a clinical setting over conventional neutron dosimeters. Methods: A set of lithium fluoride TLDs (thermoluminescent detectors) consisting of 100, 600 and 700 series Rexon TLDs were arranged at set distances in and out of field of 6MV and 18MV photon beams from an Elekta Precise Treatment System. All TLD chips were read out using a Rexon System 310 reader and raw glow output data was exported for data analysis. Results: Examination of the integrated TLD glow curves shows an energy dependent response and a higher reading for TLD 600 chips as the distance or angle from the beam field increases for the 18MV beam. At a low neutron dose, correct integration interval must be used extracted a signal above noise. Conclusion: This work demonstrates the feasibility of neutron measurements using only TLDs as opposed to TLDs with CR39, bubble detectors, diamond detectors or WENDI detectors. TLDs are commercially available in different sensitivities and relatively cheap. We speculate that the TLD 600 chips will continue to read neutron doses at large distances to its neutron cross section. Furthermore they allow for spatial resolution and in vivo measurements. With calibration for neutron doses and photon energy ranges, a quantitative neutron dose is possible. This integration and subtraction method will be used in future investigation to directly quantify neutron doses spatially with respect to the beam and for different beam characteristics.

Peripheral doses in radiotherapy: A comparison between IMRT, VMAT and Tomotherapy

The goal of this intercomparison is to determine the peripheral doses during treatment of prostate and head and neck (H&N) cancers. In the case of prostate cancer, two different treatment techniques are compared: intensity-modulated radiation therapy (IMRT – 10 MV and 18 MV), on a Varian Clinac 2100 C/D and Tomotherapy. VMAT (also on a Varian Clinac 2100 C/D) was compared to Tomotherapy, for H&N cancer. The treatment devices are located at the university hospitals of Leuven and Brussels, respectively. A common treatment protocol was agreed between the two clinical centers and this same protocol was used by each partner. For the higher energy modalities (10 MV and 18 MV) we also assessed the neutron contribution to the total dose, by using bubble detectors. In this way, the performance (in terms of peripheral doses) of the different treatment techniques, when faced with the same dose distribution constraints, was evaluated. The doses were evaluated with an anthropomorphic phantom loaded with TLD detectors. Summarizing our results, we can conclude that low energy radiation techniques, namely VMAT and Tomotherapy, have more interesting performances when compared to IMRT at energies of 10 MV and 18 MV, with respect to peripheral dose. On the one hand the former are associated with lower photon doses and, on the other hand, there is no contribution from neutrons to the total dose.

Investigation of a Bubble Detector based on Active Electrolocation of Weakly Electric Fish

Weakly electric fish employ active electrolocation for navigation and object detection. They emit an electric signal with their electric organ in the tail and sense the electric field with electroreceptors that are distributed over their skin. We adopted this principle to design a bubble detector that can detect gas bubbles in a fluid or, in principle, objects with different electric conductivity than the surrounding fluid. The evaluation of the influence of electrode diameter on detecting a given bubble size showed that the signal increases with electrode diameter. Therefore it appears that this detector will be more appropriate for large sized applications such as bubble columns than small sized applications such as bubble detectors in dialysis.

Experimental investigation of bubble occurrence and locality distribution of bubble detectors bombarded with high-energy helium ions

Abstract Large-sized bubble detectors with microscopic droplets of superheated liquids of dichlorodifluoromethane (Freon-12), dichlorotetrafluoroethane (Freon-114), tetrafluoroethane (Freon-134a), and mixture of Freon-12 and Freon-114, respectively, were irradiated with 150 MeV/amu helium ions at the HIMAC accelerator in NIRS, Chiba, Japan. Distributions of bubbles produced by the helium ions have been studied in each type of the detectors. The origin of the bubbles has been investigated. The detection efficiency of each type of the bubble detectors for helium ions with respect to the energy of the ions has been obtained. The phenomenon of bubble occurrence and its possible applications to the determination of He intensity from accelerators, research of track formation mechanism, energy loss straggling and neutron detection in the space and at higher altitude are discussed.

Acoustic attenuation, phase and group velocities in liquid-filled pipes III: Nonaxisymmetric propagation and circumferential modes in lossless conditions

Equations for the nonaxisymmetric modes that are axially and circumferentially propagating in a liquid-filled tube with elastic walls surrounded by air/vacuum are presented using exact elasticity theory. Dispersion curves for the axially propagating modes are obtained and verified through comparison with measurements. The resulting theory is applied to the circumferential modes, and the pressures and the stresses in the liquid-filled pipe are calculated under external forced oscillation by an acoustic source. This provides the theoretical foundation for the narrow band acoustic bubble detector that was subsequently deployed at the Target Test Facility (TTF) of the Spallation Neutron Source (SNS) at Oak Ridge National Laboratory (ORNL), TN.

