Body Temperature Recovery Time Research Articles

Bundled care combined with animated educational videos can promote the recovery of severe pneumonia in children: A case-control study.

In this study, we analyzed the efficacy of animated educational videos and group nursing in the treatment of severe pneumonia in children. A total of 140 patients with severe pneumonia in our hospital from October 2022 to October 2023 were selected as the research subjects, and they were divided into a control group and an observation group. The control group received routine care, while the observation group received animated educational videos and cluster nursing interventions. The treatment effects of the 2 groups of patients were compared. Clinical indicators such as body temperature recovery time, blood oxygen saturation recovery time, heart rate recovery time, consciousness recovery time, and respiratory rate recovery time were compared between the 2 groups of patients. The results showed that the temperature recovery time, oxygen saturation recovery time, heart rate recovery time and respiratory rate recovery time in observation group were significantly different from those in control group (P < .05). Univariate analysis showed that families with or without anxiety disorder had statistically significant differences in economic conditions, extrapulmonary complications, nursing methods and other aspects. Logistic multivariate regression analysis showed that nursing methods, extrapulmonary complications, and poor economic conditions (income < 5000) were risk factors for anxiety among family members of severe pneumonia patients, while good economic conditions (income > 5000) were protective factors. So, animated educational videos and bundled care can effectively improve the nursing effectiveness of children with severe pneumonia and promote their recovery.

Efficacy of different doses of corticosteroids in treating severe COVID-19 pneumonia

BackgroundTo investigate the efficacy of different doses of corticosteroids in treating severe coronavirus disease 2019 (COVID-19) pneumonia.MethodsBetween May 01, 2023, and June 20, 2023, 48 patients with severe COVID-19 pneumonia were treated at the Department of Respiratory and Critical Care Medicine of Jinan Fourth People's Hospital. The observation group (21 patients) received standard care and high-dose corticosteroids, (high-dose group). The control group (27 patients) received standard care and low-dose corticosteroids (low-dose group). We collected baseline data and recorded inflammatory marker levels after 3 days of treatment, body temperature recovery time, length of stay, and 28-day all-cause mortality. The results of outpatient follow-up were recorded after 1 month.ResultsThere were no significant differences in 28-day mortality and length of stay. The number of days it took for body temperature to return to normal in the high-dose group was less than in the low-dose group. The high-dose group had significantly more reduced inflammatory factors (C-reactive protein (CRP), interleukin-6 (IL-6). A total of 20 discharged patients were given 8–16 mg of methylprednisolone, depending on chest computed tomography (CT) and clinical symptoms after 1 month; in all discharged patients using oral corticosteroids, CT features improved.ConclusionHigh-dose corticosteroids had a significantly positive effect on the reduction of inflammatory factors and shortening body temperature recovery time. In the treatment of severe COVID-19 pneumonia, early administration of high-dose, short-course corticosteroids should be implemented.

Effect of comprehensive nursing intervention on the efficacy of spleen aminopeptide combined with aerosol inhalation in the treatment of pediatric pneumonia.

To analyze the effect of comprehensive nursing intervention on the efficacy of spleen aminopeptide combined with aerosol inhalation in the treatment of pediatric pneumonia. This is a retrospective study. Eighty children with pneumonia admitted to Baoding children's Hospital from March 2020 to March 2021 were included and randomly divided into two groups. Children in the control group received routine treatment and nursing measures, while those in the experimental group received comprehensive nursing intervention on the basis of routine treatment in the control group. The differences in clinical effect, symptom improvement time, nursing quality score and satisfaction score between the two groups were compared and analyzed. The efficacy of the experimental group was significantly higher than that of the control group (p=0.02). After comprehensive nursing intervention, the cough disappearance time, body temperature recovery time, pulmonary rales disappearance time and hospitalization time in the experimental group were significantly shorter than those in the control group, with statistically significant differences (p<0.05). The scores of nursing quality such as health guidance, nursing operation, and medication management in the experimental group were higher than those in the control group, with significant differences in the data comparison between the groups (p<0.05). The satisfaction of the experimental group was 100%, which was higher than 90% of the control group, with a statistically significant difference (p=0.04). Comprehensive nursing intervention boasts various significant effects in the treatment of pediatric pneumonia, such as rapid amelioration of the condition, improvement of efficacy, and enhancement of nursing quality and satisfaction.

