Attractive Sites Research Articles

Assessing wastewater pollution from outdoor night markets and its impacts on river quality.

Night markets are attractive tourist sites in Asian cities. However, the outdoor activities produce different types of pollutants. Air pollution and solid waste in night markets have received much attention, but wastewater pollution from night markets has rarely been examined. The untreated wastewater are discharged into roadside gutters and might contaminate receiving waterbodies. In this study, night markets in Taipei city, Taiwan, were surveyed to clarify the characteristics of wastewater. The sampled wastewater showed high levels of organic substances, oil and grease, and phosphorous but low levels of nitrogen compounds. In addition, the unit pollution loads in night market stalls were obtained. The BOD load of each stall in the night markets was 2,509 g/day, which is higher than the sewage emissions of 50 people. In order to know the impacts of night market wastewater on the receiving waterbody, a water quality model, the Water Quality Analysis Simulation Program (WASP), was used in the studied river, Keelung River. If night market wastewater could be collected (not discharged), the BOD concentration could be reduced by 9.8%, but the NH3-N and DO concentration could be reduced by less than 1%.

Solid-liquid interface adsorption of antibiotic resistance plasmids induced by nanoplastics aggravates gene pollution in aquatic ecosystems

Antibiotic resistance genes (ARGs) and nanoplastics (NPs) have been identified as emerging pollutants in water environment; the interactions between antibiotic resistance plasmids (ARPs) and NPs will influence ARG transport in sediments. Herein, the adsorption experiments of a typical ARP onto polystyrene nanoplastics (PS-NPs) in river and lake sediments were conducted to elucidate the adsorption mechanisms and the effects of environmental factors. Results indicated that the adsorption amounts of PS-NPs increased with the dosages while decreased with the particle size of sediments. Multi-layer adsorption of PS-NPs was found to exist mainly in sand and silt sediments, whereas the filling adsorption dominated in the clay. Moreover, the adsorbed PS-NPs enhanced the physisorption of ARPs in sediments through stimulating the intraparticle diffusion of ARPs induced by electrostatic force. Besides, the adsorption amounts of ARPs onto the PS-NPs decreased with the increasing pH and dissolve organic matter due to the enhanced electrostatic repulsion and competitive adsorption. The ion strength played catalytic roles by increasing the electrostatic attraction and adsorption sites of ARPs on PS-NPs. The adsorbed ARPs in sediments were closely related with the ARGs in extra/intracellular DNA of biofilms, influencing the distribution and proliferation of ARGs largely. The findings indicate that ARG-associated pollution might be enhanced by the solid-liquid interface adsorption induced by NPs, which was controlled by pH, ion strength and dissolve organic matter. This study provides supplementary insights into the roles of NPs as carriers of ARP in sediments, and advances our understanding on the risks of NP-ARG co-occurring contamination in aquatic ecosystems.

Anomalous phase behavior of quasi-one-dimensional attractive hard rods.

We study a two-state model of attractive hard rods using the transfer matrix method, where the centers of the particles are confined to a straight line, but the orientations of the rods can be parallel or perpendicular to the confining line. The rods are modeled as hard rectangles with length L and width D and decorated with attractive sites at both ends of the rectangles. We find that the particles align parallel to the line and form long chains at low densities, while they turn out of the line and form a Tonks gas at high densities. With increasing the stickiness between the rods, the structural change between parallel and perpendicular states becomes stronger and the pressure vs density curve becomes almost a horizontal line at the transition pressure. We show that such a behavior is reminiscent of the first-order phase transition. This manifests in the validity of the lever rule of the phase transitions for very sticky cases.

Alternating one-phase and two-phase crystallization mechanisms in octahedral patchy colloids.

