Basic Quality Research Articles

PROBLEMS OF ECOLOGIZATION OF AGRICULTURAL PRODUCTION AND FIGHT ARE AGAINST CHANGES OF CLIMATE IN CONTEXT OF DEVELOPMENT OF «GREEN» ECONOMY

The article examines environmentalization as continuous introduction of new technique and technologies for a production and modern forms of organization of labour. Introduction of new principles in to the system of the balanced development of Ukraine are basic tasks that is sent to provide of ecological constituent of industries of economy. It is marked that on the whole in a public policy tasks stand about reduction to the booty of natural resources for the use in a national economy, reduction of accumulation of contaminating wastes at the production of different types of products and separately each and general production on the whole. It is marked that an ecologization of industries of economy is an important constituent in their competitiveness and to compatibility with the basic terms of rational of nature management. Certainly, that beginning of ecologization of productive process is potential of increase of production volumes, where maintenance is and comes true passing to the speed-up increase of quality indexes of environmental preservation. It is marked the result of it, that in resource return come forward as basic quality ecological and economic indexes, ecological efficiency of economy, ecologization, ecofriendlyness, that in the future will become a base during realization of certain chart of management of operations. Essence of ecologization is considered from positions of the small and scale understanding. It is distinguished, that to the in the first case the ecologization – it is development and introduction of principles in relation to technical replacement; substituting by new technologies and organizations of labour, as a result they show up in the reduction of contamination of environment or in his renewal. In second case the ecologization – it is changes in a technique, to productive technology and in a production, that diminish the expenses of resources of natural environment in a count on unit of mine-out products or rendered service of corresponding quality. It is educed that as definition «ecologization» has changed in time and in accordance with the stages of ecologization in the context of world development. Materials of conferences of steady development are considered United Nations are on questions an environment. Materials of conference of the UNO are analyzed on questions the change of climate, where during two weeks discussed further steps for limitation of raising of middle global temperature within the framework of the Parisian agreement. It is indicated that at participating of Ukraine in a conference it was announced establishment of two initiatives: the Global platform for the estimation of losses to the environment and climate on that wars and initiatives influence in relation to creation of the «Green grain-growing corridors». The brought possible amount over of extrass of greenhouse gases, that get in an atmosphere in the consequence of an increase amount of fires through the conduct of battle actions and moving of people in the safe regions of country. The brought possible amount over of extras of greenhouse gases as a result of battle actions, that take place as a result of an increase amount of fires and moving of people in the safe regions of the country.

Comparative standardization studies of marketed Polyherbal tablets

Siddha and Ayurvedha is one of the oldest traditional systems of medicine in the world. There are different formulations which are adequately increase delivery of the drug to our body sites; one of basic formulation is tablet. Tablet is one of the conventional formulations in solid oral dosage form, which are usually used in traditional system of medicines and allopathic medicines. Allopathic formulations like tablets usually maintaining their standards based on the various pharmacopoeia but Ayurvedhic and Siddha proprietary medicines shows lots of troubles in their standardization parameters, why because they consist of multiple herbal crude drugs in one formulation, so it should be prescribed with proper standardization parameters. The present work deals with to evaluation two marketed formulation by performing basic quality control parameters of tablets such as Organoleptic properties, Weight variation, Hardness, Friability, Disintegration of herbal tablets {Alsactil [A] and Alsarex [B]} From the analysis of above parameters, results was observed and all the parameters of both drugs passes the test, within the reference values.