Study on the Application of the Concept of Childlike Interest with Refined Nursing Intervention in the Treatment of Children with Severe Pneumonia.

Objectives To analyze the application of childlike concept with refined nursing intervention in the treatment of children with severe pneumonia. Methods 100 cases of children with severe pneumonia admitted to our hospital from June 2019 to June 2021 were selected and divided into the control group and the observation group, in which the control group was given refined nursing care and the observation group was given the childlike concept with refined nursing intervention to compare the treatment effects of patients in both groups. The clinical indexes such as recovery time of body temperature, disappearance time of pulmonary rales, recovery time of heart rate, disappearance time of cough, and hospitalization time, were compared between the two groups. Results Compared with the control group, the time to recovery of body temperature, time to disappearance of pulmonary rales, time to recovery of heart rate, time to disappearance of cough, and hospitalization time were significantly lower in the observation group, and the difference was statistically significant (P < 0.05). Compared with the control group, the compliance rate of patients in the observation group was significantly lower, and the difference was statistically significant (P < 0.05). Compared with the control group, the total effective rate of patients in the observation group was significantly higher, and the difference was statistically significant (P < 0.05). Compared with the control group, the overall satisfaction rate of patients in the observation group was significantly higher, and the difference was statistically significant (P < 0.05). The results of univariate analysis showed that the differences between the two groups were statistically significant (P < 0.05) in terms of economic conditions, payment method, child's condition, child's age, comorbid underlying diseases, and nursing care method, and the results of logistic multifactor regression analysis showed that the payment method of self-payment, child's critical condition, and comorbid underlying diseases were the most important factors affecting the anxiety of the family members of children with severe pneumonia. risk factors for the occurrence of anxiety in the families of children with severe pneumonia, and the method of care was a protective factor (P < 0.05). Conclusion The concept of childlike fun and refined nursing interventions can effectively improve the treatment effect of children with severe pneumonia, improve patients' condition, increase patients' compliance and satisfaction, and reduce the risk of anxiety and other negative emotions of the child's family members.

Effects of Damage Control Resuscitation Combined with Alanyl Glutamine on Complications and Survival in Sufferers with Severe Multiple Trauma

To explore the clinical value of damage control resuscitation combined with alanyl glutamine in the treatment of severe multiple trauma sufferers is the main objective of the study. A total of 120 sufferers with injury severity score≥16 points of severe multiple trauma who were admitted to our hospital from November 2019 to February 2022 were selected and separated into blank group and intervention group (group J and group M) according to random grouping method with 40 people in each group. The general information, clinical indicators, thromboelastography indicators, complications and survival rate of the sufferers were recorded. The operation time, coagulation function time, hospitalization time, body temperature recovery time, prothrombin time, activated partial thromboplastin time, blood loss, total fluid input and mortality of the study subjects were statistically significant. The coagulation indexes of the three groups of research subjects before blood transfusion were not statistically significant and the coagulation indexes of the intervention group (J and M groups) after blood transfusion were statistically significant compared with the blank group. Damage control resuscitation combined with alanyl glutamine significantly reduces complication rates in sufferers with severe polytrauma, thereby improving the survival rate of sufferers after surgery.

Efficacy Analysis of Levofloxacin Combined with Cefoperazone/Sulbactam Sodium in the Treatment of Adult Bronchiectasis Complicated with Infection

