Association Of Serum Lipid Profile Research Articles

Abstract C087: Association of serum lipid profile with prostate cancer risk and aggressiveness in Nigerian men

Abstract OBJECTIVE Though prostate cancer (PCa) is the most common cancer and cause of cancer death among Nigerian men, its relationship with serum lipid profiles, a biochemical measurement of dietary fat, has not been explored among Nigerian men. The study aimed to determine the association of serum lipid profile with prostate cancer risk and aggressiveness. METHODS The study was a case-control conducted at University College Hospital, Ibadan, Nigeria. The cases were newly diagnosed prostate cancer patients ages 50-75 years, while the controls were age-matched healthy men with confirmed normal PSA. Participants with uncontrolled comorbidities, poor performance status (ECOG ≥3), and weight loss in the past month were not eligible. The patient characteristics (age, marital status, employment status, highest level of education, high-fat diet, lack of exercise, tobacco smoking, alcohol intake, family history of prostate cancer, comorbidities, and tumor characteristics [PSA at presentation, histology, Gleason score, and stage at presentation] in the cases alone) were collected using an interviewer-administered questionnaire. A serum lipid profile test (including total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) was done in all participants. Analysis of the variables was on SPSS version 23.0, with a t-test to compare the serum lipid profile between the case and control groups, a chi-square to compare the sociodemographic and patient characteristics between both groups and an ANOVA test to determine the association between serum lipid profile and Gleason's score (disease grade) or stage of prostate cancer. RESULTS Enrolled in each group were seventy-four participants. The mean age ± standard deviation was 65.0 ± 5.9 years for cases and 63.0 ± 6.5 years for controls. Participants with a high-fat diet (p = 0.006), physical inactivity (p = 0.046), alcohol consumption (p = 0.005), and family history (p = 0.002) were significantly higher in the case group than the controls. A high proportion of the cases had high-grade disease (GS ≥ 8) [39.2%] and stage 4 disease (35.2%). The mean levels of TC (p<0.001) and HDL-C (p<0.001) were significantly higher in the cases. The mean TG increased while HDL-C decreased as the disease stage advanced but with no statistical significance. While the mean TC (p = 0.001) increased significantly with worsening prostate cancer grade, the mean HDL-C was highest in low-grade disease (p <0.001). CONCLUSION Elevated total cholesterol and high-density lipoprotein cholesterol were associated with increased prostate cancer risk. While elevated total cholesterol was associated with high-grade prostate cancer, a high level of high-density lipoprotein cholesterol was associated with the low-grade disease. Hence, regular serum lipid profile tests may be encouraged among Nigerian men for early detection and treatment of any cholesterol derangement to avoid its predisposition to prostate cancer. Citation Format: Kehinde Oluwatosin Adeyinka, Adeniyi Adenipekun, Atara Ntekim, Augustine Oghenewveyin Takure, Rotimi Solomon. Association of serum lipid profile with prostate cancer risk and aggressiveness in Nigerian men [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr C087.

Association of Serum Lipid Profile with Diabetic Retinopathy in a Tertiary Care Center in Tamilnadu, India

Background: Diabetes mellitus (DM) is considered to be a pandemic which impose a significant financial burden on developing nations in terms of resource management. As per the International Diabetes Federation 10th edition, the global prevalence in 2021 is 536.6 million, which is projected to increase to 783.2 million by 2045. The prevalence of Diabetic Retinopathy and its risk factors have generally received minimal attention, and eye screening compliance is often low. In order to further research and gain a better knowledge of the risk variables, this study is being done. Methods: The present study was cross sectional descriptive conducted in the Department of Ophthalmology, at a tertiary care centre in South India for 24 months. All patients who were diagnosed with Type 1 or Type 2 diabetes mellitus were included in the study while patients with cataract or retinopathy due to other pathologies were excluded. A recent lipid profile values of the participants were assessed. Their fundus was viewed and analyzed. Results: A total of 84 diabetic patients were included. Diabetic retinopathy, irrespective of the type, was found in 83 patients with a prevalence of 98.8%. Majority of the patients fell under the category moderate NPDR in our study. Among the lipid parameters, most of the cases have deranged triglyceride values of more than 150mg/dl. The association between the serum triglycerides and the severity of diabetic retinopathy as well as the association between the serum total cholesterol and the HbA1c was found statistically significant. Conclusion: The results of the current study clearly highlight the statistical association between the various lipid profile parameters and diabetic retinopathy. It enlightens the importance of proper lipid control in diabetic patients which in turn reduces the severity of diabetic retinopathy. Keywords: Type 2 diabetes mellitus, Diabetic retinopathy, Blindness, Lipid, Triglycerides

The association between serum lipid profile and the prostate cancer risk and aggressiveness.

