Blood Pressure In Experimental Group Research Articles

PS-C20-3: MOBILE MEDICAL APP CAN BE MORE EFFECTIVE IN LONG-TERM MANAGEMENT OF HYPERTENSION PATIENTS

Objective: The application of mobile medical application, APP, to manage patients with hypertension makes the contact between doctors and patients more convenient, saves the economic cost and time cost of patients, and also makes it easier for doctors to manage patients and improve their compliance. This study investigated the effect of APP on long-term management of hypertension patients. Design and method: This trial was a randomized, single-blind, parallel, controlled study. A total of 302 patients with hypertension were included in this study and observed for one year. All the enrolled patients received antihypertensive treatment of nifedipine controlled release tablets with or without telmisartan in outpatient or ward. The APP of the experimental group could be used to push health education information, remind patients to measure their own blood pressure and take medication, and consult doctors online. Blood pressure, improvement of hypertensive target organ injury, and sodium intake were assessed in both groups after one year treatment. Results: There were no significant differences in blood pressure, urinary microalbumin and 24-hour urinary sodium levels between the two groups at baseline. APP information push was more helpful to the control of blood pressure, systolic and diastolic blood pressure decreased significantly, after treatment, systolic blood pressure of experimental group vs control group 133 ± 6mmHg vs 141 ± 11mmHg, P < 0.05; Diastolic pressure 83 ± 7mmHg vs 89 ± 9mmHg, P < 0.05. APP information push was more helpful to improve target organ injury (decrease of microalbuminuria), and microalbuminuria after treatment was 31 ± 12 mg/L vs 47 ± 14 mg/L, P < 0.05. APP information push helped control sodium intake, and the urine sodium level at 24 hours after treatment was 123 ± 31 mmol/24 h vs 148 ± 28 mmol/24 h, P < 0.05. Conclusions: Using mobile medical APP for patient management can help control patients’ blood pressure level, improve the degree of renal damage caused by hypertension, and help control sodium intake. APP can be used as an auxiliary means for long-term management of hypertension patients, which can improve the quality of blood pressure management of patients more effectively, conveniently and economically.

Calcium supplementation from chicken eggshells to increase nitric oxide levels and control blood pressure in gestational hypertension

Background: Hypertension is one of the highest causes of death in pregnant women. Calcium deficiency can lead to hypertension. Chicken eggshell can be used as a natural calcium supplementation therapy in hypertension.Purpose: Analyze the effect of chicken eggshell on blood pressure through the increased nitric oxide level in gestational hypertension.Methods: This is Quasy experiment research with pretest and posttest with control group design. Respondents were ≥20 weeks pregnant women with gestational hypertension. Determination of respondents by purposive sampling obtained experimental group (n=12) and control group (n=12). 1.1 g/day of eggshell flour was given for 14 days.Result: Mean of systolic and diastolic blood pressure in experimental group decreased 14.25 mmHg or 9.5% (p=0.000) and 12.84 mmHg or 13.04% (p=0.000) after received chicken eggshell flour for 14 days compared to control group mean of systolic and diastolic blood pressure increased 1.92 mmHg or 1.35% (p=0.000) and 0.33 mmHg or 0,34% (p=0.121). Nitrit oxide level of experimental group increased 8.250 μmol/L or 20.93% (p=0.020) and control group decreased 3.083 μmol/L or 7.20% (p=0.488).Conclusion: Chicken eggshell flour affects increasing nitric oxide levels and controls systolic and diastolic blood pressure in gestational hypertension.

A QUASI-EXPERIMENTAL PRE-TEST-POST TEST GROUP DESIGN TO ASSESS THE EFFECTIVENESS OF JACOBSON’S PROGRESSIVE MUSCLE RELAXATION EXERCISE ON BLOOD PRESSURE AMONG PATIENT WITH HYPERTENSION IN SACRED HEART HOSPITAL AT THOOTHUKUDI