Objective: To investigate the efficacy of levofloxacin combined with cefoperazone/ sulbactam sodium in the treatment of bronchiectasis complicated with infection in adults and its effect on lung function. Methods About 200 patients with bronchiectasis and infection from May 2019 to July 2022 in Jintan First People's Hospital of Changzhou City, Jiangsu Province were selected and divided into 2 groups (100 cases in each group) according to the treatment plan. The control group received cefoperazone /sulbactam sodium treatment, the observation group was treated with levofloxacin on the basis of the above. The evaluation was conducted by comparing the time of improvement of clinical symptoms, the decrease of inflammatory indicators, and the improvement of lung function indicators. Results After treatment, the overall effectiveness rate of the observation group was 93%, and the control group was 78%, which was significantly different (P<0.05), cough and sputum production, body temperature recovery and hemoptysis stop time were all earlier than those in the control group (P<0.05). Prior to treatment, there was no significant difference in neutrophil values (GRAN), white blood cell count (WBC), and hypersensitive C-reactive protein (CRP) between the two groups (P>0.05). After treatment, the GRAN, WBC and CRP of the control group were significantly higher than those in the observation group (P<0.05); there was no significant difference in forced expiratory volume (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC between the two groups before treatment (P>0.05), After treatment, the FVC, FEV1, FEV1/FVC values in the observation group were significantly higher than those in the control group (P<0.05). Conclusion The application of levofloxacin combined with cefoperazone/sulbactam sodium can effectively improve the clinical symptoms, inflammation level and pulmonary function indexes of adult bronchiectasis complicated with infection.

Clinical study on intravenous combined with aerosol inhalation of polymyxin B for the treatment of pneumonia caused by multidrug-resistant Gram-negative bacteria

To investigate the efficacy of intravenous combined with aerosol inhalation of polymyxin B for the treatment of pneumonia caused by multidrug-resistant Gram-negative (G-) bacteria. A observational study was conducted. The clinical data of 45 patients with pneumonia due to multidrug-resistant G- bacteria admitted to intensive care unit of Fujian Medical University Union Hospital from January to October in 2020 were analyzed. According to the different use methods of polymyxin B, 25 patients who received single intravenous drip (the first dose was 2.0 mg/kg, then 1.25 mg/kg, once every 12 hours) from January to April in 2020 were enrolled in the routine group, and 20 patients who received intravenous drip combined with aerosol inhalation (25 mg once every 12 hours, sputum in the airway was sucked and then sprayed aerosol) from May to October in 2020 were enrolled in the combination group. After the treatment course of polymyxin B, the total bacterial clearance rate, total clinical efficiency rate, recovery time of body temperature, time of bacterial clearance and the change of serum procalcitonin (PCT) level before and after treatment were compared between the two groups. Moreover, the incidence of adverse reactions during treatment in the two groups was observed. The results of sputum culture in the routine group were Acinetobacter baumannii in 13 patients, Klebsiella pneumoniae in 5 patients, Pseudomonas aeruginosa in 6 patients, Enterobacter cloacae in 1 patient; the sputum culture results of the combination group showed that there were 5 patients of Acinetobacter baumannii, 9 Klebsiella pneumoniae and 6 Pseudomonas aeruginosa. There was no significant difference in the results of sputum culture between the two groups (P > 0.05). The total bacterial clearance rate and the total clinical efficiency rate of the combination group were significantly higher than those in the routine group (total bacterial clearance rate: 70.0% vs. 40.0%, total clinical efficiency rate: 75.0% vs. 40.0%, both P < 0.05). The recovery time of body temperature and the time of bacterial clearance of the combination group were significantly shorter than those in the routine group [recovery time of body temperature (days): 6.0±3.9 vs. 10.2±7.3, time of bacterial clearance (days): 6.1±5.2 vs. 11.5±6.8, both P < 0.05]. No significant difference was found in serum PCT level before treatment between the two group. There was no significant difference in serum PCT level before and after treatment in the routine group [μg/L: 0.85 (0.44, 2.87) vs. 1.43 (0.76, 5.30), P > 0.05]. The serum PCT level after treatment in the combination group was significantly lower than that before treatment [μg/L: 0.27 (0.10, 0.70) vs. 0.91 (0.32, 3.53), P < 0.05], and it was significantly lower than that in the routine group [μg/L: 0.27 (0.10, 0.70) vs. 0.85 (0.44, 2.87), P < 0.01]. The incidence of renal toxicity of polymyxin B between the combination group and the routine group was not significantly different (5.0% vs. 4.0%, P > 0.05). The efficacy of intravenous combined with aerosol inhalation of polymyxin B for the treatment of pneumonia due to multidrug-resistant G- bacteria is better than that of intravenous drip of polymyxin B only. The aerosolized polymyxin B will not increase the risk of renal injury.