Colloidal systems possess unique features to investigate the governing principles behind liquid-to-solid transitions. The phase diagram and crystallization landscape of colloidal particles can be finely tuned by the range, number, and angular distribution of attractive interactions between the constituent particles. In this work, we present a computational study of colloidal patchy particles with high-symmetry bonding-six patches displaying octahedral symmetry-that can crystallize into distinct competing ordered phases: a cubic simple (CS) lattice, a body-centered cubic phase, and two face-centered cubic solids (orientationally ordered and disordered). We investigate the underlying mechanisms by which these competing crystals emerge from a disordered fluid at different pressures. Strikingly, we identify instances where the structure of the crystalline embryo corresponds to the stable solid, while in others, it corresponds to a metastable crystal whose nucleation is enabled by its lower interfacial free energy with the liquid. Moreover, we find the exceptional phenomenon that, due to a subtle balance between volumetric enthalpy and interfacial free energy, the CS phase nucleates via crystalline cubic nuclei rather than through spherical clusters, as the majority of crystal solids in nature. Finally, by examining growth beyond the nucleation stage, we uncover a series of alternating one-phase and two-phase crystallization mechanisms depending on whether or not the same phase that nucleates keeps growing. Taken together, we show that an octahedral distribution of attractive sites in colloidal particles results in an extremely rich crystallization landscape where subtle differences in pressure crucially determine the crystallizing polymorph.

Tourism Products and Tourist Satisfaction in Nech Sar National Park, Ethiopia

Nech Sar National Park is one of the potential sites for tourism & conservation of wildlife including the endemic and flagship specie. The objective of the study was to investigate the tourism products and tourist satisfaction in the Park. For the better success of the study design that integrates both quantitative and qualitative research methods. Primary & secondary information sources have also been used; the primarily data collection was made using direct observation. Potential tourist attraction site was recorded with Canon digital camera & Garmin 64 GPS based field observations were used. Questionnaires were used to investigate tourist satisfaction in the park. Secondary data were collected from review of relevant different related publications and document reviews. Data were analyzed using descriptive statistics, MSEXCL programs, QGIS software. According to the finding of the study, majority of tourism products of the park are: Forty springs, God’s bridge, Degabule viewpoint, Chamo view point, Nech Sar Plains, Sermaly River valley, Mountains chains, Ayemero Selassie Cave, Emporer Haile Selassie, Colonial Mengistu Hailemariam, Hot spring & tourism wild animals. Overall tourist satisfaction indicated, majority 84.5 % & 15.5 % visitors were satisfied & highly satisfied, respectively. Visitors source of information were 34.5%, 23.5%, 15%, 14%, 8% & 4.5% from friend, Internet, Tour Operators (Travel agents), written books, Ethiopian airlines & catalogs, respectively. Tourists Tourism product preference 33% Forest admirers, 19% wild animals18.5% Land scenery, 11.5% Trekkers, 10.5% Boat recreations & 7.5% Bird watchers. Infrastructures problems for visitors from 44.3% faced road problems, 21% waste disposal, 10.7% security, 9% Boat trip, & 9% professional local guides. Tourist Flow and income generated status in National Park increasing before the outbreak of covid-19 pandemic virus from 1987-2011 E.C. May - August, 2012 E.C tourist flow and revenue collection was zero, due to the occurrence of the pandemic covid-19 virus. 2014 E.C 800,000 ETB has been collected from National Park visitors that were collected from the entrance fee. Major tourism products problems in the park include grazing plain; illegal fishing two lakes, settlement and illegal farming, natural resource extraction, & Invasive and encroaching Plant Species. The government should promote the National Park & provide appropriate support for its conservation. Keywords: Tourism products, Tourist satisfaction, Tourism animals DOI: 10.7176/JTHS/33-02 Publication date: October 31 st 2022

IDENTIFYING TRAVEL MOTIVATIONS OF SAUDI DOMESTIC TOURISTS: CASE OF HAIL PROVINCE IN SAUDI ARABIA

This study focuses on Saudi domestic tourists visiting Hail province. The objectives of this study are to explore the perception of tourists regarding Hail province and to identify the main motivational factors that attracts them to travel to Hail. This study was conducted in Hail region located in north of Kingdom of Saudi Arabia. Visitors over 18 years of age in attraction sites in the destination were potential respondents for the present study. Convenient sampling technique was applied to gather data from respondents. Over 650 questionnaires were distributed among visitors in Hail region, out of which 380 were used for analysis as the remaining questionnaires were not fit for use due to their incomplete responses. Factor analysis and cluster analysis were undertaken to identify travel motives or intentions of tourists. The identified motivational factors illustrated that “taking part in new adventures”, “relaxation”, “increasing tourism knowledge”, and “escaping routine” were the most important reasons of Saudi tourist to visit Hail region. The cluster analysis result shows that “relaxation” is the top motivational factor for tourists who visit Hail followed by “increasing tourism knowledge”. This study gives important recommendations for planners in the Saudi Tourism Commission and National Heritage and Entertainment Authority to take development of Hail destination as priority for domestic and international tourism travelers. The decision and policy makers should create tourism packages, products and programs based on push and pull factors which impact the motivation factors of the travelers to make Hail as the major tourist destination.