ТРЕНДЫ ИННОВАЦИОННОЙ СЕРВИСНОЙ СИСТЕМЫ ПРЕДПРИЯТИЙ ИНДУСТРИИ ГОСТЕПРИИМСТВА В КОНТЕКСТЕ ДИВЕРГЕНТНОГО СЕРВИСА

The introduction of the concept of divergent service into the organizational and service process of hospitality industry enterprises, including sanatorium-resort complexes, is based on the basic trends of the hospitality industry, this is the study of consumer behavior and their recreational needs; the formation of a team of specialists with a creative focus for the organization of innovative service programs using recreational technologies and divergent approaches; the creation of conditions in parts of the design of the spatial environment to create points of attraction, atmospherics in symbiosis with a set of additional services, both service and medical. Divergent thinking determines the creative way of development – the matrix construction of organizational culture, convergent thinking determines the constructive way of development – the hierarchical construction of organizational culture. The conceptual approach in the organization of service processes will allow to differentially increase the index of customer satisfaction, as well as to navigate modern trends in the field of health tourism. The importance of assessing the real situation of the quality of service lies in the analysis of basic quality assessment tools and system monitoring of customer satisfaction, finding the most suitable divergent approaches to solving service tasks for a specific hospitality enterprise. Hospitality industry enterprises use traditional management and quality control systems in their organizational culture – a convergent approach. In the case of the divergent approach, it is used quite rarely, due to the fact that the management staff is not yet ready to embark on innovative tracks, this is caused by several factors: - risks associated with unreasonable financial costs; - lack of a creative team capable of solving current problems; - fear of moving away from the traditional management system, control and remuneration system; - weak motivation for professional growth and the difficulty of getting out of the template of the mental matrix of promotion and sales of sanatorium and resort products. The conceptual solution of the implementation of the divergent service program in the conditions of the sanatorium-resort complex, as shown by the practice of testing programs with an individual trajectory of recreation, has a fairly high rating from the point of view of consumers.

A signal quality assessment method for fetal QRS complexes detection.

Non-invasive fetal ECG (NI-FECG) provides a non-invasive method to monitor the health of the fetus. However, the NI-FECG is easily interfered by noise, which makes the signal quality decline, leading to the fetal heart rate (FHR) monitoring becoming a challenging task. In this work, an algorithm for dynamic evaluation of signal quality is proposed to improve the multi-channel FHR monitoring. The innovation of the method is to assess the signal quality in the process of multi-channel fetal QRS (FQRS) complexes detection. Specifically, the detected FQRS is used as quality unit. Each quality unit can be a true R peak (TR) or a false R peak (FR). It is the basic quality information in this work. The signal quality of each channel is estimated by estimating the correctness of the detection results. Further, the TRs of all channels can be fused to obtain more reliable fetal heart rate monitoring. Analysis results demonstrate that the proposed algorithm is capable of selecting the good quality signal for FQRS detection achieving 97.40% PPV, 98.33% SE and 97.86% F1. This work sheds light on the quality assessment of fetal monitoring signal.

Parents' preferences for respite care of children with medical complexity

AbstractBackgroundThe number of children with medical complexity (CMC) is increasing worldwide. For these children and their families, various forms of support are legislated; among them, short‐stay respite care has a great unmet need. We examined such children's parents' preferences for respite care and their willingness to pay.MethodsWe used discrete choice experiments (DCEs) to estimate the parents' preferences and willingness to pay. Parents whose children used overnight short‐stay respite services answered a questionnaire to compare two hypothetical facilities of respite care having seven attributes and three levels. The DCE data was analyzed using the conditional logit model. The willingness to pay was calculated based on DCE estimates.ResultsA total of 70 parents participated in this study and mean age of their children was 7.8 years (standard deviation [SD] 4.3). Among those children, 67 (96%) had the severest certification of disability, and 27 (38%) used a ventilator at home. We found that the parents' highest preferences was the best level of medical care level that can manage ventilators (coefficient 1.61, 95% confidence interval [CI]: 1.32–1.90). The better and best level of medical care, daily care, education/nursing, and emergency care were preferred over basic quality services. Willingness to pay for the best level of medical care was approximately 75,367 JPY per night.ConclusionThis study shows a need for respite care that can deliver high‐level medical care, especially for the management of ventilators, to CMC. This finding can serve as a basis for promoting respite care services.