Cautionary findings for motor evoked potential monitoring in intracranial aneurysm surgery after a single administration of rocuronium to facilitate tracheal intubation.

Administration of rocuronium to facilitate intubation has traditionally been regarded as acceptable for intraoperative motor evoked potential (MEP) monitoring because of sufficiently rapid spontaneous neuromuscular blockade recovery. We hypothesized that residual neuromuscular blockade, in an amount that could hinder optimal neuromonitoring in patients undergoing intracranial aneurysm clipping, was still present at dural opening. We sought to identify how often this was occurring and to identify factors which may contribute to prolonged blockade. Records of 97 patients were retrospectively analyzed. Rocuronium was administered to facilitate intubation with no additional neuromuscular blockade given. Prolonged spontaneous recovery time to a train-of-four (TOF) ratio of 0.75 after rocuronium administration was defined as 120min, which was approximately when dural opening and the setting of baseline MEPs were occurring. Logistic regression analysis was used to identify factors related to prolonged spontaneous recovery time. Prolonged spontaneous recovery time to a TOF ratio of 0.75 was observed in 44.3% of patients. Multivariable analysis showed that only the dosage of rocuronium based on ideal body weight had a positive correlation with prolonged spontaneous recovery time (P = 0.01). There was no significant association between dosage of rocuronium based on total body weight, age, sex, or body temperature and prolonged recovery time. This study demonstrates that the duration of relaxation for MEP monitoring purposes is well-beyond the routinely recognized clinical duration of rocuronium. Residual neuromuscular blockade could result in lower amplitude MEP signals and/or lead to higher required MEP stimulus intensities which can both compromise monitoring sensitivity.

Randomized double-blind parallel controlled multicenter trial of Reyanning Mixture in treatment of acute tonsillitis

This study is a randomized controlled trial of Reyanning Mixture in the treatment of acute tonsillitis. According to the ratio of 1∶1∶1, a total of 144 patients were randomly divided into Reyanning Mixture group(RYN), Reyanning Mixture+Amoxicillin Capsules group(RYN+Amoxil) and Amoxicillin Capsules group(Amoxil), with 48 cases in each group, in order to evaluate the efficacy and safety of RYN alone or combined with Amoxil in the treatment of acute tonsillitis, and provided high-quality evidences for treatment of infectious diseases with traditional Chinese medicine and reduced use of antibiotics. The dosage of RYN was 20 mL, 3 times a day, 100 mL/bottle, oral for 7 days, and Amoxil dosage was 0.5 g, 3 times a day, 0.5 g×12 tablets/plate, oral for 7 days. A total of 144 cases were included, 3 cases were excluded(1 case was mistakenly included, 2 cases did not take drugs after inclu-ded), and a total of 141 cases were included in the full analysis set(FAS). The results showed statistical differences in the recovery time of the disease, the disappearance rate of fever on the 3 rd day and the disappearance rate of tonsillar redness and swelling between RYN and Amoxil. There were statistical differences in the cure rate of disease, recovery time of disease, body temperature recovery time, fever disappearance rate on the 3 rd day, pharynx swelling and pain disappearance rate and tonsil swelling disappearance rate between the RYN+Amoxil and Amoxil, but with no significant difference in the above aspects compared with RYN. The DDD of antibiotic use in RYN+Amoxil was significantly lower than that in Amoxil(P&lt;0.01). According to the findings, when RYN was used alone in the treatment of acute tonsillitis, it was superior to Amoxil in time of recovery, short-term improvement of fever and redness and swelling of tonsil. Compared with RYN+Amoxil, there was no difference in cure rate of disease, recovery time of disease, body temperature recovery time, short-term improvement of fever, swelling of pharynx and swelling of tonsil, with a better efficacy than Amoxil. The clinical effect of RYN was similar to that of combined Amoxil in the treatment of acute tonsillitis, and RYN was superior to Amoxil in the time of recovery, short-term improvement of fever and redness and swelling of tonsil, with no adverse event or adverse reaction. RYN+Amoxil can significantly reduce the DDD value of antibiotics in the treatment of acute tonsillitis, with significant clinical advantages over Amoxil.

Ameliorative effects of ceftriaxone sodium combined with dexamethasone on infantile purulent meningitis and associated effects on brain-derived neurotrophic factor levels.