Jordan Space Research Initiative: Societal Benefits of Lunar Exploration and Analog Research

Jordan's political stability has aided in the country's notable rapid growth these past few years, despite its limited natural and financial resources. Jordan is currently taking the lead in multiple sectors in the region, such as Education, Medicine, Information and Communications Technology, and more. The advancement of these industries has encouraged the progress and development of the Jordanian community as well. Similarly, space can contribute societal benefits in an emerging space country like Jordan. Under the Moon Village – Participation of Emerging Space Countries (MV-PESC) program, a roadmap for Jordan's contribution to lunar exploration and the Jordan Space Research Initiative (JSRI) were created. This 20-year roadmap focuses on establishing an analog R&D facility for Moon and Mars in the Jordanian desert of Wadi Rum, locally known as the Valley of the Moon. This roadmap aims to support the following building blocks: Water Resource Management, Renewable Energy, In-situ Resource Utilization (ISRU) and Robotics, Dust Mitigation, Agriculture, Smart City Infrastructure, and Women's Health. These building blocks will advance research required for the Moon Village, while simultaneously contributing to sustainable development in Jordan. Due to the national importance which Wadi Rum holds, for being a tourist attraction site, a naturally protected area, and a homeland for the local nomadic tribes (The Bedouins), community engagement is a crucial aspect of this roadmap. Finding an appropriate way of approaching the local community in Wadi Rum, the general public in Jordan, local authorities and the government, as well as fostering international cooperation in the space community, is crucial to its success. This paper investigates how the implementation of the Moon Village PESC project in Jordan, as embodied by JSRI, will contribute to solving some of its most pressing societal and economic issues, such as water scarcity, while highlighting how the incorporation of space technology and research will play a major role in advancing Jordan's existing research goals and initiatives. By linking the roadmap developed by JSRI to the preliminary Roadmap for Space and Sustainable Development (RSSD), which was introduced in a previous IAC paper titled “Jordan and the United Nations Space2030 Agenda: A Roadmap for Space and Sustainable Development” (2020), this paper also identifies ways in which the implementation of the Moon Village in Jordan will contribute to the achievement of the objectives of the UN Space2030 Agenda and the Sustainable Development Goals.

Use of Subsurface Geology in Assessing the Optimal Co-Location of CO2 Storage and Wind Energy Sites

Opportunities exist to re-purpose depleted gas fields in the Southern North Sea as CO2 storage sites if, where and when they meet the right set of geological, engineering, and non-technical criteria. Fields positioned on the western edge of the basin are attractive as they lie close to the major industrial emitters of East England which need to decarbonise if the UK’s Net Zero targets are to be met. Having stopped production in 2018, Pickerill has CO2 storage potential as it is a proven trap from which around 440 Bcf of gas has been produced and it is located near the coastline. We use a public-domain 3D seismic dataset, wireline logs, core reports and production data to assess its CO2 storage potential. The Rotliegend Group reservoir (Leman Sandstone Formation) is a mixed aeolian/fluvial succession with variable thickness (25 m–80 m), high net-to-gross (0.9–1.0), moderate average porosity (9%–17%) and fair-average permeability (>1 mD). The seal is Zechstein Group evaporites and carbonates which thin and swell in response to their post-depositional mobility (halokinesis), further affecting and deforming the overburden. The structure is defined to the south by a WNW-ESE-striking fault system, but the north of the field is characterised mostly by dip closure of the reservoir. NW-SE-striking faults transect the field and segment the structure into several compartments, three of which appear particularly good candidates for CO2 storage and have a combined CO2 storage capacity of 32 MtCO2. If combined with nearby satellite fields, there is potential for the development of a CO2 storage cluster capable of sequestering 60 MtCO2, however, this potential is challenged by the planned development of an offshore wind farm. Turbines fixed to the seabed over the field would restrict where new CO2 injection wells might be drilled and efforts to measure, monitor and verify the CO2 plume using conventional towed-streamer seismic. There is an urgent need to resolve the competition for offshore acreage to ensure that attractive CO2 storage sites like Pickerill are not disadvantaged but can play a full part in complementing alternative renewable energy sources within the energy transition.