An Integrated Approach of Hypobaric Pressures and Potassium Permanganate to Maintain Quality and Biochemical Changes in Tomato Fruits

Limited postharvest life of tomato fruit is due to its highly perishable nature. Hypobaric pressure is a new emerging hurdle technology usually used up to a pressure of 100 kPa for the preservation of fruits and vegetables. In this study, an integrated approach of hypobaric pressures (40 kPa and 50 kPa) and sponge-dipping of potassium permanganate (KMnO4) was designed for the postharvest life extension of tomato fruits. Fruits were treated with either 400 ppm of KMnO4, or 40 or 50 kPa hypobaric pressures, or their combination. Fruits without any treatment was considered as a control treatment. All groups were packaged in polypropylene trays as ready to retail and stored at room temperature at 25 ± 1 °C for 21 days. Basic quality parameters such as pH, total soluble solid, percent weight loss, percent spoilage, firmness, ethylene production rate, and color were evaluated at 3-day intervals. Results showed the application of hypobaric pressures and KMnO4, either alone or in combination, provided a synergistic effect in maintaining the quality compared to the control treatment during the 21 days of storage. The highest decay was found in the control compared to the combined treatments of KMnO4 + 40 kPa and KMnO4 + 50 kPa. Similarly, a decrease in firmness and color values was highest in the control treatment followed by the KMnO4 and 50 kPa hypobaric pressure compared to the combined treatment of KMnO4 + 50 kPa. In the same way, a high ethylene production rate was observed in the control, while the lowest ethylene production rate was found in KMnO4 + 50 kpa. Sensory evaluation indicated a highest score of 9 on the 9-point hedonic scale of tomato fruits. Among all groups, the combined application of 50 kPa hypobaric pressure + 400 ppm KMnO4 retained the best overall quality attributes compared to all other treatments throughout the experiment; therefore, this treatment could be applied at a commercial level for tomato fruits.

Key factors for the success of smart ports during the post-pandemic era

In view of the complexity of maritime transport and the lack of a unified indicator system to evaluate smart ports, this study analyzed the basic characteristics and service quality of smart ports in the post-pandemic era using the SERVQUAL service quality scale. This study further developed an expert questionnaire based on 25 evaluation indicators and evaluated the key indicators of smart port service quality and their causal relationships using the analytic hierarchy process (AHP) and decision making and trial evaluation laboratory (DEMATEL). The results of this study showed that the key smart port success factors are: (1) accurate and secure delivery of cargo; (2) accurate electronic document transfer; (3) rapid provision of port berths to shorten the turnover time of ships; (4) convenient and comprehensive logistics and customs procedures; (5) transparent information integration on a single platform; and (6) use of big data to arrange container transport. Causal relationships were found among the indicators, including the fact that "convenient and comprehensive logistics and customs procedures" was influenced by “accurate electronic document transfer," "transparent information integration on a single platform," and "use of big data to arrange container transport." The results of this study can help port operators and government agencies identify key success factors for smart ports. This will enable participants in the supply chain to take early measures to respond to the impact of emergencies in the post-pandemic era, thus improving port operations and customer satisfaction. This research provides a standard model of smart port service quality that can serve as a reference for building a competitive advantage and making sustainable management decisions.

Evaluation of the ef fect of native arbuscular mycorrhizal fungi an vermicompost leachate on the yield and quality of f ield-grown peanuts