The aim of the present study was to evaluate the role of ceftriaxone sodium combined with dexamethasone on the treatment of infant purulent meningitis (PM) and to measure brain-derived neurotrophic factor (BDNF) levels in children with PM. Of the 177 patients enrolled into the present study, 92 patients received ceftriaxone sodium+dexamethasone (combination group) and 85 patients received ceftriaxone sodium alone (monotherapy group). The time taken for the body temperature, peripheral blood (PB) and cerebrospinal fluid (CSF) white blood cell (WBC) counts to recover back to normal levels were compared between the two groups. In addition, changes in the CSF WBC counts, CSF protein and sugar concentrations, BDNF levels, effective treatment rates and incidence of adverse reactions three days before treatment (T1), after one week of treatment (T2) and after two weeks of treatment (T3) were compared between the two groups. In the combination group, the recovery time of body temperature, WBC counts in both PB and CSF were significantly lower compared with those in the monotherapy group. The combination group also exhibited lower CSF protein concentrations and higher CSF sugar concentrations at T2 and T3 compared with those in the monotherapy group (P<0.05). The effective treatment rate of the combination group was significantly higher compared with that of the monotherapy group (P=0.006). CSF protein at T1, T2 T3, and CSF sugar concentrations and BDNF levels at T1 were significantly lower in the combination group than in the monotherapy group (P<0.05) while the CSF sugar concentrations at T2, T3 were higher in the combination group than in the monotherapy group (P<0.05). Taken together, these observations suggest that ceftriaxone combined with dexamethasone was superior compared with that of ceftriaxone alone for the treatment of infantile PM, and that this combination therapy may improve the effective treatment rate and accelerate patient rehabilitation.

Effects of Maxing-Shigan decoction on inflammatory factors and immune function of children with mycoplasma pneumonia

Objective To investigate the effect of Maxing-Shigan decoction on inflammatory factors and immune function of mycoplasma pneumonia (MPP). Methods According to the random table method, 123 children with MPP who met the inclusion criteria were divided into control group (61 cases) and treatment group (62 cases). The control group was treated with azithromycin, while the treatment group was treated with Maxing-Shigan decoction on the basis of the control group. The treatment course was two weeks in two groups. The level of IL-2, IL-4, IL-6, TNF-α, CRP and CD3+, CD4+, CD8+ and CD4+/CD8+ was detected by ELISA. The recovery time of body temperature, the fading time of coughing, the fading time of crackles and rale and the time of hospitalization was observed, TCM symptoms and signs was also scored, and the clinical efficacy was evaluated. Results The total effective rate was 90.3% (56/62) in the treatment group and 73.8% (45/61) in the control group. There was significant difference between the two groups (χ2=5.736, P=0.017). The recovery time of body temperature, the fading time of coughing, the fading time of crackles and rale and the time of hospitalization in the treatment group was significantly lower than those in the control group (t=-6.969, -5.700, -8.226, -7.034, P<0.01). Compared with the control group after treatment, the serum level of IL-2 significantly increased, IL-4, IL-6, TNF-α and CRP significantly decreased in the treatment group (t=12.729, -6.373, -6.416, -14.482, -20.071, P<0.01), while the serum level of CD3+, CD4+, CD4+/CD8+ significantly increased and CD8+ significantly decreased in the treatment group (t=2.314, 2.556, -3.866, 11.226, P<0.05). Conclusions The Maxing-Shigan decoction treats MPP by improving inflammatory factors and immune function, which not only improve the clinical symptoms, but also has high safety. It is worth promoting the application in clinic. Key words: Ma Xing Shi Gan Tang; Pneumonia, mycoplasma; Immunity; Inflammatory factors

Mixture prepared with Chinese medicines in terms of releasing exterior cold and clearing interior heat: its efficacy and safety in patients with seasonal influenza-a randomized controlled trial