Molecular Dynamic Simulation Reveals Structure Differences in APOL1 Variants and Implication in Pathogenesis of Chronic Kidney Disease.

Background: According to observational studies, two polymorphisms in the apolipoprotein L1 (APOL1) gene have been linked to an increased risk of chronic kidney disease (CKD) in Africans. One polymorphism involves the substitution of two amino-acid residues (S342G and I384M; known as G1), while the other involves the deletion of two amino-acid residues in a row (N388 and Y389; termed G2). Despite the strong link between APOL1 polymorphisms and kidney disease, the molecular mechanisms via which these APOL1 mutations influence the onset and progression of CKD remain unknown. Methods: To predict the active site and allosteric site on the APOL1 protein, we used the Computed Atlas of Surface Topography of Proteins (CASTp) and the Protein Allosteric Sites Server (PASSer). Using an extended molecular dynamics simulation, we investigated the characteristic structural perturbations in the 3D structures of APOL1 variants. Results: According to CASTp’s active site characterization, the topmost predicted site had a surface area of 964.892 Å2 and a pocket volume of 900.792 Å3. For the top three allosteric pockets, the allostery probability was 52.44%, 46.30%, and 38.50%, respectively. The systems reached equilibrium in about 125 ns. From 0–100 ns, there was also significant structural instability. When compared to G1 and G2, the wildtype protein (G0) had overall high stability throughout the simulation. The root-mean-square fluctuation (RMSF) of wildtype and variant protein backbone Cα fluctuations revealed that the Cα of the variants had a large structural fluctuation when compared to the wildtype. Conclusion: Using a combination of different computational techniques, we identified binding sites within the APOL1 protein that could be an attractive site for potential inhibitors of APOL1. Furthermore, the G1 and G2 mutations reduced the structural stability of APOL1.

Impact of Polydopamine Nanoparticle Surface Pattern and Roughness on Interactions with Poly(ethylene glycol) in Aqueous Solution: A Multiscale Modeling and Simulation Study.

A significant research effort in the past few years has been devoted to engineering synthetic mimics of naturally occurring eumelanin. One such effort has involved the assembly of oligomers of 5,6-dihydroxyindole (DHI), a synthetic precursor of polydopamine (PDA), into melanin-mimicking nanoparticles for use in a variety of applications with desired optical, photonic, thermal, and electrical properties. In many of these applications, the PDA nanoparticles are mixed with other polymers or oligomers, thus motivating this specific study to understand how the surface characteristics of the assembled PDA-nanoparticles affect their interaction with poly(ethylene glycol) (PEG) chains in aqueous solution. We use molecular dynamics (MD) simulations to study the interaction of linear 20-mer PEG chains with different PDA-nanoparticles assembled using four types of oligomers of 5,6-DHI: two isomers of 5,6-DHI 2-mers with the monomers bonding either at the 2-2' position (A-type isomer) or 7-7' position (B-type isomer), denoted as A:2-mer and B:2-mer, respectively, and a 4-mer and an 8-mer of B-type chemistry denoted as B:4-mer and B:8-mer, respectively. Using explicit-solvent atomistic MD simulations, we find that PDA-nanoparticle surfaces assembled from B:8-mer exhibit smaller density fluctuations of water molecules and, as a result, are relatively more hydrophilic than the PDA-nanoparticle surfaces assembled from A:2-mer, B:2-mer, and B:4-mer. The surface composition of PDA-nanoparticles assembled from A:2-mer contains relatively fewer hydroxyl (-OH) groups compared to PDA-nanoparticles assembled from a B:2-mer, B:4-mer, or B:8-mer, yet the sample of PEG chains show more collapsed and adsorbed conformations on A:2-mer nanoparticles' surface. To explain the atomistically observed behavior of PEG chains on the nanoparticles' surfaces, we use coarse-grained (CG) MD simulations and explain the roles of the pattern formed by the attractive sites (e.g.,-OH groups) exposed on the surface and the roughness of the surface on interactions with a genric PEG-like copolymer chain. By comparing atomistic and CG MD simulation results, we confirm that the -OH groups' pattern on the surface of the PDA-nanoparticle assembled from A:2-mer is patchier than the random or string-like patterns on the PDA-nanoparticle assembled from B:2-mer, B:4-mer, or B:8-mer, and it is this -OH groups' surface pattern that dictates the PEG chain conformations and adsorption on the PDA-nanoparticle surface. Overall, these results guide the design of chemically and physically heterogeneous nanoparticle surfaces for the desired polymer interaction and conformations.

