Piezoelectric actuators are widely utilized to convert electrical energy into mechanical strain with considerable potential in micro mobile robot applications. However, the use of Pb-based Lanthanumdoped Zirconate Titanates (PZTs) leads to two difficulties in drive circuit design, namely, high voltage step-up ratio and high energy conversion efficiency. When some devices driven by piezoelectric actuators are used in emerging technologies, such as micro mobile robot, to perform special tasks, low mass, high energy density, and high conversion efficiency are strategically important. When these demands are considered, conventional drive circuits exhibit the disadvantages of being too bulky and inefficient for low mass applications. To overcome the aforementioned drawbacks, and to address the need for a piezoelectric bimorph actuator, this work proposed a high step-up ratio flyback converter cascaded with a bidirectional half-bridge stage controlled, via a pulse width modulation strategy, and a novel control method. Simulations and experiments were conducted to verify the ability of the proposed converter to drive a 100 V-input piezoelectric bimorph actuator using a prototype 108 mg (excluding printed circuit board mass), 169 (13 × 13) mm2, and 500 mW converter.