The improvement of the symbiosis generated by arbuscular mycorrhizal fungi (AMF) against pathogenic microorganisms has been described, however, the ef fect of AMF in peanut crops is of interest due to the value of the productive chain that has not been fully attended. Therefore, this research work evaluated six treatments: (T1) Control plants without AMF, (T2) Plants with vermicompost leachate, (T3) Plants inoculated with commercial mycorrhizae, (T4) Plants inoculated with native mycorrhizae, (T5) Plants inoculated with commercial mycorrhizae + leachate and (T6) Plants inoculated with commercial mycorrhizae + native mycorrhizae; in this sense, mycorrhizal fungi were isolated, identifying Rhizoglomus clarum, Acaulospora alpina and Acaulospora af f. bireticulata, and inoculated in peanut plants in an area of 144 m2 in the open, so that, to corroborate the incidence of the treatments evaluated, agronomic variables such as height, width of biomass, foliar damage by Cercospora personata, number of f lowers, were evaluated during the pre-harvest every 15 days and the post-harvest variables were; leaf area index, root length, fruit and lipid yield, as well as the prof ile of fatty acids present in the fruit. Finally, peanut quality was evaluated according to CODEX STAN 200-1995, showing that the best treatment was leaching + commercial mycorrhizae, reporting yields of 65.05% of fruits and 58% of total lipids, mostly monounsaturated fatty acids (52 % oleic acid) followed by polyunsaturated (21% linoleic acid), f inally according to CODEX STAN 200-199 the peanuts obtained correspond to the basic quality with dimensions of 4 to 4.5 cm wide and long respectively, these peanuts cannot be exported but they can be marketed in the country for agro-industrial transformation, allowing improved agricultural practices by reducing the use of agrochemicals.

Risk-Based Inspection and Rehabilitation Planning of Service Connections in Intermittent Water Supply Systems for Leakage Management in Arid Regions

Most of the leakage in water distribution systems operating with plastic pipes occurs at service connections (SCs), while the existing tools plan rehabilitation of pipes. With limited water resources, intermittent supplies in arid regions further enhance the failure vulnerability of metal fittings on water mains due to scale formation and large pressure transients. The present research developed a risk-based methodology for the proactive maintenance of SCs in intermittent water supply systems. A five-generation bottom-up hierarchical approach aggregated the basic hydraulic, physical, and water quality factors to determine the vulnerability of structural failures of SCs. Hydraulic parameters (pressure and velocity) were estimated by simulating a distribution network of 366 water mains of diameters ranging from 110 mm to 225 mm serving 371 SCs in a residential neighborhood located in the Qassim region of Saudi Arabia. Age, depth, and length of SCs’ estimated the condition index, while soil corrosivity and condition of the water mains were also counted when assessing the structural failure index for each SC. Water quality parameters, e.g., pH, turbidity, and iron, that can contribute to the vulnerability of an SC’s failure were also included. Fuzzy-based methods first assessed the relative importance weights of the basic input parameters at the bottom of the hierarchy and the risk factors in the middle of the hierarchy. Subsequently, the performance and condition scores were aggregated to develop respective indices. As the consequence of structural failure is high for the SCs serving households with a large number of residents, the final risk index aggregates the vulnerability and consequence at the hierarchy’s top. The developed model was effectively validated by comparing the SCs of high priority with the leaking and repaired SCs in the past. The method will be a useful tool for planning proactive inspection and rehabilitation of SCs of intermittent supply systems to minimize water losses (less than 8% of the national benchmark) in Saudi Arabia and elsewhere.

Basic Psychological Needs, Leisure, and Quality of Life for Wheelchair Users

Basic Psychological Needs, Leisure, and Quality of Life for Wheelchair Users

Improvement Productivity and Quality by Using Lean Six Sigma: A Case Study in Mechanical Manufacturing