This study aims to evaluate the association of serum lipid profile on prostate cancer (PC) risk and aggressiveness. Men who underwent prostate biopsy between January 2005 and December 2015 were retrospectively analyzed. The association between lipid profile and the risk, stage, and Gleason grade group (GG) of the PC were investigated. Sensitivity analysis was conducted using univariate and multivariate quantile analysis for lipide profile on the risk and stage of PC. Of the 1740 study populations, 720 men (41.4%) were diagnosed as PC. From multivariate logistic regression analysis, age, prostate specific antigen, triglyceride (odds ratio (OR):1.05, confidence interval (CI):1.03-1.07, p-value<0.001) significantly increased PC risk, while total cholesterol (OR:0.96, CI:0.92-0.99, p-value=0.011) significantly decreased the PC risk. The increase of serum triglyceride increased the risk of both of locally advanced (OR:1.03, CI:1.00-1.07, p-value=0.025) and metastatic PC (OR:1.14, CI:1.04-1.25, p-value=0.004). The increase of serum triglyceride increased the risk of GG2-3 (OR:1.03, CI:1.00-1.06, p-value=0.027) and GG4-5 (OR:1.04, CI:1.01-1.08, p-value=0.027). Univariate quartile analysis founded serum triglyceride increasing risk of locally advanced disease than organ confined disease. (OR: 1.00, 1.25, 2.04, 4.57 for 1st, 2nd, 3rd and 4th quartile, p-value<0.001). Adjusted multivariate quartile analysis confirmed statistically significant increasing PC risk of triglyceride (OR: 1.00, 1.25, 2.04, 4.57 for 1st, 2nd, 3rd and 4th quartile, p-value<0.001). This study findings suggested increased in triglyceride level increased the risk PC. Increased in triglyceride level also associated with aggressive presentation of PC, with higher stage and GG.

“Study of association of serum lipid profile, IL-6, &amp; ADMA levels with subclinical hypothyroidism”

Background &amp; Objectives: Subclinical hypothyroidism (SCH) represents the mildest form of thyroid hormone deficiency and may be associated with adverse consequences. SCH is defined as an elevated serum thyrotropin (often referred to as thyroid-stimulating hormone, or TSH) level with normal levels of free thyroxine (FT4) that affects up to 10% of the adult population. The identification of patients with subclinical hypothyroidism having an increased cardiovascular risk is of great importance in the present era. The aim of the study was to evaluate cardiovascular risk factors in patients with subclinical hypothyroidism.&#x0D; Methods: 120 patients with subclinical hypothyroidism and 120 age and gender matched healthy euthyroid controls in the age group of 18-70 years were included in the study. Body mass index (BMI), lipid profile, and levels of serum biomarkers were estimated in both the groups and further compared using student t-test. Lipid profile was also correlated with the serum ADMA &amp; IL-6 and the results were analyzed using Pearson’s correlation coefficient.&#x0D; Results: Patients with subclinical hypothyroidism had significantly higher levels of serum TSH, IL-6 and ADMA. Similarly, serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) were significantly increased and HDL-C was significantly decreased in SCH patients when compared to the same parameters of controls (p&lt;0.001). Significant positive correlations were found among lipid profile and serum IL-6 &amp; ADMA.&#x0D; Conclusions: The present study concluded that the SCH patients presented increased concentrations of cardiovascular disease (CVD) risk factors viz. IL-6, ADMA &amp; lipid profile. The potential benefits of diagnosis and treatment of subclinical hypothyroidism may have possible advantages firstly by preventing the progression to overt hypothyroidism and secondly decrease the risk of death from cardiovascular disease by starting appropriate therapy to improve lipid parameters.&#x0D;

“Study of association of serum lipid profile, IL-6, &amp; ADMA levels with subclinical hypothyroidism”