Numerical analysis of the liquid-liquid phase separation in the antibody–human serum albumin mixtures in aqueous buffer solution

We present a theoretical study of colloidal stability of mixtures of immunoglobulin molecules and human serum albumin in aqueous buffer solution at physiological pH. The antibodies are pictured as an assembly of seven hard spheres assuming (on the average) the Y-like arrangement. Globular proteins are represented as hard spheres with attractive sites to bind immunoglobulin molecules. We use Wertheim’s thermodynamic perturbation theory to perform calculations of measurable properties. Parameters to describe the sizes of both species are taken from previous experimental studies. The immunoglobulin-human serum albumin interaction parameters were fitted on basis of the best agreement between theory and measurements, utilizing experimental data for the liquid–liquid phase separation. We calculated chemical potentials and the equation of state for the model mixture to determine the liquid–liquid part of the phase diagram. The agreement between our theoretical analysis and experimental data is in the range from qualitative to quantitative. The fitted immunoglobulin–human serum albumin attractive potential, leading the agreement with experimental data, appears to be of very short range.

Performance evaluation for demand responsive transport services: A two-stage bootstrap-DEA and ordinary least square approach

Demand responsive transport (DRT) services have often been introduced to provide flexible public transport services, especially for areas with dispersed demand. However, objectively evaluating the performance of DRT services is challenging. This study uses a two-stage bootstrapped DEA and Ordinary Least Square (OLS) approach to measure performance using the Taiwanese DRT services as the empirical setting. In the first stage, bias-corrected Data Envelopment Analysis (DEA) efficiency scores are calculated by employing the smoothed homogenous bootstrapped procedure (Simar & Wilson, 2000). In the second stage, a OLS regression model is used to explore the impact from external factors with bias-corrected DEA efficiency scores as the dependent variable. Model results confirm that more than half of DRT services have increasing return to scale. The model results also show heavy rail services bring significant negative impact to the DRT service performance. This finding implies the main users of DRT services are local residents with fewer intercity travellers who typically would use heavy rail for access. The model results can lead to an improvement strategy for DRT services, for example, having a strategy to attract tourists to use DRT services to access tourist attraction sites would be one way to increase demand which would have the added advantage of improving sustainability. This study evaluates how this might improve public transport network accessibility and concludes with recommendations of a way forward to provide more sustainable DRT services.

Geography of visitors to the historical and cultural heritage of the Carpathian region and prospects for the growth of tourist flows


 
 
 The purpose of this research is to assess the geography of visitors, problems and prospects for the growth of tourist flows of cultural and historical heritage on the example of Ivano-Frankivsk and Transcarpathian regions along the cross-border highway. The subject of the research is the analysis of the results of sociological research of historical and cultural heritage sites, assessment of the geography of visitors, problems and prospects for tourism flows, the state of use of cultural heritage sites in the studied region and their development as tourist attractions. The object of research is the system of tourist services provided by tourist sites of historical and cultural heritage, represented by historical and cultural reserves, museums, sacred buildings and other attractive cultural sites. The scientific novelty of the study is that development trends, problems, prospects for tourist flows in historical and cultural heritage of the Carpathian region of Ukraine were identified for the first time by analyzing the results of sociological research through a survey of a representative sample. Methodologically, according to the authors of the article, the study conducted with voluntary information from persons who work, manage or own a tourist facility is the most accurate, as it includes the expert assessment of persons who are permanently on the site. According to the results, the number of visits to most tourist sites does not exceed 5,000 people per year. The only facility that has received more than 100,000 visitors in the last two pandemic years is the attractive Hutsul Land in Bukovel. Geography of domestic tourists – the vast majority are tourists from Lviv, Ternopil, Ivano-Frankivsk, Kyiv region and the capital city (Kyiv). Geography of foreign visitors – the vast majority are tourists from Poland, Germany, USA, Hungary, Slovakia. More than half of the facilities in the survey are free for tourists, and the cost of a third of the facilities is not more than two dollars. The main problems for the growth of tourist flows are underdeveloped infrastructure as a significant barrier to the development of the tourist facility, insufficient finances for development; insufficient number of attractions within the facilities, insufficient number of cultural events held in tourist destinations. Insufficient advertising of a tourist sites closes the top five problems. Such data indicate the need to develop tourist facilities, provide management of institutions with more information about services and ways to increase the attractiveness of facilities and increase their monetization. The ways to solve the problems of the development of tourist facilities, according to their management, are the need for additional funding; solving problems with the infrastructure tourist destinations; the need to improve advertising; cooperation with tour operators, etc.
 