The objectives of the study were to 1. determine the pre-test and post-test level of blood pressure among patients with Hypertension in experimental and control group.2. assess the efficacy of Jacobson’s progressive muscle relaxation exercise on blood pressure among patients with Hypertension in experimental group.3. Associate the selected socio demographic variables with the level of blood pressure in experimental group. Hypothesis H0: There will not be a significant difference between pre and post test level of blood pressure after Jacobson’s progressive muscle relaxation exercise among patient with Hypertension in experimental and control group. H1: There will be a significant decrease in the level of blood pressure after Jacobson’s progressive muscle relaxation exercise among patient with Hypertension in experimental group. H2:There will be significant association between post test levels of blood pressure with selected demographic variables in experimental group. H01: There will not be significant association between post test levels of blood pressure with selected demographic variables in experimental group. Review of literature was organised based on review related to Jacobson’s progressive muscle relaxation and Jacobson’s progressive muscle relaxation on blood pressure. The tool was validated by experts and found to be valid for the study. Sampling Technique: Sample was selected by using non probability convenience sampling method. Results: the data was tabulated, analyzed and interpreted by using descriptive and inferential statistics. After the detailed analysis this study leads to following conclusions, longer day of intervention shows significant decrease in the level of blood pressure. Major findings show that there is significant decrease in the level of blood pressure after Jacobson’s progressive muscle relaxation exercise among patient with Hypertension in experimental group. It was statistically significant at (P<0.001). Hence the sta

Effectiveness of Foot Bath Therapy in Reducing Blood Pressure among Clients with Hypertension

A quasi experimental study was conducted to assess the effectiveness of footbath therapy in reducing blood pressure among clients with hypertension at selected hospital among 60 clients who satisfy inclusive criteria were selected as samples using purposive sampling technique. Foot bath therapy was given for 10 minutes twice a day. The pre and post level of blood pressure was measured using sphygmomanometer. The findings revealed that there was a high statistical difference in the level of blood pressure. The pretest mean level of BP was 141.3, standard deviation is 10.24 and the post test mean is 126.3, standard deviation is 7.06, ‘t’ test value is 32.67 in experimental group. In control group, the pretest mean level of BP was 155, standard deviation is 16.27 and the post test mean is 145.6, standard deviation is 16.26, ‘t’ test value is 6.22. The study concluded that there was significant reduction in Blood Pressure in experimental group as compared to the control group. This shows that foot bath technique is effective in hypertensive clients.

ASSA13-14-2 The Influence of Long-Term Regular Vitamin D Intervention to Renin and Renin Receptor in Spontaneously Hypertensive Rats

Objective To explore the influence of long-term regular vitamin D intervention on rennin and its receptor in spontaneously hypertensive rats. Methods 20 spontaneously hypertensive rats were randomly divided into two groups. The experimental group received vitamin D3 preparation 3ug/kg dissolved in 0.5ml propylene glycol by intraperitoneal injection (twice a week) for three months; the control group was given the equal volume of propylene glycol alone. Monitor the changes of blood pressure of rats during the experiment every week. Serum was collected after the experiment. Serum 25(OH)D3, calcium, rennin concentration were detected by Enzyme-linked immunosorbent. To explore renin and renin receptor mRNA expression levels in kidney between the two groups by RT-PCR. Renin receptor’s expression in kidney and heart was examined by immunohistochemical and computer image analysis. Pathological change was examined by HE staining. Results The blood pressure of experimental group was lower than that in control group ( P P P P P > 0.05). It found that renin receptor was widely distributed by Immunohistochemical, but there was no difference in the two groups ( P > 0.05). HE staining displayed there was hypertensive pathological changes in control group, but it was not obvious in the experimental group. Conclusions vitamin D can inhibit renin gene transcription, inhibit hypertensive organ damage, but its effect to renin receptor is not obvious.

Effect of supplementation of tender coconut water on blood pressure of primary hypertensive subjects

Background: Hypertension is a major health problem worldwide. Increased vascular resistance, sodium retention & sympathetic over activity contributes to the blood pressure elevation. Plant foods may be beneficial in decreasing blood pressure (BP). Recently much attention has been focused on plant foods that may be beneficial in preventing Hypertension, metabolic syndrome and possibly reduce the risk of various diseases. This clinical study was conducted to test the effectiveness of a structured intervention on BP of primary hypertensive subjects. Aim: To study the effect of Tender Coconut Water (TCW) on BP of Primary hypertensive subjects. Methods and Material: 70 subjects were selected randomly sample for 6 weeks of the intervention program. Among them 40 subjects were selected as the experimental group and 30 300ml/day for 6 weeks whereas the control group was instructed to follow the same routine without modifications. One initial, two mid intervention (after every 15 days) and one final (post intervention) BP recorded for both the groups. The obtained data was statistically analyzed. Results: The mean systolic BP of experimental group and control group were decreased from 145.8 mm Hg and 141mm of Hg to 135.3 mm of Hg and 140 mm of Hg respectively. The mean diastolic BP of experimental group and control group were decreased from 93.7 mm H g and 90.9 mmHg to 86.9 mm of Hg and 89.7 mm of Hg respectively. Conclusion: Irrespective of cause of hypertension TCW has beneficial effect on BP. TCW contains high amount of potassium which causes vasodilatation and also improve the endothelial function.