Background &amp; Objectives: Subclinical hypothyroidism (SCH) represents the mildest form of thyroid hormone deficiency and may be associated with adverse consequences. SCH is defined as an elevated serum thyrotropin (often referred to as thyroid-stimulating hormone, or TSH) level with normal levels of free thyroxine (FT4) that affects up to 10% of the adult population. The identification of patients with subclinical hypothyroidism having an increased cardiovascular risk is of great importance in the present era. The aim of the study was to evaluate cardiovascular risk factors in patients with subclinical hypothyroidism. Methods: 120 patients with subclinical hypothyroidism and 120 age and gender matched healthy euthyroid controls in the age group of 18-70 years were included in the study. Body mass index (BMI), lipid profile, and levels of serum biomarkers were estimated in both the groups and further compared using student t-test. Lipid profile was also correlated with the serum ADMA &amp; IL-6 and the results were analyzed using Pearson’s correlation coefficient. Results: Patients with subclinical hypothyroidism had significantly higher levels of serum TSH, IL-6 and ADMA. Similarly, serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) were significantly increased and HDL-C was significantly decreased in SCH patients when compared to the same parameters of controls (p&lt;0.001). Significant positive correlations were found among lipid profile and serum IL-6 &amp; ADMA. Conclusions: The present study concluded that the SCH patients presented increased concentrations of cardiovascular disease (CVD) risk factors viz. IL-6, ADMA &amp; lipid profile. The potential benefits of diagnosis and treatment of subclinical hypothyroidism may have possible advantages firstly by preventing the progression to overt hypothyroidism and secondly decrease the risk of death from cardiovascular disease by starting appropriate therapy to improve lipid parameters.

An Updated Systematic Review and Meta-Analysis on Association of Serum Lipid Profile With Risk of Breast Cancer Incidence.

This meta-analysis was performed to investigate the effect of serum lipids on the risk of breast cancer incidence. PubMed, Web of Science, Scopus, and EMBASE were searched systematically from January 1998 to April 2019. Inclusion criteria were English observational studies (cohort or case-control) and the concentration of at least one of the lipid profile components (total cholesterol/triglycerides/low-density lipoprotein cholesterol/high-density lipoprotein cholesterol) measured before a diagnosis of breast cancer (BC). The studies were included in which the relative risk (RR) had been reported with 95% confidence intervals (CIs). A random-effects model was used. A total of 25 studies were found, including 2,882,789 participants in cohort studies with 45,481 cases with BC, and 1983 BC cases and 2963 case-control studies. Combined RR of cohort studies for the highest versus lowest for the BC was LDL-C: 0.95 (95% CI: 0.89-1.01), triglycerides (TG): 0.95 (95% CI: 0.91-0.99; P = 0.02), total cholesterol (TC): 0.98 (95% CI: 0.91-1.05), and HDL-C: 0.86 (95% CI: 0.63-1.18). Combined RR of case-control studies for the highest versus lowest was LDL-C: 1.08 (95% CI: 0.78-1.48), TG: 1.73 (95% CI: 0.94-3.18), TC: 1.02 (95% CI: 0.80-1.29), and HDL-C: 0.79 (95% CI: 0.65-0.97). Based on the results, it can be concluded that only TG but not TC and/or LDL-C had a significant inverse association with the risk of BC incidence. HDL-C showed a significant protective effect against breast cancer in postmenopausal women and case-control studies.

Association of Hyperlipidemia in Second Trimester of Pregnancy with Maternal and Neonatal Outcomes

Introduction: Pregnancy is a state of metabolic stress associated with high lipid levels; the highest concentration observed during third trimester. The imbalance in the amount of lipidshas been related to maternal-perinatal pathologies such as preeclampsia (PE), gestational diabetes mellitus (GDM) and preterm birth. Aim/Objectives: Our study was aimed at studying the association of serum lipid profile during second trimester with the various adverse pregnancy outcomes. Methods: A cohort of 150 antenatal mothers were recruited and were evaluated for serum lipid profile during the second trimester. They were followed up till delivery and maternal and neonatal outcome, were recorded. Conclusion: It was concluded that there were direct implications of dyslipidemia on maternal and perinatal outcomes. Increase in maternal TG, TC, LDL and VLDL concentrations were the most important changes affecting maternal outcomes and had significant association with GDM, PE and PTB. HDL did not have any association with any adverse maternal or neonatal outcome.