OBJECTIVETo assess the efficacy and safety in 105 patients with seasonal Influenza in Beijing, the mixture prepared with Chinese medicines follows the treatment regimen of releasing exterior cold and clearing interior heat. METHODSTotal 330 patients with seasonal influenza were enrolled and randomly and averagely divided into the Chinese herbal medicine, the western medicine and the Chinese patent medicine group. They were treated with Chinese medicine Oseltamivir Phosphate Capsules and the Scattering Wind and Resolving Toxins Capsules. The main efficacy indicators were the antifebrile onset time and recovery time of body temperature. The efficacy and safety of the mixture was scientifically evaluated. Comparisons of several variables were analyzed. RESULTSMedian antifebrile onset time of the Chinese herbal medicine group was significantly shorter than the western medicine group (P < 0.05) and the Chinese patent medicine group (P < 0.05). The median antifebrile recovery time of the Chinese herbal medicine group was significantly shorter than the Chinese patent medicine group (P < 0.05). The groups evaluated by TCM symptom pattern effect, both the Chinese herbal medicine group and Western Medicine group were better than the Chinese patent medicine group (P < 0.05). The disappearance rate of main symptoms and some minor symptom patterns of the Chinese herbal medicine group were higher than the other 2 groups. CONCLUSIONThe mixture of releasing exterior cold and clearing interior heat could significantly shorten the fever time with safety.

Jinye Baidu granule for wind-warmth lung-heat disease (heat in the lung-wei): protocol for a randomized, double-blind, parallel, controlled trial

ObjectiveTo observe the curative effect of Jinye Baidu granule in the treatment of fever and swollen and sore throat caused by wind-warmth lung-heat disease (heat in the lung-wei) to further identify the indications. MethodsThis randomized, double-blind, parallel, controlled trial will include patients with acute upper respiratory infection and wind-warmth lung-heat disease (heat in the lung-wei). Patients with serious bacterial infection (white blood cell count > 12 × 109, neutrophils > 80%) will be excluded. Patients will be divided into three categories (blocks) according to their condition: fever only, a swollen and sore throat, and combined fever plus a swollen and sore throat. Patients within each of the three blocks will be further divided into a treatment group and a control group via stratified blocked randomization. The treatment group will be treated with Jinye Baidu granule, and the control group will be treated with Fufang Shuanghua granule. The primary outcome measure will be body temperature recovery time for patients with fever, throat symptom score for patients with a swollen and sore throat, and body temperature recovery time and throat symptom score for patients with combined fever plus a swollen and sore throat. Routine blood testing, urine testing, liver function, kidney function and ECG data of all patients will be collected as safety indices before and after enrollment, and adverse events will be recorded during the whole trial course. ConclusionThis study protocol will include stratified block analysis according to patients' symptoms, and identify the accurate clinical indications of Jinye Baidu granule. It will also enable safety evaluation from laboratory indices and adverse events, which will provide reliable evidence for clinical treatment.

Study of Jinye Baidu granule in treatment of wind-warmth lung heat disease (heat in lung-wei pattern)： a randomized, double-blind, parallel-controlled trial

A randomized, double-blind, active parallel controlled trial will be conducted to include patients with acute upper respiratory infection and wind-warmth lung heat disease (heat in lung-wei pattern). Patients with serious bacterial infection (white blood cell count>1.2×1010, neutrophil>80%) will be excluded.so as to further identify Jinye Baidu Granule indications of Wind-warmth lung heat disease (heat in lung-wei pattern).According to the subjects of symptoms of fever and sore throats,Patients will be divided into three blocks： fever, swelling and sore throat, combined fever and swelling and sore throat. Subjects in three blocks will be divided into treatment group and control group with stratified blocked randomization. The treatment group will be treated with Jinye Baidu Granule, and the control group will be treated with Fufang Shuanghua granule. Primary outcome measure of patients with fever will be body temperature recovery time. Primary outcome measure of patients with swelling and sore throat will be throat symptom score. Primary outcome measures of patients combined with fever and swelling and sore throat will be body temperature recovery time and throat symptom score. Before and after all of the patients in the group were collected blood and urine routine, liver and renal function, electrocardiogram (ECG) data as the safety index while observing it adverse events. A total of 623 patients were included. Compared with control group,sore throat symptoms of patients with sore throat and pharyngeal symptoms total score have significantly different. so Jinny Baidu granule have a significant advantage in the treatment of sore throat. All of the experiments showed that the safety of the drug was good. Nausea, vomiting, stomach pain, diarrhea, digestive tract symptoms may occur only occasionally. We should pay attention to the changes when using in patients with spleen deficiency cold to avoid adverse reaction.