Intelligent integrated production systems are always of interest to production planners. However, in order to deploy and improve from a mere processing fac- tory to a processing factory with an integrated intelligent production system, it requires a team of employees, engineers, and managers to always have a spirit of innovation, continuously improving existing semi-automatic equipment into automatic ones, aiming to move towards a smart factory. The result of this research is to reduce waste in the process of assembling mechanical products by applying the DMAIC process (Define, Measure, Analysis, Improve, Con- trol), lean six sigma tools, the test of variance, hypothesis testing and exper- imental design, IBM SPSS 2020, Matlab2019a and Minitab 18 software are used for data analysis and Solid work software is used to design and simulate mechanical parts. This study shows a systematic approach to analysis to find the root cause of defects in the product assembly process, a method of diag- nosing defective products as well as the application of charts to the analysis of waste products, and improving quality by applying basic quality manage- ment tools such as Pareto charts, fishbone diagrams, value stream mapping, man-machine chart, and failure tree analysis (FTA). Clearly identify the types of waste such as components sliding on top of each other without rust, and sur- face roughness of metal products that do not meet the standards. Experimental design models and statistical models, and statistical tests are applied to Lean six sigma’s DMAIC model in the process of analyzing the machining process. The results of analysis and process improvement have improved in a reduc- tion of scrap in the assembly line of mechanical products by 59.66% per year, an increase in assembly-line productivity by 7.8% per year, and a decrease in waste costs incurred by 59.66% per year. The application of the DMAIC cycle to improve the quality of the assembly line of mechanical products, in addition to reducing waste, also reduces the quality cost of the assembly line.

ESG approach in the valorization of cocoa (Theobroma cacao) by-products by subcritical water: Application in the cosmetic industry

In this research valorization potentials of cocoa hull extracts in cosmetic industry, following Environmental, Social, and Governance (ESG) criteria, have been investigated and reported, presenting increased value of this biowaste. The extracts of cocoa hull obtained by subcritical water were characterized in respect to chemical composition and certain bioactive properties, and were used to develop functional cosmetic formulation. In this work cocoa hull of cocoa beans originating from different geographical locations (Ivory Coast, Ghana, Togo, Grenada) were extracted by subcritical water to obtain functional extracts rich in valuable compounds. The extracts were characterized in respect to their total proteins (10–27%), total phenols (37–45 mg GAE/g) and total flavonoids (14–21 mg RE/g) contents. In addition, the minerals K (41–60 mg/100 g), Na (0.78–1.17 mg/100 g), and Ca (2.47–5.94 mg/100 g) were also quantified. Antiradical activity against DPPH (IC50 ∼ 11–13 μg/ml) and ABTS (IC50 ∼ 7–9 μg/ml) radicals, as well as total antioxidant activity (∼14–20 mg EAK/100 g DE), were determined and compared for all extracts. The extract with the highest antioxidant and antiradical activity was used for the formulation of a functional cosmetic product – a day cream with sun protective properties and added qualities. The prepared facial cream was analysed in respect to basic quality parameters for cosmetic products, proving the safety of the newly developed product based on subcritical water extracts of cocoa hull. The application of subcritical water extraction, as a green technology, can significantly enhance the ESG development in the cosmetic industry.

Numerical modeling and rational methods of water supply network operations in environmental engineering systems

This research paper uses a numerical modeling process to recreate the actual operating conditions of the water distribution system in the town of Kleosin, located on the border with Bialystok. The performed calculations allowed for the creation of a model for the functioning of the water supply network and for taking rational and optimal decisions affecting the effective operation of the entire system. The numerical modeling process is presented as a common tool to rationally and optimally manage the water distribution system. At the same time, numerous possibilities of computationally modeling and processing accurate real data were presented. The scope of the study included the network model analyzed in terms of the basic quality parameters that the network should meet, such as flow velocity, pressure, unit losses, water age, and operating conditions during simulated events, such as expansion or system failure, broken down into assumed time variants. As part of the paper, a situational variant was presented, which concerned the planned modernization in order to improve the functioning of the system by extending water distribution with new sections. The Epanet computer program distributed by US EPA was used in the research.