Relationship of Helicobacter Pylori Specific IgG Antibodies with Serum Magenisum and Serum Lipid Profile in Patients on Maintenance Hemodialysis

Background: Helicobacter pylori are thought to play an important role in the pathogenesis of activegastritis and other upper mucosal lesions in chronic hemodialysis patient which thoughtto result in dyspeptic symptoms. Aim:The aim of the study is to determine the prevalence of Helicobacter pylori infection in patient on maintenance hemodialysis and to assess the probable association of serum lipid profile and serum magnesium with H. pylori infection in these patients. Material &Methods: This cross-sectional study was conducted on patients with end stage renal disease who were undergoing maintenance hemodialysis treatment.were enrolled in the present studya total number of 42 hemodialysis patients (24 male and 18 female), of the total number; 10 were diabetic and 32 were non diabetic. Demographic data including age, gender, duration of hemodialysis and clinical data including diabetes mellitus, upper gastrointestinal symptoms and laboratory measurements were obtained from related questionnaires. Venous blood samples were collected for biochemical analysis of the following markers: serum magnesium, total cholesterol, triglyceride; high density lipoprotein-cholesterol, low density lipoprotein-cholesterol and very low density lipoprotein-cholesterol. Result & Conclusion: We conclude that there was no significant correlation between gender, age, duration of hemodialysis, DM, serum triglyceride, VLDL-C and magnesium and H. pylori infection in these patients.

Association of serum lipid profiles and dietary intakes of vitamin E and fiber with psoriasis severity.

Background:Dyslipidemia has been reportedly associated with an increased risk of atherosclerosis among psoriatic patients. Dietary intake can be a key factor in the pathophysiology of psoriasis. Herein, we assessed serum lipid profile and dietary intake in psoriatic patients, in comparison with healthy subjects.Methods:In this case-control study, 45 psoriatic patients and 43 healthy controls were evaluated. We estimated the macro/micronutrient intakes and energy, using a food frequency questionnaire (FFQ). Anthropometric parameters and serum levels of triglyceride (TG), high-density lipoproteins (HDL), low-density lipoproteins (LDL), and very low-density lipoproteins were assessed. The case group was categorized by severity measured by PASI score (mild<10, moderate 10-20, severe >20). Diet plan 6.0 was used to analyze FFQs and data were analyzed in SPSS 16.0, with p<0.05 considered significant.Results:The case group had markedly higher body mass index (BMI), LDL, and cholesterol and significantly lower HDL compared with controls (p<0.05). Carbohydrate, energy, fat intakes were significantly higher in cases, while folate, fiber, and vitamin E intakes were significantly lower in the case group, compared with the control group (p<0.05). BMI, cholesterol, and triglyceride values and dietary intakes of fiber and vitamin E were significantly associated with severity of psoriasis (p<0.05).Conclusion:Serum lipid profile and dietary intake are substantially important in psoriasis severity. Therefore, close monitoring of lipid profile and BMI during admission and follow-up and dietary modification can improve the severity of psoriasis.

Association of Serum Lipid Profile with Severity of Acute Pancreatitis

Association of Serum Lipid Profile with Severity of Acute Pancreatitis

Maternal plasma lipid concentration in third trimester of women with preeclampsia and normotensive pregnancy

Background: Preeclampsia is one of complications of pregnancy. It is responsible for morbidity for mother and fetus. Preeclampsia is a pregnancy multisystem disorder. Abnormal lipid profile has an effect on endothelial dysfunction. The association of serum lipid profile with preeclampsia is suggested to reflect new diagnostic tools. Pregnancy dyslipidemia is associated with an increased risk of preeclampsia. Compared to healthy pregnancy, women with preeclampsia have an abnormal lipid profile. Aim of the work: The aim of this work is comparison between normotensive women and preeclamptic women by serum lipid profile at third trimester. Patients and Methods: The present study conducted on 70 pregnant women in the Department of Obstetrics and Gynecology, at Al-Azhar University hospital [Damietta], which was conducted during 2019 [from April to December]. A study comprised 35 normotensive pregnant women as controls and 35 preeclampsia cases. The blood samples were analyzed for serum triglycerides [TGs], total cholesterol [TC], high-density lipoprotein-cholesterol [HDL-C], low-density Lipoprotein-Cholesterol [LDL-C], very low-density Lipoprotein-Cholesterol [VLDL-C], Apo lipoprotein- A1 [Apo-A1] and Apo lipoprotein- B[Apo-B].Results: There was significant difference between group A and B as regard Apo B/ Apo A1, cholesterol, TGS, LDL and VLDL. They are higher in group B.Conclusion: In the third trimester of pregnancy, preeclamptic women have altered levels of serum lipid profile. The most significant test is Apo B/A1 ratio with accuracy [72.7%].