The application experience of all-around nursing care in infantile febrile convulsion.

The aim of this study was to analyze the value of all-around nursing care for infantile febrile convulsion. Ninety-eight cases diagnosed with infantile febrile convulsion from February 2013 to October 2014 were selected to participate in this study. This study was approved by the hospital's ethics committee and received consent from the patients as well as their families. The patients were divided into a control group (N.=48 cases) and an observation group (N.=50 cases). Patients in both groups were offered anticonvulsants. The control group was offered general nursing care while the observation group was offered all-around nursing care. We compared and analyzed the nursing care in both groups. The body temperature recovery and convulsion control time in the observation group were lower than the control group. Remarkably, the convulsion control rate was higher than the control group. The hospital stays were lower in the observation group compared to the control group (P<0.05). The patients' serum potassium, serum sodium levels and blood glucose before nursing care were all in the normal range. However, the serum potassium and serum sodium levels in the control group were lower, and the blood glucose level was higher than previous. After nursing care, the serum potassium and serum sodium levels in the observation group were higher than the control group. The blood glucose level was lower than the control group (P<0.05). The nursing satisfaction in the observation group was higher than the control group. The convulsion recurrence rate was lower in the observation group compared to the control group (P<0.05). The combination of all-around nursing care and anticonvulsants can improve the occurrence and duration of infantile febrile convulsion.

Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis

Objective To evaluate the clinical effect of buccal administration of Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis. Method A total of 103 infantiles with herpetic stomatitis were randomly divided into a Kangfuxin group (51 cases) and a conventional group (52 cases). The conventional group received ribavirin aerosol, and the Kangfuxin group recived buccal administration of Kangfuxin Liquid based on the intervention of convertional group. All children were treated for 5 days. The white blood cell count (WBC) and the serum C-reactive protein (CRP) were determined. Result The total efficiency rate in the Kangfuxin group was significantly higher than that in the conventional group (94.1% vs. 78.8%, χ2=3.895, P<0.05). The healing time of oral ulcers (5.8 ± 1.3 d vs. 7.9 ± 1.5 d, t=10.715), body temperature recovery time (2.1 ± 1.1 d vs. 3.3 ± 1.5 d, t=4.623), and eliminating time of oral mucosal hyperemia and edema (4.3 ± 1.3 d vs. 5.3 ± 1.4 d, t=3.755) in the Kangfuxin group was significantly shorter than those in the conventional treatment group (P<0.01). The WBC (6.5×109 ± 2.2×109/L vs. 9.4×109 ± 2.3×109/L, t=6.537) and serum CRP levels (6.7 ± 1.2 mg/L vs. 9.7 ± 2.5 mg/L, t=12.686) were significantly lower in the Kangfuxin group was significantly lower than those in the conventional treatment group (P<0.01). Conclusions The total efficiency rate of buccal administration of Kangfuxin Liquid combined with conventional treatment for infantile herpetic stomatitis was higher than conventional treatment alone. And the remission time of symptoms of treatment group was shorter. Key words: Stomatitis, herpetic; Child, preschool; Ribavirin; Integrated Chinese traditional and western medicine therapy; Treatment outcome; Kangfuxin Liquid

Effect observation of gastrointestinal nutrition therapy on patients with neonatal scle-redema and nursing experience

Objective To study effect of gastrointestinal nutrition therapy on patients with neonatal scleredema and nursing methods. Methods A total of 70 patients with neonatal scleredema were selected and divided into control group(31 cases)and observation group(39 cases). The control group adopted the routine nursing, based on the control group gastrointestinal nutrition therapy was used in the observation group. Treatment time and treatment effect were compared between groups. Results In the observation group patients'body temperature recovery time, scleredema disappearing time, the length of hospitalization time were significantly shorter than those in the control group. Healing and efficient were significantly higher than those in the control group. The differences were statistically significant with comparison between the two groups(P<0.05). Conclusions The implementation of gastrointestinal nutrition therapy on patients with neonatal scleredema is safe and effective and has important significance in clinic. Key words: Neonatal scleredema; Gastrointestinal nutrition therapy; Nursing; Effect

