Abstract
Objective To investigate the clinical effect of montelukast sodium combined with the azithromycin treatment of mycoplasma pneumonia(MP).Methods 82 cases of MP children were randomly divided into observation group and control group,41 cases in each group,the control group was treated by the azithromycin on the basis of the conventional treatment,the observation group was treated by montelukast sodium on the basis of the treatment for control group,and then compared the children' s body temperature recovery time.cough disappeared time,wheezing disappeared time,and the asthma follow-up occurred within 6 months between the tw0 groups.Results The body temperature recovery time of the observation group and the control group were (3.8 ± 1.1) d and (3.5 ± 1.5) d respectively,the differences were not statistically significant between the two groups (P＞0.05).The coughing and wheezing disappeared time in the observation group and the control groupwere( 21.4 ± 3.4 ) d,(8.1 ± 2.5) d and( 8.1 ± 1.7) d,( 6.0 ± 1.5 ) d,the difFerences were statistically significant between the two groups ( P＜0.05 ).Disease incidence of the mycoplasma pneumomae infection secondary to asthma in the observation group and the control group were 39.02% and 9.76%.the differences were statistically significant between the two groups ( P＜O.01 ).One case of suspected adverse reactions associated with montelukast sodium in the observation group.the incidence of 2.44%.expressed as rash,without spontaneous remission after discontinuation.There were no other significant adverse reactions occurred.Conclusion Montelukast sodium azithromycin treatment for children with MP has better clinical effects,not only can significantly improve the clinical symptoms and signs of the children,but also can reduce the recurrence rate,with fewer complications,which is worthy of clinical application. Key words: Mycoplasma pneumonia; Pediatric; Montelukast sodium; Azithromycin
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