Serum lipids and risk of atherosclerosis in xanthelasma palpebrarum: A systematic review and meta-analysis

The association between dyslipidemia and xanthelasma palpebrarum (XP) remains controversial, and no definite evidence has indicated atherosclerosis risk in patients with XP. The present study was a systematic review and meta-analysis to elucidate the association of serum lipid profiles and risk of atherosclerotic diseases with XP. We systematically searched for the eligible comparative studies published before April 15, 2019, in the databases of PubMed, Web of Science, Embase, and Cochrane Library. A random-effects model was used to calculate the standard mean difference with 95% confidence interval for each pooled estimate. The qualitative analyses included 15 case-control studies with 854 patients with XP. Compared with the controls, the patients with XP had significantly higher serum levels of total cholesterol and low-density lipoproteins, significantly higher apolipoprotein B levels, and relatively lower apolipoprotein A1 levels, and the carotid intima-media thickness was significantly higher. Patients with XP had significantly higher serum levels of atherogenic low-density lipoproteins and bore significantly higher risk of atherosclerosis than the controls. Careful monitoring and targeted intervention for prevention of cardiovascular diseases is essential for these patients.

A clinical study of serum lipid profile in benign breast disease in a tertiary care hospital

Background: The aim of the study was to evaluate an association of serum lipid profile in women with benign breast disease and to analyze a possible relationship between serum lipid profile and benign breast diseases with emphasis to laboratory findings.Methods: Hospital based study carried out at ACS Medical College, Chennai, during the period of June 2018 to November 2018. 75 women in General Surgery ward/outpatient were included in the study. Subjects included in the study were women of age between 16 to 35 years, provided they fulfilled inclusion and exclusion criteria. History was noted, serum lipid profile was done. Results were noted and analysed.Results: Out of 75 subjects, 21.3% of women with benign breast disease were having elevated serum lipid profile.Conclusions: It is concluded that benign breast disease is associated with altered serum lipid profile namely hyperlipidemia. Therefore, routine screening and treatment of this condition is must among women with benign breast disease by dietary management, use of anti-hyperlipidemic drugs to achieve long lasting cure and to prevent possible future recurrences.

Association of serum lipid profile and insulin resistance in polycystic ovary syndrome (PCOs) women in Ahvaz, Iran

Association of serum lipid profile and insulin resistance in polycystic ovary syndrome (PCOs) women in Ahvaz, Iran

Association of Diabetic Retinopathy and Lipid Profile in Diabetic Patients in Mathura District

Background: It is estimated that diabetes mellitus affects 4 percent of the world’s population, almost half of whom have some degree of diabetic retinopathy at any given time. Elevated serum lipid levels are associated with an increased risk of retinal hard exudate in persons with diabetic retinopathy. Therefore the current study was undertaken to determine the association of serum lipid profile with diabetic retinopathy and its severity. Subjects and Methods: One hundred fifty diabetic patients, out of these, 75 diabetic patients with retinopathy served as the study group I and 75 diabetic patients with no retinopathy formed group II (control group). Simultaneously, 75 age and sex matched healthy subjects were also studied as controls (group III). Serum total cholesterol, serum triglyceride, serum low density lipoprotein and serum high density lipoprotein were measured by using enzymatic method and autoanylyser. Fasting blood sugar and post prandial blood sugar were estimated by using GOD POD method. Results: Most of the patients in Group I had some degree of visual impairment. However there was no statistical significance with p >0.05. The mean value of total cholesterol was higher in both group I and group II with value being higher in group1 (229.09mg/dl) as compared to group II (215.32mg/dl). Triglyceride levels also followed the similar trend with group I having mean value of 238.95mg/dl and group II having 179.93 mg/dl. But only total cholesterol value had statistical significance p < 0.05. Conclusion: The present study demonstrated statistically significant correlation between diabetic retinopathy and hypercholesterolemia. Increased cholesterol level was significantly associated with the occurrence of all grades of retinopathy especially severe NPDR, very severe NPDR and PDR. No correlation was found between lipid profile and visual acuity. These data suggest that hyperlipidaemia should be promptly treated in diabetic patients.