 

Sustainable ecotourism development and visitor satisfaction: the case of Bomfobiri Wildlife Sanctuary, Kumawu, Ghana

ABSTRACT The potential for sustainable ecotourism development in Bomfobiri Wildlife Sanctuary (BWS) addresses conservation needs, visitor satisfaction, and community benefits. The study assessed the tourist and exploitation values of the sanctuary using the Pralong model. The study purposively interviewed five key informants, and field studies were conducted to determine tourist and exploitation values of seven key attraction sites. Semi-structured questionnaires were administered to 215 respondents, selected from visitors who have completed guided tours in the sanctuary in a visitor satisfaction survey. The study revealed that most attraction sites are under-exploited, resulting in low economic gains. Pame hills and waterfalls are well exploited and ranked first in tourist and exploitation values. Seeing waterfalls was the top-ranked motivation for visiting the sanctuary and enhanced visitor satisfaction, followed by enjoying the views, learning about wildlife and nature, being close to nature, and having an adventure. However, care should be taken to avoid over-exploitation of the waterfalls area. Other attraction sites with great potential but under-utilised should be developed to boost their tourist value and minimise the impact of ecotourism on concentrating on a few sites. Tourists were generally happy with the attractions of the sanctuary and impressed with the friendliness of park staff and safety. Carefully planned and proper development of the sanctuary will ensure sustainability and continue delivering conservation goals, visitor satisfaction, and community benefits.

Women Participation in Tourism Entrepreneurial Opportunities in Minjingu Village, Manyara Region

Women's participation in the tourism industry contributes to the initiation of self-development projects. This study aimed at identifying tourism opportunities found in Minjingu Village by examining factors which affect women's participation in tourism business opportunities and strategise ways for improvement. To this effect, the study employed grounded theory, resource- based theory and financial capital theory were reviewed. Primary data was collected using questionnaires, interview, and observation. Secondary data was collected from various published studies like books and journals. The sample of 327 was picked for the study population of which 317 were women entrepreneurs and 10 were women leaders, village executive officer, hotel operators and tour operators. Data was analyzed using Statistical Packages for Social Sciences (SPSS version 16.0). The findings revealed that, the presence of tourism activities and services such as accommodation, game drive, cultural attraction sites; they provided various tourism entrepreneurial opportunities to women. They included selling items ranging from beads, woven baskets, curio and other cultural articles to tourists. Further, findings showed that, lack of financial capital and business skills, unstable market due to COVID-19 pandemic; and business competition significantly affected women participation in tourism business. The study concluded that women required to be empowered financially and in capacity building in various aspects to enable them to participate fully in tourism entrepreneurial activities for income generation. It recommended tourism stakeholders should establish centres for business skills training and provide financial support to improve women active participation in tourism business.

A Review on Orodispersible Tablet by Using Hibiscus rosa sinesis as Natural Superdisintegrant

Oral delivery is current standard in the pharmaceutical industry wherever it is regarded as the safest, most suitable and most economical method of drug delivery. The oral cavity is an attractive site for the administration of drugs because of ease of administration. Oro-dispersible drug delivery system are Novel Drug Delivery techniques that make the tablets disintegrate in the mouth without chewing and water, and immediate release and enhanced bioavailability, with better patient compliance. Orodispersible tablets (ODTs), also known as fast melt, quick melts, fast disintegrating have the unique property of disintegrating in the mouth in seconds without chewing and the need of water. Recently, the European Pharmacopeia adopted the term Orodispersible tablet for a tablet that disperses or disintegrates within a minute or second in the mouth before swallowing. Natural polymers remain attractive primarily because they are natural products of plants, readily available, inexpensive, and capable of multitude of chemical modification. Leaves of Hibiscus rosa sinensis Linn (Family: Malvaceae) contains high proportion of mucilage which can be used as additives in pharmaceutical formulations. The investigation of polysaccharides isolated from leaves of Hibiscus rosa sinensis Linn mucilage as a superdisintegrant in the formulation development of Orodispersible Tablets.