Wheat Bread Supplemented with Agaricus bisporus Powder: Effect on Bioactive Substances Content and Technological Quality

Supplementation of food products with mushroom powder increases their health-promoting value, but at the same time affects technological quality, which often play a key role for consumers. The aim of the research was to determine the effect of adding freeze-dried white and brown button mushrooms (2.5% and 5%) to wheat bread on its health-promoting properties such as antioxidant activity (DPPH, FRAP), total polyphenols and vitamin D2 content and as well as the technological quality as colour and texture. The breads were supplemented with mushroom lyophilisates, which were exposed to UVB radiation in order to increase their vitamin D2 content. The content of total polyphenols and antioxidant properties were determined spectrophotometrically, and the content of vitamin D2 by ultra-high performance liquid chromatography coupled to triple quadrupole spectrometer (UHPLC/MS/MS analysis). Colour parameters were determined in the CIE-Lab system and texture profile analysis (TPA) and sensory evaluation of the baked products were performed. The addition of dried mushrooms significantly increased the content of bioactive compounds (total polyphenols, vitamin D2) and the antioxidant properties of bread. A small addition of mushrooms caused a significant change in the basic technological quality of breads (colour parameters, specific volume, hardness, cohesiveness, springiness). At the same time, supplementation with mushroom lyophilisates has a positive effect on most analysed attributes in the nine-point hedonic scale. Based on the conducted research, it can be concluded that mushroom lyophilisates can be a valuable raw material for the fortification of bread, which is a good matrix and carrier of substances with documented biological activities.

A probability prediction method for the classification of surrounding rock quality of tunnels with incomplete data using Bayesian networks

The classification of surrounding rock quality is critical for the dynamic construction and design of tunnels. However, obtaining complete parameters for predicting the surrounding rock grades is always challenging in complex tunnel geological environment. In this study, a new method based on Bayesian networks is proposed to predict the probability for the classification of surrounding rock quality of tunnel with incomplete data. A database is collected with 286 cases in 10 tunnels, involving nine parameters: rock hardness, weathering degree, rock mass integrity, rock mass structure, structural plane integrity, in-situ stress, groundwater, rock basic quality, and surrounding rock level. Moreover, the Bayesian network structure is built using the collected database and quantitatively verified by strength analysis. Then, the accuracy, precision, recall, F-measure and receiver operating characteristic (ROC) curves are utilized for model evaluation. The average values of accuracy, precision, recall, F-measure, and area under the curve (AUC) are approximately 89.2%, 91%, 92%, 91%, and 0.98, respectively. These results indicate that the established classification model has high accuracy, even with small sample size and imbalanced samples. Ten additional sets of tunnel cases (incomplete data) are also used for verification. The results reveal that compared with the traditional Q-system (Q) and rock mass rating (RMR) classification methods, the proposed classification model has the lowest error rate and is capable of using incomplete data to predict sample results. Finally, sensitivity analysis suggests that the rock hardness and rock mass integrity have the strongest impact on the quality of tunnel surrounding rock. Overall, the findings of this study can serve as a useful reference for future rock mass quality evaluation in tunnels, underground powerhouses, slopes, etc.

Health disparities in regional anesthesia and analgesia for the management of acute pain in trauma patients.

Health disparities in regional anesthesia and analgesia for the management of acute pain in trauma patients.

Summer Buffalo Milk Produced in China: A Desirable Diet Enriched in Polyunsaturated Fatty Acids and Amino Acids.

The objective of the study was to compare and reveal differences in basic chemical parameters, fatty acids, amino acids, and lipid quality indices of crossbred buffalo (swamp x river type) milk produced in summer and winter. The buffalo milk samples were collected in summer (Jul-Aug) and winter (Dec-Jan) from Hubei province, China. The samples were detected by using CombiFoss apparatus, gas chromatography, and an automated specialized amino acid analyzer. The results showed that the basic chemical parameters, fatty acid profiles, lipid quality indices, and amino acid profiles of crossbred buffalo milk differed between summer and winter. Specifically, summer buffalo milk exhibited a higher content of MUFA (monounsaturated fatty acids) and PUFA (polyunsaturated fatty acids) than winter buffalo milk. Summer buffalo milk had a lower content of major SFA (saturated fatty acids), a higher content of ω-3 and DFA (hypocholesterolemic fatty acids), a lower ω-6/ω-3 ratio, a higher value of 3 unsaturated fatty acid indices (C14, C16, C18), and a lower value of IA (index of atherogenicity) and IT (index of thrombogenicity) than winter buffalo milk. Additionally, 17 amino acids, including 8 EAA (essential amino acids) and 9 NEAA (non-essential amino acids) were higher in summer buffalo milk. These results indicated that summer buffalo milk was more health-beneficial than winter buffalo milk. Therefore, summer buffalo milk might be a desirable diet option for human nutrition and health. Our findings provide valuable information for the research and development of buffalo dairy products in China or other Asian countries.