Association of Serum Lipid Profile With Coronary Computed Tomographic Angiography–derived Morphologic and Functional Quantitative Plaque Markers

Recent advances in image quality of coronary computed tomographic angiography (cCTA) have enabled improved characterization of coronary plaques. Thus, we investigated the association between quantitative morphological plaque markers obtained by cCTA and serum lipid levels in patients with suspected or known coronary artery disease. We retrospectively analyzed data of 119 statin-naive patients (55±14 y, 66% men) who underwent clinically indicated cCTA between January 2013 and February 2017. Patients were subdivided into a plaque and a no-plaque group. Quantitative and morphologic plaque markers, such as segment involvement score, segment stenosis score, remodeling index, napkin-ring sign, total plaque volume, calcified plaque volume, and noncalcified plaque volume (NCPV) and plaque composition, were analyzed using a semiautomated plaque software prototype. Total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein, low-density lipoprotein/high-density lipoprotein ratio, and triglycerides were determine in both groups. Higher age (61±11 y vs. 52±14 y, P<0.0001) and a higher likelihood of male gender (77% vs. 56%, P<0.0001) were observed in the plaque group. Differences in lipid levels were neither observed for differentiation between plaque presence or absence, nor after subcategorization for plaque composition. LDL serum levels >160 mg/dL correlated with higher NCPV compared with patients with LDL between 100 and 160 mg/dL (112 vs. 27 mm, P=0.037). Other markers were comparable between the different groups. Statin-naive patients with known or suspected coronary artery disease did not show differences in lipid levels related to plaque composition by cCTA. Patients with plaques tended to be men and were significantly older. High LDL levels correlated with high NCPV.

Serum Lipid Profile in Adult Nephrotic Syndrome Patients

Background: The nephrotic syndrome is a constellation of abnormalities that includes massive proteinuria, hypoalbuminaemia and oedema. Lipid abnormalities have an important biochemical basis in the disease process of adult nephrotic syndrome. Dyslipidaemia in nephrotic syndrome is involved in cardiovascular risk and also accelerates the progression of glomerular dysfunction.Objective: To find out the association between serum lipid profile and nephrotic syndrome in adult.Materials and method: This case control study was carried out in the Department of Biochemistry, Dhaka Medical College, Dhaka, Bangladesh, during the period of July 2013 to June 2014 to evaluate the association of serum lipid profile in adult patients with nephrotic syndrome. One hundred (100) study subjects were included, among them fifty (50) were diagnosed adult nephrotic syndrome patients selected as case and fifty (50) were age and sex matched healthy adult individuals selected as control. Serum lipid profile and serum albumin were measured for both case and control. All the statistical analyses were done by using SPSS for Windows version 20.0.Results: Mean±SD of serum total cholesterol (Tchol), triacylglycerol (TAG), high density lipoprotein (HDL-C), and low density lipoprotein (LDL-C) of case were 288.23±35.67 mg/dL, 174.53±18.86 mg/dL, 23.71±4.58 mg/dL, and 231.16±34.28 mg/dL respectively and that of control were 171.04± 24.36 mg/dL, 129.58± 23.47 mg/dL, 37.5± 7.01 mg/dL, and 103.58±36.83 mg/dL respectively. Serum Tchol, TAG, LDL-C levels were significantly higher in cases than the control (p&lt;0.0001) and serum HDL-C level was significantly lower in cases than the control (p&lt;0.0001).Conclusion: Dyslipidaemia is associated with adult nephrotic syndrome. Routine check-up of lipid profile will help to prevent the development of cardiovascular and cerebrovascular complications in adult nephrotic syndrome patients.Delta Med Col J. Jan 2018 6(2): 78-81

Association of serum lipid profile and cigarette smoking among middle-aged Lithuanian adults

Association of serum lipid profile and cigarette smoking among middle-aged Lithuanian adults

Association of serum lipid profile and diabetes mellitus among middle aged Lithuanian adults

Aim: The aim of the study was to assess the differences of lipidogram parameters between diabetes mellitus (DM) group and non-diabetic group of middle aged Lithuanian adults participating in Lithuanian High Cardiovascular Risk primary prevention programme.

Association of serum lipid profile and family history of coronary heart disease among middle aged Lithuanian adults

Association of serum lipid profile and family history of coronary heart disease among middle aged Lithuanian adults