Fault Tolerant Air Bubble Sensor using Triple Modular Redundancy Method

Detection of air bubbles in the blood is important for various medical treatments that use Extracorporeal Blood Circuits (ECBC), such as hemodialysis, hemofiltration and cardio-pulmonary bypass. Therefore a reliable air bubble detector is needed. This study presents the design of a new fault tolerant air bubble detector. Triple Modular Redundancy (TMR) method is used on the sensor section. A voter circuit of the Triple Modular Redundancy will choose one of three sensor outputs to be processed further. Application of Triple Modular Redundancy will prevent errors in the detection of air bubbles, especially if the sensor fails to work.

Microembolism and Catheter Ablation I

Background— Cerebral diffusion-weighted MRI lesions have been observed after catheter ablation of atrial fibrillation. We hypothesized that conditions predisposing to microembolization could be identified using a porcine model of pulmonary vein ablation and an extracorporeal circulation loop. Methods and Results— Ablations of the pulmonary veins were performed in 18 swine with echo monitoring. The femoral artery and vein were cannulated and an extracorporeal circulation loop with 2 ultrasonic bubble detectors and a 73-μm filter were placed in series. Microemboli and microbubbles were compared between ablation with an irrigated radiofrequency system (Biosense-Webster) and a phased radiofrequency multielectrode system (pulmonary vein ablation catheter [PVAC], Medtronic, Inc, Carlsbad, CA) in unipolar and 3 blended unipolar/bipolar modes. Animal pathology was examined. The size and number of microbubbles observed during ablation ranged from 30 to 180 μm and 0 to 3253 bubbles per ablation. Microbubble volumes with PVAC (29.1 nL) were greater than with irrigated radiofrequency (0.4 nL; P =0.045), and greatest with type II or III microbubbles on transesophageal echocardiography. Ablation with the PVAC showed fewest microbubbles in the unipolar mode ( P =0.012 versus bipolar). The most occurred during bipolar energy delivery with overlap of proximal and distal electrodes (median microbubble volume, 1744 nL; interquartile range, 737–4082 nL; maximum, 19 516 nL). No cerebral MRI lesions were seen, but 2 animals had renal embolization. Conclusions— Left atrial ablation with irrigated radiofrequency and PVAC catheters in swine is associated with microbubble and microembolus production. Avoiding overlap of electrodes 1 and 10 on PVAC should reduce the microembolic burden associated with this procedure.

Introduction to dosimetry and risk estimation of second cancer induction following radiotherapy

This brief review of dosimetry in second cancer dosimetry introduces work carried out by Working Group 9 (Radiation Protection Dosimetry in Medicine) of the European Radiation Dosimetry Group (EURADOS). The work described in the following papers in this edition was presented at a Workshop on Dosimetry for Second Cancer Risk Estimation given at the EURADOS Annual meeting in Vienna on February 8th 2012. The work concentrates on the measurement of out-of-field doses in water tanks and BOMAB-like phantoms using a variety of dosimeters to measure photon and neutron doses. These include optically stimulated luminescence (OSL), radiophotoluminescence (RPL) and thermoluminescence (TLD) dosimeters for photon dosimetry (together with ion chambers for reference measurements traceable to primary standards) and track etch and bubble detectors for neutron measurements. A discussion of the various phantoms available for these measurements is presented together with a brief introduction to a model for the relationship between organ doses and the risk of induction of second cancers. The estimation of second cancer risks is not trivial and involves processes which are currently incompletely understood. However, progress in this field requires a robust foundation and methodology for the measurement or calculation of organ doses following radiotherapy, so that risks can be placed in perspective, algorithms for out-of-field doses can be compared with measured data, and future epidemiological studies may have a reliable foundation of organ dosimetry for retrospective dosimetry studies.

Observation of neutrons in the interaction of high intensity laser pulses with solid targets

We report an experimental study on fusion neutron generation from deuterated polyethylene (CD2)n target irradiated by 400 mJ, 45 femtosecond laser pulses focused to an intensity >10 18 W/cm 2 .T he fusion neutron signal has been detected using a CR-39 detector, a bubble detector, and also confirmed by a neutron time of flight detector. In addition, substantial bremsstrahlung X-ray radiation of MeV energy was also observed. These MeV X-rays have been used to trigger (, n) reaction in Be and Cu targets and the resulting photo-neutrons were detected on a BF3 and a bubble detector.