A Study on Water-based Paints Applied for Art Makeup

In creating works of ‘Art Makeup’ called ‘the pinnacle of makeup’ specific and systemic learning is required for inexperienced beginners or students to acquire basic knowledge or quality of art makeup. For this reason, we analyzed characteristics of water-based paints in order to examine what changes in colors there were when these paints mixed with water were applied to the skin and became completely dry in a certain time. We also looked into their consistency-how long they lasted against drying speed, stimulation or contact. The findings are as follows. First, in the water-based paints we analyzed, we saw color fading with change in color purity and decreased saturation compared to original products when they were completely dry. Especially, in the case of achromatic color, white, completely dry, decreased in lightness, resulting in very low whiteness compared to the original product, whereas black, completely dry, increased in lightness, resulting in low blackness compared to the original product. Therefore, in expressing works with black and white in high lightness, it would be better if achromatic color is used for the sake of painting over or applying a little achromatic color on a small part of the skin for highlight effect. Second, water-based paints which are applied to the works undergo a drying process to preserve the works. In the drying process, we found a very large deviation in time depending upon color. Hence, in creating art makeup works, arranging sequence of colouring needs to take into account the drying speed which varies depending upon color. Finally, water-based paints had consistency against stimuli such as a little bit movement unless there were direct stimuli to them after they were applied to the skin and became completely dry. But they turned out to be vulnerable to watery stimuli such as sweat. Therefore, location, lighting, and temperature should be taken into consideration in creating works. Especially, in a sweating-triggered environment, a lot of attention should be paid to keep the works intact. If necessary, water resistant products may be a good choice.

Research on Regional Basic Education Quality Assessment Based on Deep Convolutional Neural Network

At present, the informatization of basic education quality assessment has become a hot topic in the field of education and is playing an increasingly important role. Based on the theory of deep convolutional neural network, this paper adopts the methods of mathematical analysis and experimental research to construct a regional basic education quality assessment model. The model solves the data informatization problem of education quality assessment. In the simulation process, two key modules of data self-assessment and expert assessment of the deep convolutional neural network are realized by ASENET+SQL SERVER, and the assessment results are integrated by using the weighted average method and the fuzzy comprehensive assessment method. The experimental results show that the quantitative analysis of the quality assessment is carried out by using the logic and support relationship, and the results of comprehensive qualitative analysis and quantitative analysis are realized and segmented when the threshold level is 9, the MIOU obtains the highest value of 0.7501, and the MIOU of the multi-stage method of the quality evaluation model proposed in this paper is 0.8116, which is 6.15% points higher than the traditional multi-stage algorithm, which effectively improves the current stage area quality of basic education.

Excessive sulfur oxidation in endoplasmic reticulum drives an inflammatory reaction of chondrocytes in aging mice.

Osteoarthritis, as a common joint disease among middle-aged and elderly people, has many problems, such as diverse pathogenesis, poor prognosis and high recurrence rate, which seriously affects patients' physical and mental health and reduces their quality of life. At present, the pathogenesis of osteoarthritis is not completely clear, and the treatment plan is mainly to relieve symptoms and ensure basic quality of life. Therefore, it is particularly urgent to explore the pathogenesis of osteoarthritis. Protein, as organic macromolecule which plays a major role in life activities, plays an important role in the development of disease. Through protein omics, this study found that with the increase of age, excessive sulfur oxidation occurred in endoplasmic reticulum of chondrocytes, which then drove the occurrence of inflammatory reaction, and provided a direction for the follow-up molecular targeted.