This paper presents the design and implementation of signed-unsigned Modified Booth Encoding (SUMBE) multiplier. The present Modified Booth Encoding (MBE) multiplier and the Baugh-Wooley multiplier perform multiplication operation on signed numbers only. Therefore, this paper presents the design and implementation of SUMBE multiplier. The modified Booth Encoder circuit generates half the partial products in parallel. By extending sign bit of the operands and generating an additional partial product the SUMBE multiplier is obtained. The Carry Save Adder (CSA) tree and the final Carry Look ahead (CLA) adder used to speed up the multiplier operation. Since signed and unsigned multiplication operation is performed by the same multiplier unit the required hardware and the chip area reduces and this in turn reduces power dissipation and cost of a system. The proposed radix-2 modified Booth algorithm MAC with SPST gives a factor of 5 less delay and 7% less power consumption as compared to array MAC.