Clinical observation on the montelukast sodium combined with azithromycin treament for mycoplasma pneumonia in children

Objective To investigate the clinical effect of montelukast sodium combined with the azithromycin treatment of mycoplasma pneumonia(MP).Methods 82 cases of MP children were randomly divided into observation group and control group,41 cases in each group,the control group was treated by the azithromycin on the basis of the conventional treatment,the observation group was treated by montelukast sodium on the basis of the treatment for control group,and then compared the children' s body temperature recovery time.cough disappeared time,wheezing disappeared time,and the asthma follow-up occurred within 6 months between the tw0 groups.Results The body temperature recovery time of the observation group and the control group were (3.8 ± 1.1) d and (3.5 ± 1.5) d respectively,the differences were not statistically significant between the two groups (P＞0.05).The coughing and wheezing disappeared time in the observation group and the control groupwere( 21.4 ± 3.4 ) d,(8.1 ± 2.5) d and( 8.1 ± 1.7) d,( 6.0 ± 1.5 ) d,the difFerences were statistically significant between the two groups ( P＜0.05 ).Disease incidence of the mycoplasma pneumomae infection secondary to asthma in the observation group and the control group were 39.02% and 9.76%.the differences were statistically significant between the two groups ( P＜O.01 ).One case of suspected adverse reactions associated with montelukast sodium in the observation group.the incidence of 2.44%.expressed as rash,without spontaneous remission after discontinuation.There were no other significant adverse reactions occurred.Conclusion Montelukast sodium azithromycin treatment for children with MP has better clinical effects,not only can significantly improve the clinical symptoms and signs of the children,but also can reduce the recurrence rate,with fewer complications,which is worthy of clinical application. Key words: Mycoplasma pneumonia; Pediatric; Montelukast sodium; Azithromycin

Experiences on external fixation - the line of damage control orthopedic therapy in the repair of trauma

Objective To investigate the application and effects of external fixator-damage control therapy in rehabilitation of orthopedic trauma.Methods 45 cases with severe pelvic fracture were given damage control therapy as observation group. Other 45 patients were selected as control without being given damage control therapy. In the observation group, external fixation was firstly used, and then, after conditions being stable, second stage open reduction treatment was also conducted. As for the patients in control group, only the first stage open reduction was carried out.Results Among the observation group,39 patients survived, 6 died. 30 patients survived and 15 cases died in the control group. The intraoperative blood loss, surgery time, recovery time of the body temperature, lactic acid clearance time, PT / APTT recovery time in observation group were significantly less than those of the control group (P＜0.05). Conclusion The curative effects of damage control treatment are obvious with good prognosis, and worth being used popularly. Key words: External fixation; Damage control treatment

The applications of vaginal hysterectomy of non-prolapsed uterus lesion in primary hospital

Objective To explore the application value and techniques of vaginal hysterectomy of non-prolapsed uterus lesion in primary hospital. Methods 140 cases who suffered from uterine fibroid without adhesion,glandular fibroids,functional bleeding without uterine prolapse and malignant disease were selected and divided into observation group(80 cases with vaginal hysterectomy)and control group(60 cases with routine abdominal hysterectomy).Then the clinical treatment effect was analyzed. Results Compared with control group,peri-operative bleeding (150 ±23)ml vs(243 ±41)ml,operation time(65 ± 14.0)min vs(90 ± 27.0)min,body temperature recovery time (3 ±0.5)d vs(4 ±0.8)d,anus exhaust time(14 ± 1.8)h vs(26 ±2.7)h,the length of time(5 ±0.8)d vs(11 ±2.9)d in observation group were all reduced,differences were significant(all P＜0.01)and no case was transferred to opening appendectomy. Conclusion For these disease including uterine fibroids with no adhesion,glandular fibroid uterine bleeding,the vaginal hysterectomy was safe and feasible,and had the advantage of smaller trauma,less bleeding,shorter hospitalization time,faster recovery etc.It was worthy to be popularized in primary hospital. Key words: Non-prolapsed uterus; Hysterectomy