Effects of N-acetyl cysteine on serum lipoprotein (a) and proteinuria in type 2 diabetic patients

About 30-40% of diabetic patients who developed nephropathy have lipoprotein disorders, especially lipoprotein a [Lp(a)], which is related to atherosclerosis. The aim of this study was to investigate the effect of N-acetyl cysteine (NAC) on the serum levels of Lp(a) and amount of proteinuria in a group of type 2 diabetic patients with diabetic nephropathy. A total of 40, type 2 diabetic (T2D) patients, patients with proteinuria, were randomly divided into two groups. The experimental group was treated by NAC (1200 mg/day) for two months in conjunction with conventional treatment for diabetes and hypertension. Control group received routine medications. No significant change was identified in serum Lp(a) during treatment with NAC (P >0.05). However, NAC decreased the amount of proteinuria, serum triglyceride (TG) level and systolic blood pressure in experimental group compared to the control group (P <0.05). These findings suggest that treatment with NAC has no significant effect on the serum level of Lp (a). However, it has beneficial effects on the reduction of proteinuria, serum TG level and systolic blood pressure in T2D patients with nephropathy. Further prospective studies are needed to determine its full role.

Effect of comprehensive nursing intervention on the treatment effect of common bile duct stones in patients undergoing endoscopy

Objective To investigate the effect of comprehensive nursing intervention on the treatment of common bile duct stones undergoing endoscopy. Methods A total of 137 patients with common bile duct stones undergoing the endoscopic treatment were randomly divided into intervention group （ n = 69 cases） and control group （ n = 68 patients）. All the patients received routine care before and after the endoscopic treatment. In addition, the patients in the intervention group received audio-visual training intervention with preoperative, music therapy with intra-operative and position training intervention with postoperative. The intervention effect was compared between the two groups. Results Breath rate, heart rate, oxygen saturation before treatment were not different in the two groups （ P 〉 0. 05 ）. Breath frequency in intervention group after treatment was （ 23.6±3.4）time/rain, the first bed time was （19.24±3.67）h, extubation rate was 97. 10% and complication rate was 4.35% and those in control group were （28.9±3.7） time/min, （24.62±4.81 ） h, 86.76% and 16.18% respectively, and the differences were significant （ t = 8.72, 7.35 ; X^2 = 4.96, 5.03 ; P 〈 0. 05 ）. Heart rate, blood pressure in experimental group after treatment were reduced and the extubation time and in hospital time were shorten than control group, however, the sleeping time was longer in experimental group （ P 〈 0. 05 ）. Conclusions Comprehensive nursing intervention can improve treatment compliance, promote patients＇ early recovery and achieve the desired effect. Key words: Common bile duct stones; Endoscopy therapy; Comprehensive nursing intervention

The effects of an integrated health education and exercise program in community-dwelling older adults with hypertension: A randomized controlled trial

Objective The aim of this study was to examine the effectiveness of HAHA (Healthy Aging and Happy Aging) program, which is an integrated health education and exercise program for community-dwelling older adults with hypertension. Methods: Older adults with hypertension from one senior center were randomly allocated to experimental ( n = 18) or control group ( n = 22). Experimental group received health education, individual counseling and tailored exercise program for 12 weeks. Results: The mean ages were 71 years (experimental group) and 69 (control group). After the intervention, systolic blood pressure of experimental group was significantly decreased than that of control group. Scores of exercise self-efficacy, general health, vitality, social functioning, and mental health in SF-36 were statistically higher than those of control group. Conclusion: The HAHA program was effective in control of systolic blood pressure and improving self-efficacy for exercise and health-related quality of life.

Study on Evidence-based nursing is applied in improving quality of life of college teachers who are suffering high blood pressure

Objective To explore the role of the evidence-based nursing in improving the quality of life of hypertension patients of college teachers, in order to provide the basis for nursing intervention model. Methods The annual physical examination 60 patients with hypertension of teachers were randomly divided into 30 cases of the experimental group and 30 cases of control group. The experimental group was used evidence-based care,and the control group was used conventional care. Before and after nursing intervention the blood pressure was measured and the application of SF-36 (36-item Short Form Health Survey, SF-36) Health Survey Scale evaluate the quality of life of two groups of patients. Results The decline of blood pressure in experimental group was better than the control group, and the quality of life indicators scored was significantly higher than the control group,( P< 0.05 ) that evidences the patients' quality of life is better than the control group, conclusions The use of evidence-based nursing can effectively improve the quality of life of college teachers hypertension. Key words: Evidence-based care; College teachers; Hypertension; Quality of life