Optimization of Rural Smart Tourism Service Model with Internet of Things

Rural smart tourism is a new tourism form supported by information technology, especially the Internet of Things technology. Smart tourism not only makes it easier for tourists to get diverse tourism information, but it also helps attractive sites improve their service capabilities. The optimization of the rural smart tourist service model, which is explored in this work, includes personalized recommendations of scenic sites. The main research contents of the paper are as follows: (1) A new algorithm for recommending tourism destinations with domain adaptability has been suggested. In the field of personalized recommendation of tourist attractions, most of the target domain data are unlabeled, and the model cannot be trained. When it comes to training, however, there exist source domain data sets that are completely labeled and can be used as a supplement to the target domain training data sets. (2) A personalized recommendation algorithm for tourist attractions with deep migration has been studied. Owing to the distribution difference between target data and source data, an adaptive layer is added to the convolutional neural network. The domain loss is then minimized to achieve deep feature transfer, and the model can then be trained to find scenic areas of interest to the user. Finally, the recommendation for tourist destinations with deep migration is done by examining the relationship between the target user and other users.

Challenges for earthing system testing at fast-charging stations

The additional safety value regarding earthing system tests and measurements are often underrated or not properly considered during the planning phase of new construction projects or changes in electrical power systems, like fast-charging stations. The number of these charging stations is rapidly growing with the increasing popularity of e-mobility. Motorway service areas or restaurants are an attractive site for new fast-charging stations. A well designed and tested earthing system can assure personal and animal safety during phase-to-ground faults within the electrical network. To ensure that no hazardous touch-voltages appear at or in the surrounding areas of these stations, measurements according to standards like the EN 50522 [1] are performed. Within this paper we will outline the challenges of earthing system testing at such stations as well as provide you with information regarding the background of testing procedures, standards and theoretical and practical aspects.

Spectroscopic, Docking and MD Simulation Analysis of an Adamantane Derivative with Solvation Effects in Different Solvents

3-(Adamantan-1-yl)-4-(4-fluorophenyl)-1-{[4-(2-methyoxyphenyl)piprazin-1yl]-methyl}-4,5-dihydro-1H-1,2,4-triazole-5-thione (AFT) was synthesized and spectroscopic investigations have been made experimentally and theoretically. The electrostatic potential maps and frontier orbital visualizations were used to comment of molecular polarity and stability in AFT. In AFT, thione group, methoxyphenyl ring, and triazole are the strongest repulsion and attractive reactive sites. The chemical descriptors in different solvents and NLO properties are predicted. For different solvents and gas phase, UV-vis theoretical spectra are being used to assess the electronic transition. Solvation free energy in water (hydration free energy) indicates good solubility of AFT in an aqueous medium, factor that corroborates the biological activity, in as much as that bioorganic processes occur in aqueous medium. Solvation produces a lowering of absorption in the UV-vis region. After evaluating the drug likeness properties, the title compound was examined for its analgesic activity by means of molecular docking and MD simulations. The MD simulations and docking studies suggested inhibitory activity against analgesic protein glutamate receptor.

A Functional Organic Zinc-Chelate Formation with Nanoscaled Granular Structure Enabling Long-Term and Dendrite-Free Zn Anodes.

Aqueous Zn metal batteries suffer from rapid cycling deterioration due to the severe water corrosion and dendrite growth on Zn anodes. Herein, a highly antiwater Znx-diethylenetriaminepenta(methylene-phosphonic acid) interface layer with good zinc affinity and special nanoscaled 3D granular structure is designed on Zn metal to address these problems. Experimental results combined with theoretical analysis and COMSOL simulations reveal that the hydrophobic groups in such Zn-based organic complex are the decisive factor in preventing H2O from damaging Zn anode surface. The massive Zn2+ attractive sites formed by interaction of methylene-phosphonic acid groups and Zn cause ion channel for fast zinc-ion adsorption and migration. And the developed nano granular architecture on the surface induces redistributed Zn2+ ion flux to realize homogenization with smooth and compact surface deposition. Under the synergism, such modified anodes exhibit long cycling lifespan over 1300 h with a relatively low polarization voltage at 5 mA cm-2. Also, the assembled full cells (including Zn//V2O5 and Zn//MnO2 cell) based on this anode are also demonstrated. The work provides a simple, low cost, and efficient pathway by combining the two concepts of structural design and constructing protective layers on the surface to prepare high-performance Zn anodes toward prospering aqueous zinc-metal batteries.